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| 1 | New Insights into Plant Isoprenoid Metabolism显示文摘Isoprenoids are a hugely diverse family of compounds derived from the C5 precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).Although all free-living organisms synthesize isoprenoids,they are particularly abundant and diverse in plants,with tens of thousands structures known to date.The highest variety of plant isoprenoids are specialized (secondary) metabolites that participate in the interaction of plants with their environment.These include pigments,volatiles,and defense compounds,some of which have applications in industry and agriculture.For example,isoprenoid drugs are used against cancer (taxol) or malaria (artemisin).But plants also synthesize isoprenoids with essential (primary) functions in respiration (ubiquinone),photosynthesis (carotenoids,chlorophylls,tocopherols,phylIoquinones,plastoquinone),membrane architecture (sterols),and growth regulation (brassinosteroids,cytokinins,gibberellins,abscisic acid,strigolactones).Despite their economic importance and biological relevance,our knowledge of the core pathways for the production of the universal isoprenoid precursors IPP and DMAPP in plant cells remained incomplete until the mid-1990s.Impressive progress in the last decade has resulted in the complete elucidation of several isoprenoid pathways,the identification of regulatory mechanisms,the discovery of new functions and properties of specific isoprenoids,and the successful manipulation of isoprenoid biosynthesis in a number of metabolic engineering approaches.In this update article,we will discuss some of the most recent advances in the plant isoprenoid field,focusing on the pathways supplying the C5 precursors in plant cells and the novel insights into regulatory matters. | Pablo Pulido Catalina Perello Manuel Rodriguez-Concepcion | 2012 | Molecular Plant2012，5，5： | 22 |
| 2 | Anti-oxidation actions of curcumin in two forms of bed rest:oxidative stress serum and salivary markers显示文摘Objective:To determine the preventive effects of curcumin on peroxidative damage under two bed rest conditions.Methods:20 healthy male(10 with curcumin and 10 without curcumin ) volunteers were selected.They were studied before,during,and just on bed rest conditions at -6°head-down-tilt(HDT) bed rest and bed rest position(BD) for 10 days.We measured the salivary and serum oxidative markers such as Malonaldehyde,8-hydroxydeoxyguanosine, vitamin C and E just before HDT & BD.during HDT & BD experiment,and in course time of recovery with curcumin and without curcumin groups.Results:The values of serum and salivary vitamin C & E showed statistically significant decrease in both bed rest conditions as compared to those of the conditions before and during the recovery stage.However,these levels were not significantly lowered in curcumin groups in contrast to the groups without curcumin (P>0.05).MDA and 8-OHdG levels showed significant increase in simulating microgravity and zero gravity conditions as compared to those before and in the recovery stage.However,these levels were lower in curcumin groups in contrast to the groups without curcumin(P<0.05).Serum and salivary correlation analysis revealed a strong and highly significant correlation for MDA. vitamin C & E and 8 dihydro-2 deoxyguanosine(8-OHdG) in the conditions before,during and in the recovery periods in both bed rest conditions.Since saliva collection is easy and noninvasive, measurements of salivary marker levels may prove to be useful in the space research. Conclusions:Curcumin prevents peroxidative damage in both bed rest conditions.Further study is required on antioxidation actions of curcumin in space microgravity conditions. | Balwant Rai Jasdeep Kaur Maria Catalina | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，8： | 9 |
