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| 1 | The emerging role of probiotics in neurodegenerative diseases:new hope for Parkinson’s disease?显示文摘Neurodegenerative disease etiology is still unclear,but different contributing factors,such as lifestyle and genetic factors are involved.Altered components of the gut could play a key role in the gut-brain axis,which is a bidirectional system between the central nervous system and the enteric nervous system.Variations in the composition of the gut microbiota and its function between healthy people and patients have been reported for a variety of human disorders comprising metabolic,autoimmune,cancer,and,notably,neurodegenerative disorders.Diet can alter the microbiota composition,affecting the gutbrain axis function.Different nutraceutical interventions have been devoted to normalizing gut microbiome dysbiosis and to improving biological outcomes in neurological conditions,including the use of probiotics.Preclinical and clinical investigations discussed in this review strengthen the correlation between intestinal microbiota and brain and the concept that modifying the microbiome composition may improve brain neurochemistry,modulating different pathways.This review will discuss the potential use of probiotics for Parkinson’s disease prevention or treatment or as adjuvant therapy,confirming that gut microbiota modulation influences different pro-survival pathways.Future investigations in Parkinson’s disease should consider the role of the gut-brain axis and additional comprehension of the underlying mechanisms is extremely necessary. | Vanessa Castelli Michele d’Angelo Massimiliano Quintiliani Elisabetta Benedetti Maria Grazia Cifone Annamaria Cimini | 2021 | Neural Regeneration Research2021，16，4： | 2 |
| 2 | HOPS: a novel cAMP - dependent shuttling protein involved in protein synthesis regulation显示文摘 | Della Fazia MA Castelli M Bartoli D | 2005 | J Cell Sci2005，118，14： | 1 |
| 3 | Human safety review of ' nano' titanium dioxide and zinc oxide 显示文摘 | SCHILLING K BRADFORD B CASTELLI D | 2010 | Photochem Photobiol gel2010，9，4： | 1 |
| 4 | Prognostic implication of echo- cardiophically determined left Ventricular mass in the Framinham heart study显示文摘 | Levy D Anderson KM Castelli Wp | 1990 | N Engi J Med1990，332，： | 1 |
| 5 | Aerobic fitness and neurocognitive function in healthy preadolescent children 显示文摘 | Hillman C H Castelli D M Buck S M | 2005 | Med Sci Sports Exerc2005，37，11： | 1 |
| 6 | HOPS: a novel cAMP-dependent shuttling protein involved in protein synthesis regulation显示文摘 | Delia Fazia MA Castelli M Bartoli D | 2005 | J Cell Sci2005，118，14： | 1 |
| 7 | Mechanisms of antibacterial action of three monoterpenes显示文摘 | Trombetta D Castelli F Sarpietro M G | 2005 | Antimicrob Agents Chemother2005，49，6： | 1 |
| 8 | Land data assimilation with satellite measurements for the estimation of surface energy balance components and surface control on evaporation显示文摘 | BONI G ENTEKHABI D CASTELLI F | 2001 | Water Resources Research2001，37，6： | 1 |
| 9 | Paramagnetic Lanthanide(Ⅲ) complexes as pH-sensitive chemical ex- change saturation transfer (CEST) contrast agents for MRI applications显示文摘 | Aime S Barge A Delli Castelli D etal | 2002 | Magn Reson Med2002，47，： | 1 |
| 10 | Estimation of surface turbulent fluxes through assimilation of radiometric surface temperature sequences显示文摘 | CAPARRINI F CASTELLI F ENTEKHABI D | 2004 | Journal of Hydrometeorology2004，5，1： | 1 |
| 11 | Mechanisms of antibacterial action of three monoterpenes显示文摘 | TROMBETTA D CASTELLI F SARPIETRO M G | 2005 | Antimicrob Agents And Chemother2005，49，6： | 1 |
| 12 | Cholesterol and mortality:thirty years of follow up from the Framingham study显示文摘 | Anderson KM Castelli WP Levy D | 1997 | J AM Med Assoc1997，257，： | 1 |
| 13 | Multifocal branch duct intraductal papillary mucinous neoplasms (IPMNs) of the pancre- as: magnetic resonance (MR) imaging pattern and evolution over time显示文摘 | Castelli F Bosetti D Negrelli R | 2013 | Radiol Med2013，118，6： | 1 |
| 14 | The relation of aero- bic fitness to stroop task performance in preadolescent chil- dren 显示文摘 | Buck S M Hillman C H Castelli D M | 2008 | Medicine & Science in Sports & Exercise2008，40，1： | 1 |
| 15 | A paramagnetic MRI-CEST agent responsive to lactate concentration 显示文摘 | Aime S Delli Castelli D Fedeli F | 2002 | J Am Chem Soc2002，124，： | 1 |
| 16 | Setting the Foundations of Digital Libraries: The DELOS Manifesto显示文摘 | Candela L Castelli D Pagano P | 2007 | D-Lib Magazine2007，13，34： | 1 |
| 17 | Cholesterol and mortality: 30 years of follow-up from the Framingham study显示文摘 | Anderson KM Castelli WP Levy D | 1987 | JAMA1987，257，16： | 1 |
| 18 | Pretreatment of skin with a Ginkgo biloba extract/ sodium carboxymethyl-beta-1,3-glucan formulation appears to inhibit the elicitation of allergic contact dermatitis in man显示文摘 | Castelli D Colin L Camel E | 1998 | Contact Dermatitis1998，38，3： | 1 |
| 19 | Metamrophic veins with kyanite and quartz in the Zhu-Jia-Chong, Dabie Shan, China显示文摘 | Castelli D Rolfo F Compagnoni R | 1998 | The Island Arc1998，7，： | 1 |
| 20 | Variational estimation of soil and vegetation turbulent transfer and heat flux parameters from sequences of multisensor imagery显示文摘 | CAPARRINI F CASTELLI F ENTEKHAB D | 2004 | Water Resources Research2004，40，12： | 1 |
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