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| 1 | Clinical significance of loss of heterozygosity for M6P/IGF2R in patients with primary hepatocellular carcinoma显示文摘AIM:To investigate the relationship between loss of heterozygosity (LOH) for mannose 6-phosphate/insulin- like growth factor 2 receptor (M6P/IGF2R) and the outcomes for primary HCC patients treated with partial hepatectomy. METHODS: The LOH for M6P/IGF2R in primary HCC patients was assessed using six different gene-specific nucleotide polymorphisms. The patients studied were enrolled to undergo partial hepatectomy. RESULTS: M6P/IGF2R was found to be polymorphic in 73.3% (22/30) of the patients, and of these patients, 50.0% (11/22) had tumors showing LOH in M6P/IGF2R. Loss of heterozygosity in M6P/IGF2R was associated with significant reductions in the two year overall survival rate (24.9% vs 65.5%; P = 0.04) and the disease-free survival rate (17.8% vs 59.3%; P = 0.03). CONCLUSION: These results show M6P/IGF2R LOH predicts poor clinical outcomes in surgically resected primary HCC patients. | Hong Seok Jang Ki Mun Kang Byung Ock Choi Gyu Young Chai Soon Chan Hong Woo Song Ha Randy L Jirtle | 2008 | World Journal of Gastroenterology2008，14，9： | 12 |
| 2 | 胡萝卜软腐果胶杆菌巴西亚种(Pectobacterium carotovorum subsp.brasiliense)引起的黄瓜细菌性软腐病在中国发生显示文摘2014—2015年,在中国山东、山西、河北、河南、辽宁等省的黄瓜茎叶上发生了毁灭性的细菌性软腐病,造成了黄瓜产业严重的经济损失。黄瓜叶片、茎、叶柄和果实表面出现流胶;茎基部呈深褐色进而出现湿腐。受侵染的黄瓜叶边缘出现黄斑和湿腐症状,并逐渐扩散至叶片中心。从受侵染组织中分离出45个细菌菌株,在形态学特性鉴定、生理学、生物化学和16Sr RNA基因序列分析的基础上,将病原体鉴定为胡萝卜软腐果胶杆菌(Pectobacterium carotovorum)。多位点序列分析(MLSA)证实,分离菌株是胡萝卜软腐果胶杆菌巴西亚种[Pectobacterium carotovorum subsp.brasiliensis(Pcb)],病原菌归入进化枝II。重新分离获得与原始菌株相同的菌株,证实了分离菌株的致病力。寄主范围测试表明,该菌株具有广泛的寄主范围。目前为止,这是对Pcb引起的黄瓜软腐病——这一对黄瓜生产具有重要经济影响的病害在中国乃至全球范围内的首次报道。 | 冯志琴(译) meng x l chai a l shi y x xie x w ma z h li b j | 2017 | 中国植保导刊2017，37，7： | 10 |
| 3 | A theoretical analysis on self-organized formation of microbial biofilms 显示文摘 | Chen L M Chai L H | 2006 | Physica A: Statistical Mechanics and Its Applications2006，370，2： | 1 |
| 4 | 显示文摘 | Wang Y Y Peng W J Chai L Y | 2004 | J Cent Southuniv Technol2004，11，4： | 1 |
| 5 | Research on environmental-friendly anodizing process for magnesium alloys显示文摘 | LUO S L DAI L ZHOU H H CHAI L Y KUANG Y F | 2005 | Journal of Hunan University (Natural Sciences)2005，32，3： | 1 |
| 6 | Fhylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from breeding foxes, raccoon dogs and minks in China 显示文摘 | Zhao J J Yan X J Chai X L | 2010 | Veterinary Microbiology2010，140，： | 1 |
| 7 | Optimization ofmultiplex PCR conditions for rapid detection of Escherichia coli O157:H7 virulence genes 显示文摘 | Jeshveen S S Chai L C Pui C F | 2012 | International Food Reseach Journal2012，19，2： | 1 |
| 8 | The effects of shopping orientations, online trust and prior online pur- chase experience toward customers' online purchase inten- tion显示文摘 | Ling K C Chai L T Piew T H | 2010 | International Business Research2010，3，3： | 1 |
| 9 | Glial cell line-derived neurotrophic factor enchances axonal regeneration following sciatic nerve transection in adult rats显示文摘 | Chen ZY Chai YF Cao L | 2001 | Brain Res2001，902，2： | 1 |
| 10 | A new statistical dynamic analysis on vegetation patterns in land ecosystems显示文摘 | Feng Q Y Chai L H | 2008 | Physica A: Statistical Mechanics and Its Applications2008，387，14： | 1 |
| 11 | An application of relative difference quotient algorithm to topology optimization of truss structures with discrete variables显示文摘 | Chai S Shi L S Sun H C | 1999 | Struc Optim1999，18，： | 1 |
| 12 | Agrobacterium-mediated transformation of Korean lawngrass (Zoysia japonica)显示文摘 | Chai M L Kim D H | 2000 | J Kor Soc Hort Sci2000，41，5： | 1 |
| 13 | The application of bioflocculant for the removal of humic acids from stabilized landfill leachates 显示文摘 | Zouboulis A 1 Chai X L Katsoyiannis I A | 2004 | J Environ Manag2004，70，： | 1 |
| 14 | Lyotropic liquid crystalline phases formed in an ionic liquid显示文摘 | WANG L CHEN X CHAI Y | 2004 | Chem Commun2004，，： | 1 |
| 15 | Enhanced epoxy/silica composites mechanical properties by introducing graphene oxide to the interface显示文摘 | Chen L Chai S Liu K | 2012 | ACS applied materials & interfaces2012，4，8： | 1 |
| 16 | 查看详情显示文摘 | Chow J D Chai W L | | 0，，： | 1 |
| 17 | Preparation and application of polymer dust suppressants in coal transportation under microwave irradiation 显示文摘 | Li L S Chai Q Wang B | 2012 | Advanced Materials Research2012，1536，396： | 1 |
| 18 | Effect of combined acupuncture and Chinese herbal fomlula on the motor function and activities of daily living in post-stroke patients 显示文摘 | Wu YC Chai L | 2011 | J Acupunct Thina Sci2011，9，5： | 1 |
| 19 | Estimation of genetic parameters for growth traits in cultured clam Meretrix meretrix (Bivalvia: Veneridae) using the Bayesian method based on Gibbs sampling显示文摘 | Wang H X Chai X L Liu B Z | 2011 | Aquaculture Re- search2011，42，2： | 1 |
| 20 | MPC a cascade MPC control structurefor a PMSM with speed ripple minimization 显示文摘 | CHAI S WANG L ROGERS | 2013 | IEEE Transactionson Industrial Electronics2013，60，29： | 1 |
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