| 3 | Serum 25-hydroxyvitamin D concentration and inflammatory bowel disease characteristics in Romania显示文摘AIM:To describe the relationship between vitamin D levels and inflammatory bowel disease(IBD)characteristics in northeastern Romanian patients.METHODS:This was a prospective study of 47 consecutive IBD patients admitted to The Institute of Gastroenterology and Hepatology in Iasi,Romania between March 2011 and June 2012.The diagnosis of IBD was established based on endoscopic,histologic and radiologic findings.Demographic data,disease characteristics,ongoing treatments and biological parameters of patients(including markers of inflammation:C-reactive protein level,fibrinogen level,and erythrocyte sedimentation rate)were recorded.Serum vitamin D levels were measured and compared with age-and sexmatched healthy volunteers from the same geographic area.Vitamin D levels were defined as sufficient(>30ng/mL),insufficient(20-30 ng/mL),or severely defi-cient(<20 ng/mL).RESULTS:Thirty-three of the IBD patients included in this study had ulcerative colitis(UC)and 14 had Crohn’s disease(CD).Only 24%of the UC patients and 21%of the CD patients had sufficient vitamin D levels.The vitamin D levels were significantly lower in the CD patients with moderate to severe disease activity compared to the CD patients in remission or with mild disease activity(16±6 ng/mL vs 26±7 ng/mL;16±6 ng/mL vs 31±9 ng/mL,respectively,P<0.05).Vitamin D levels in the UC patients were not influenced by disease activity and no correlation was observed with the inflammation markers tested(C-reactive protein,fibrinogen,and erythrocyte sedimentation rate).No association was observed between vitamin D levels and smoking status or ongoing medication(5ASA,steroids,and anti-TNFα).Newly diagnosed IBD patients had lower vitamin D levels than patients with established cases,though these differences were not significant(UC:22±9 ng/mL vs 26±12 ng/mL;CD:18±6 ng/mL vs 27±11 ng/mL,respectively).Although no association was found between the season during which the visit was scheduled and vitamin D levels,the UC patients assessed during the winter tended to have lower levels than those assessed during the summer(22±9 ng/mL vs 28±13 ng/mL,respectively).CONCLUSION:Vitamin D levels are significantly reduced in IBD patients in northeastern Romania,with the lowest levels occurring in CD patients with moderate to severe disease activity. | Gabriela Dumitrescu Catalina Mihai Mihaela Dranga Cristina Cijevschi Prelipcean | 2014 | World Journal of Gastroenterology2014，20，9： | 8 |
| 4 | Feeder-free maintenance of hESCs in mesenchymal stem cell-conditioned media: distinct requirements for TGF-β and IGF-Ⅱ显示文摘 | Rosa Montes Gertrudis Ligero Laura Sanchez Purificacidn Catalina Teresa de la Cueva Ana Nieto Gustavo J Melen Ruth Rubio Javier Garcia-Castro Clara Bueno Pablo Menendez | 2009 | Cell Research2009，19，6： | 7 |
| 5 | Portal hypertensive colopathy is associated with portal hypertension severity in cirrhotic patients显示文摘AIM:To assess the prevalence of portal hypertension (PH) related colorectal lesions in liver transplant candidates, and to evaluate its association with the severity of PH.METHODS: Between October 2004 and December 2005, colonoscopy was performed in 92 cirrhotic liver transplant candidates. We described the lesions resulting from colorectal PH and their association with the grade of PH in 77 patients who underwent measurement of hepatic venous pressure gradient (HVPG).RESULTS: Mean age was 55 years and 80.7% of patients were men. The main etiology of cirrhosis was alcoholism (45.5%). Portal hypertensive colopathy (PHC) was found in 23.9%, colonic varices in 7.6% and polyps in 38% of patients (adenomatous type 65.2%). One asymptomatic patient had a well-differentiated adenocarcinoma. The manifestations of colorectal PH were not associated with the etiology of liver disease or with the Child-Pugh grade. Ninety percent of patients with colopathy presented with gastroesopha-geal varices (GEV), and 27.5% of patients with GEV presented with colopathy (P=0.12). A relationship between higher values of HVPG and presence of col-opathy was observed (19.9±6.2 mmHg vs 16.8±5.4 mmHg, P=0.045), but not with the grade of col-opathy (P=0.13). Preneoplastic polyps and neoplasm (P=0.02) and spontaneous bacterial peritonitis (P=0.006) were more prevalent in patients with colopathy. We did not observe any association between previous β-blocker therapy and the presence of colorectal portal hypertensive vasculopathy.CONCLUSION: PHC is common in cirrhotic liver trans-plant candidates and is associated with higher portal pressure. | Antonio Diaz-Sanchez Oscar Nuez-Martinez Cecilia Gonzalez-Asanza Ana Matilla Beatriz Merino Diego Rincon Inmaculada Beceiro Maria Vega Catalina Magdalena Salcedo Rafael Baares Gerardo Clemente | 2009 | World Journal of Gastroenterology2009，15，38： | 6 |
| 6 | Chest neoplasms with infectious etiologies显示文摘A wide spectrum of thoracic tumors have known or suspected viral etiologies.Oncogenic viruses can be classified by the type of genomic material they contain.Neoplastic conditions found to have viral etiologies include post-transplant lymphoproliferative disease,lymphoid granulomatosis,Kaposi's sarcoma,Castleman's disease, recurrent respiratory papillomatosis,lung cancer,malignant mesothelioma,leukemia and lymphomas.Viruses involved in these conditions include Epstein-Barr virus, human herpes virus 8,human papillomavirus,Simian virus 40,human immunodeficiency virus,and Human T-lymphotropic virus.Imaging findings,epidemiology and mechanism of transmission for these diseases are reviewed in detail to gain a more thorough appreciation of disease pathophysiology for the chest radiologist. | Carlos S Restrepo Melissa M Chen Santiago Martinez-Jimenez Jorge Carrillo Catalina Restrepo | 2011 | World Journal of Radiology2011，3，12： | 6 |
| 7 | Distributed Algorithms for Event Reporting in Mobile-Sink WSNs for Internet of Things显示文摘Wireless Sensor Networks(WSNs) have many applications, such as climate monitoring systems, fire detection, smart homes, and smart cities. It is expected that WSNs will be integrated into the Internet of Things(IoT)and participate in various tasks. WSNs play an important role monitoring and reporting environment information and collecting surrounding context. In this paper we consider a WSN deployed for an application such as environment monitoring, and a mobile sink which acts as the gateway between the Internet and the WSN. Data gathering is a challenging problem in WSNs and in the IoT because the information has to be available quickly and effectively without delays and redundancies. In this paper we propose several distributed algorithms for composite event detection and reporting to a mobile sink. Once data is collected by the sink, it can be shared using the IoT infrastructure. We analyze the performance of our algorithms using WSNet simulator, which is specially designed for event-based WSNs. We measure various metrics such as average residual energy, percentage of composite events processed successfully at the sink, and the average number of hops to reach the sink. | Catalina Aranzazu-Suescun Mihaela Cardei | 2017 | Tsinghua Science and Technology2017，22，4： | 5 |
| 8 | Antithrombotic treatment tailoring and risk score evaluation in elderly patients diagnosed with an acute coronary syndrome显示文摘 | Alexandru Nicolae Mischie Catalina Liliana Andrei Crina Sinescu Gani Bajraktari Eugen Ivan Georgios Nikolaos Chatziathanasiou Michele Schiariti | 2017 | Journal of Geriatric Cardiology2017，14，7： | 5 |
| 9 | New Clues that May Link Osteoporosis to the Circulating Lipid Profile显示文摘Bone Mineral Density(BMD)is a gold standard for the diagnosis of osteoporosis and is also important in the assessment of fracture risk.Other risk factors have been identified that together make up fracture risk assessment tools such as FRAX.Another potential factor,circulating lipids,has been suggested because of reports linking statins to fracture risk reduction.We analyzed the lipid profile in a cohort of women diagnosed with postmenopausal osteoporosis based on bone density determination:610 women with osteoporosis(mean lumbar spine T-score-3.16±0.81,mean yrs.since menopause 15.79±8.9)were grouped according to age at evaluation(<50 years,51-60 years,61-70 years,>70 years),the presence/absence of a history of a fragility fracture,statin and/or antiresorptive drug use.There was no correlation between BMD and Body Mass Index(BMI:P>0.05,r2<0.02).However,when BMD was correlated with both BMI and the lipid profile(Triglycerides,Cholesterol,LDLc,HDLc),significant correlations were found in 5 cohorts:51-60 years with fractures(n=61,r2=0.14,P<0.01),61-70 years(n=201,r2=0.09,P<0.01)with fractures(n=88,r2=0.14,P<0.01)or without fractures(n=113,r2=0.24,P=0.02)and over 70 years(n=247,r2=0.11,P<0.01). | Catalina Poiana Valentin Radoi Mara Carsote John P. Bilezikian | 2013 | Bone Research2013，1，3： | 5 |
| 10 | Red pigment production by Penicillium purpurogenum GH2 is influenced by pH and temperature显示文摘The combined effects of pH and temperature on red pigment production and fungal morphology were evaluated in a submerged culture of Penicillium purpurogenum GH2, using Czapek-Dox media with D-xylose as a carbon source. An experimental design with a factorial fix was used: three pH values (5, 7, and 9) and two temperature levels (24 and 34 °C) were evaluated. The highest production of red pigment (2.46 g/L) was reached with a pH value of 5 and a temperature of 24 °C. Biomass and red pigment production were not directly associated. This study demon- strates that P. purpurogenum GH2 produces a pigment of potential interest to the food industry. It also shows the feasibility of producing and obtaining natural water-soluble pigments for potential use in food industries. A strong combined effect (p<0.05) of pH and temperature was associated with maximal red pigment production (2.46 g/L). | Alejandro MéNDEZ Catalina PéREZ Julio Cesar MONTAéZ Gabriela MARTíNEZ Cristóbal Noé AGUILAR | 2011 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2011，12，12： | 4 |
| 11 | Holistic Disaster Risk Evaluation for the Urban Risk Management Plan of Manizales,Colombia显示文摘Disaster risk depends on both the physical vulnerability and a wide range of social, economic, and environmental aspects of a society. For a better risk understanding, a holistic or integrated perspective was considered when risk was assessed for the city of Manizales, Colombia. This assessment accounts not only for the expected physical damage and loss, but also for the socioeconomic vulnerability factors that favor secondorder effects in a disaster. This comprehensive approach allows the identification of different aspects related to physical vulnerability, social fragility, and lack of resilience that can be improved, thus enhancing integrated disaster risk management actions. The outcomes of this comprehensive assessment are currently being used as input to update the disaster risk management plan of Manizales. | Martha Liliana Carreno Omar-Darío Cardona Alex H.Barbat Dora Catalina Suarez María del Pilar Perez Lizardo Narvaez | 2017 | International Journal of Disaster Risk Science2017，8，3： | 4 |
| 12 | Self-assemblies of plasmonic gold/layered double hydroxides with highly efficient antiviral effect against the hepatitis B virus显示文摘工程建筑群 nanocomposites 明确地指向肝炎 B 病毒(HBV ) 并且克服象有限功效和严肃的副作用那样的治疗很正在质问的电流的限制。第一次,这里,设计 plasmonic 黄金和分层的双氢氧化物 self-assemblies (AuNPs/LDHs ) 的抗病毒的效果被表明,用象为传染 virions 和 subviral 粒子的病毒的复制,汇编,和分泌物的一个模型病毒和导出 hepatoma 的 HepG2.2.215 房间的 HBV。 AuNPs/LDHs 被在小 AuNPs 的一个简单、划算的过程获得(~ 3.5 nm )直接在更大的 LDH nanoparticles 的表面上被获得并且组织(~ 150 nm )由利用 MgLDH 的能力, ZnLDH ,并且在 Au 的水的解决方案表明他们的结构的存储器的 MgFeLDH ( O 2 CCH 3)3。自己组装 AuNPs 和 LDH 的途径被传播估计电子显微镜学(TEM ) , X 光检查光电子光谱学(XPS ) ,粉末 X 光检查衍射(PXRD ) ,和 UVVis 分析(UVVis ) 。测试的所有 AuNPs/LDHs 减少了数量病毒并且多达 80% 免除对待的房间并且展出了好 cytocompatibility 的 subviral 粒子。AuNPs/MgFeLDH 为整个集中范围与 HBV 分泌物的超过 90% 抑制显示出最高抗病毒的 HBV 反应。HBV 抑制的机制上的初步的研究表明面对 AuNPs/LDHs, HBV 粒子在对待的房间以内被扣押。这些 Au/LDH nanocomposites 的抗病毒、低的细胞毒素的 plasmonic 性质显示他们保持重要潜力为肝炎 B 的处理作为新奇有效治疗学被定制。 | Gabriela Carja Elena Florentina Grosu Catalina Petrarean Norica Nichita | 2015 | Nano Research2015，8，11： | 4 |
| 13 | Immunotherapy and immunoescape in colorectal cancer显示文摘Immunotherapy encompasses a variety of interventions and techniques with the common goal of eliciting tumor cell destructive immune responses. Colorectal carcinoma often presents as metastatic disease that impedes curative surgery. Novel strategies such as active immunization with dendritic cells (DCs), gene transfer of cytokines into tumor cells or administration of immunostimulatory monoclonal antibodies (such as anti-CD137 or anti-CTLA-4) have been assessed in preclinical studies and are at an early clinical development stage. Importantly, there is accumulating evidence that chemotherapy and immunotherapy can be combined in the treatment of some cases with colorectal cancer, with synergistic potentiation as a result of antigens cross-presented by dendritic cells and/or elimination of competitor or suppressive T lymphocyte populations (regulatory T-cells). However, genetic and epigenetic unstable carcinoma cells frequently evolve mechanisms of immunoevasion that are the result of either loss of antigen presentation, or an active expression of immunosuppressive substances. Some of these actively immunosuppressive mechanisms are inducible by cytokines that signify the arrival of an effector immune response. For example, induction of 2, 3 indoleamine dioxygenase (IDO) by IFNγ in colorectal carcinoma cells. Combinational and balanced strategies fostering antigen presentation, T-cell costimulation and interference with immune regulatory mechanisms will probably take the stage in translational research in the treatment of colorectal carcinoma. | Guillermo Mazzolini Oihana Murillo Catalina Atorrasagasti Juan Dubrot Iigo Tirapu Miguel Rizzo Ainhoa Arina Carlos Alfaro Arantza Azpilicueta Carmen Berasain José L Perez-Gracia Alvaro Gonzalez Ignacio Melero | 2007 | World Journal of Gastroenterology2007，13，44： | 4 |
| 14 | Zn-Mg and Zn-Cu alloys for stenting applications:From nanoscale mechanical characterization to in vitro degradation and biocompatibility显示文摘In the recent decades,zinc(Zn)and its alloys have been drawing attention as promising candidates for bioresorbable cardiovascular stents due to its degradation rate more suitable than magnesium(Mg)and iron(Fe)alloys.However,its mechanical properties need to be improved in order to meet the criteria for vascular stents.This work investigates the mechanical properties,biodegradability and biocompatibility of Zn-Mg and Zn-Cu alloys in order to determine a proper alloy composition for optimal stent performance.Nanoindentation measurements are performed to characterize the mechanical properties at the nanoscale as a function of the Zn microstructure variations induced by alloying.The biodegradation mechanisms are discussed and correlated to microstructure,mechanical performance and bacterial/cell response.Addition of Mg or Cu alloying elements refined the microstructure of Zn and enhanced yield strength(YS)and ultimate tensile strength(UTS)proportional to the volume fraction of secondary phases.Zn-1Mg showed the higher YS and UTS and better performance in terms of degradation stability in Hanks’solution.Zn-Cu alloys presented an antibacterial effect for S.aureus controlled by diffusion mechanisms and by contact.Biocompatibility was dependent on the degradation rate and the nature of the corrosion products. | Claudia García-Mintegui Laura Catalina Córdoba Judit Buxadera-Palomero Andrea Marquina Emilio Jiménez-Piqué Maria-Pau Ginebra JoséLuis Cortina Marta Pegueroles | 2021 | Bioactive Materials2021，6，12： | 4 |
| 15 | Efficacy and Safety of Anticoagulation on Patients With Cirrhosis and Portal Vein Thrombosis显示文摘 | María Gabriela Delgado Susana Seijo Ismael Yepes Linette Achécar Maria Vega Catalina ángeles García–Criado Juan G. Abraldes Joaquín de la Pe?a Rafael Ba?ares Agustín Albillos Jaume Bosch Juan Carlos García–Pagán | 2012 | Clinical Gastroenterology and Hepatology2012，，7： | 3 |
| 16 | Development of an analytical method based on solid-phase extraction and LC-MS/MS for the monitoring of current-use pesticides and their metabolites in human urine显示文摘Pyrethroids,organophosphorus pesticides and fipronil have been listed as priority chemicals in human biomonitoring studies because of their wide use and potential health effects in humans.The determination of 13 pesticides,including pyrethroids(deltamethrin,cypermethrin,permethrin,cyfluthrin,bifenthrin),organophosphorus(chlorpyrifos,chlorpyrifosmethyl,and malathion),fipronil,neonicotinoids(imidacloprid,acetamiprid and thiacloprid)and triazole(prothioconazole),together with 13 corresponding metabolites in human urine samples was achieved by solid-phase extraction and analysis by liquid chromatography coupled to tandem mass spectrometry.All targeted compounds,except malathion dicarboxylic acid,were measured with a mean within-accuracy(n=5)of 71%–114%(RSD:1%–14%)and between-run(n=15)accuracy of 80%–118%(RSD:2%–14%).Limits of quantitation of the targeted analytes ranged from 0.1 to 16 pg/m L.The detection result of urine samples from 25 volunteers indicated that the detection frequencies of 3,5,6-trichloro-2-pyridinol(median:448 pg/m L),6-chloropyridine-3-carboxylic acid(median:193 pg/m L),2-methyl-3-phenylbenzoic acid(median:181 pg/m L),3-phenoxybenzoic acid(median:99 pg/m L),2-isopropyl-6-methyl-4-pyrimidinol(median:77 pg/m L),cyfluthrin(median:59 pg/m L),cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid(cis-DCCA,median:53 pg/m L),trans-DCCA(median:25 pg/m L),prothioconazole(median:21 pg/m L),imidacloprid(median:7 pg/m L),and prothioconazole-desthio(median:1 pg/m L)were>50%.The obtained results show that the validated method is suitable for the human biomonitoring of these currentuse pesticides and their metabolites. | Beibei Gao Giulia Poma Govindan Malarvannan Catalina Dumitrascu Michiel Bastiaensen Minghua Wang Adrian Covaci | 2022 | Journal of Environmental Sciences2022，34，1： | 3 |
| 17 | Antioxidant and antimicrobial activities of rosemary extracts linked to their polyphenol composition显示文摘 | Silvia Moreno Tamara Scheyer Catalina S. Romano Adrián A. Vojnov | 2006 | Free Radical Research2006，，2： | 3 |
| 18 | Management of Helicobacter pylori infection in Latin America: A Delphi technique-based consensus显示文摘AIM: To optimize diagnosis and treatment guidelines for this geographic region, a panel of gastroenterologists, epidemiologists, and basic scientists carried out a structured evaluation of available literature.METHODS: Relevant questions were distributed among the experts, who generated draft statements for consideration by the entire panel. A modified three-round Delphi technique method was used to reach consensus. Critical input was also obtained from representatives of the concerned medical community. The quality of the evidence and level of recommendation supporting each statement was graded according to United States Preventive Services Task Force criteria.RESULTS: A group of ten experts was established. The survey included 15 open-ended questions that were distributed among the experts, who assessed the articles associated with each question. The levels of agreement achieved by the panel were 50% in the first round, 73.3% in the second round and 100% in the third round. Main consensus recommendations included:(1) when available, urea breath and stool antigen test(HpSA) should be used for non-invasive diagnosis;(2) detect and eradicate Helicobacter pylori(H. pylori) in all gastroscopy patients to decrease risk of peptic ulcer disease, prevent o retard progression in patients with preneoplastic lesions, and to prevent recurrence in patients treated for gastric cancer;(3) further investigate implementation issues and health outcomes of H. pylorieradication for primary prevention of gastric cancer in high-risk populations;(4) prescribe standard 14-d triple therapy or sequential therapy for first-line treatment;(5) routinely assess eradication success post-treatment in clinical settings; and(6) select second- and third-line therapies according to antibiotic susceptibility testing.CONCLUSION: These achievable steps toward better region-specific management can be expected to improve clinical health outcomes. | Antonio Rollan Juan Pablo Arab M Constanza Camargo Roberto Candia Paul Harris Catterina Ferreccio Charles S Rabkin Juan Cristóbal Gana Pablo Cortés Rolando Herrero Luisa Durán Apolinaria García Claudio Toledo Alberto Espino Nicole Lustig Alberto Sarfatis Catalina Figueroa Javier Torres Arnoldo Riquelme | 2014 | World Journal of Gastroenterology2014，20，31： | 2 |
| 19 | Oral probiotic VSL #3 attenuates the circulatory disturbances of patients with cirrhosis and ascites显示文摘 | Diego Rincón Javier Vaquero Ana Hernando Evelyn Galindo Cristina Ripoll Marta Puerto Magdalena Salcedo Rubén Francés Ana Matilla María V. Catalina Gerardo Clemente José Such Rafael Ba?ares | 2014 | Liver Int2014，，10： | 2 |
| 20 | The genus Thelonectria(Nectriaceae,Hypocreales,Ascomycota)and closely related species with cylindrocarpon-like asexual states显示文摘The genus Thelonectria and closely related species with cylindrocarpon-like asexual states are a group of perithecial ascomycetes in the family Nectriaceae that occur as saprobes and in few cases as pathogens of hardwood trees,shrubs or other plants.Although a key component of forest ecosystems around the world,species relationships and distributions of these fungi are largely unknown.The objectives of this study were to:1)infer species rank phylogenetic relationships of the genus Thelonectria and closely related species with cylindrocarpon-like asexual states and test the monophyly of each of the groups studied;2)delimit taxa establishing taxon circumscriptions;3)resolve nomenclatural issues by identifying redundantly used names and synonyms;and 4)provide an updated outline to the genus,geographical distributions data and identification tools,specifically diagnostic keys and molecular data that can be used as molecular barcodes.The recovered consensus phylogeny resulted in a narrow circumscription of the genus Thelonectria,based on the type T.discophora,excluding one of the common species T.jungneri.According to the phylogenetic analyses,T.jungneri belongs in a segregate clade that should be recognized as a different genus.In the genus Thelonectria,a total of four new species and three new combinations are recognized.Additionally,three new genera,closely related to Thelonectria,are described to accommodate species displaying a morphological resemblance to those of Thelonectria:Cinnamomeonectria gen.nov.with C.cinnamomea as type species,Macronectria gen.nov.with M.jungneri as type species and including four additional newly described species,and Tumenectria gen.nov.with T.laetidisca as type species. | Catalina Salgado-Salazar Amy YRossman Priscila Chaverri | 2016 | Fungal Diversity2016，，5： | 2 |
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