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| 1 | Leukemia:研究鉴定出与34种AML白血病亚群相关联的基因突变显示文摘针对成年急性髓细胞白血病(acute myeloid leukemia,AML)患者的一项新的大型研究将80种癌症相关基因突变与5种AML亚型相关联。这5种AML亚型可通过特异性的染色体异常加以确定。在未来,这些发现可能有助指导基因突变测试和治疗决策。 | A-K Eisfeld K Mrózek J Kohlschmidt D Nicolet S Orwick C J Walker K W Kroll J S Blachly A J Carroll J E Kolitz B L Powell E S Wang R M Stone A de la Chapelle J C Byrd C D Bloomfield | 2017 | 现代生物医学进展2017，17，15： | 7 |
| 2 | Enteric bacterial proteases in inflammatory bowel diseasepathophysiology and clinical implications显示文摘Numerous reports have identified a dysbiosis in the intestinal microbiota in patients suffering from inflammatory bowel diseases(IBD),yet the mechanism(s)in which this complex microbial community initiates or perpetuates inflammation remains unclear.The purpose of this review is to present evidence for one such mechanism that implicates enteric microbial derived proteases in the pathogenesis of IBD.We highlight and discuss studies demonstrating that proteases and protease receptors are abundant in the digestive system.Additionally,we investigate studies demonstrating an association between increased luminal protease activity and activation of protease receptors,ultimately resulting in increased intestinal permeability and exacerbation of colitis in animal models as well as in human IBD.Proteases are essential for the normal functioning of bacteria and in some cases can serve as virulence factors for pathogenic bacteria.Although not classified as traditional virulence factors,proteases originating from commensal enteric bacteria also have a potential association with intestinal inflammation via increased enteric permeability.Reports of increased protease activity in stools from IBD patients support a possible mechanism for a dysbiotic enteric microbiota in IBD.A better understanding of these pathways and characterization of the enteric bacteria involved,their proteases,and protease receptors may pave the way for new therapeutic approaches for these diseases. | Ian M Carroll Nitsan Maharshak | 2013 | World Journal of Gastroenterology2013，19，43： | 6 |
| 3 | Synchronization in chaotic systems 显示文摘 | Pecora L M Carroll T L | 1990 | Phys Rev Lett1990，64，： | 2 |
| 4 | Driving systems with chaotic signals显示文摘 | Pecora L M Carroll T L | 1991 | Physics Review A1991，44，4： | 2 |
| 5 | Photochemical production and loss rates of ozone at Sable Island,Nova Sco tis during the North Atlantic Regional Experiment (NARE) 1993 summer intensive 显示文摘 | Duderstadt K Carroll M Sillman S | 1998 | J Geophy Res1998，103，13： | 2 |
| 6 | Synchronization in chaos system显示文摘 | PECORA L M CARROLL T L | 1990 | Phys Rev Lett1990，64，8： | 2 |
| 7 | HiPak^(TM)高压SPTIGBT模块的SOA新基准显示文摘介绍了电压额定值从2.5kV到6.5kV的新型高压HiPakTM IGBT模块系列。新系列HiPakTM模块采用了ABB最新研制的高压SPT IGBT和二极管,使得其SOA首次达到破纪录的最高极限。新元件的整体电特性都很优异,可以承受如关断和短路这样极端的工作条件。为此,针对给定的电压等级制定了其SOA工作能力的最新基准。 | M Rahimo A Kopta E Carroll | 2007 | 电力电子技术2007，41，3： | 2 |
| 8 | Management of humeral shaft fractures显示文摘 | Carroll EA Schweppe M Langfitt M | 2012 | Journal of the American Academy of Orthopaedic Surgeons2012，，07： | 2 |
| 9 | Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor显示文摘 | Korte M Carroll P Wolf E | 1995 | Proc Natl Acad Sci USA1995，92，： | 2 |
| 10 | Soluble CD14 and lipopolysaccharide -binding protein from bovine serum enable bacterial lipopolysacch- aride-mediated cytotoxicity and activation of bovine vascular endothelial cells in vitro显示文摘 | Yang Z Breider M A Carroll R C | | J Leukoc Biol0，199，： | 2 |
| 11 | Hybridoma fusion cell lines contain an aberrant kappa transcript显示文摘 | William L Carroll Elieen M Shoshana L | 1988 | Mole Immunol1988，10，25： | 1 |
| 12 | Synchronizing Chaotic Circuits显示文摘 | Carroll T L Pecora L M | 1991 | IEEE Transactions on Circuits and Systems1991，38，4： | 1 |
| 13 | Synchronization in chaotic systems显示文摘 | Pecora L M Carroll T L | 1990 | Phys Rev Lett1990，64，： | 1 |
| 14 | Immunosurveillance and Survivin-specific T-cell immunity in children with high-risk neuroblastoma显示文摘 | Coughlin C M Fleming M D Carroll R G | 2006 | J Clin Oncol2006，24，36： | 1 |
| 15 | Synchronization in the Chaotic Systems显示文摘 | PECORA L M CARROLL T L | 1990 | Physical Review Letters1990，64，8： | 1 |
| 16 | The effect of system frequency spectrum on commutation failure in HVDC inverter显示文摘 | Kristmundsson G M Carroll D P | 1990 | IEEE Trans on Power Delivery1990，5，2： | 1 |
| 17 | Influence of im- purity elements on electrochemical activity of aluminum activated by indium显示文摘 | Breslin C B Friery L P Carroll W M | 1993 | Corrosion1993，49，11： | 1 |
| 18 | Sedimentary record and climatic implications of recurrent deformation in the Tian Shan: Evidence from Mesozoic strata of the north Tarim,south Junggar,and Turpan basins, northwest China显示文摘 | Hendrix M S Graham S A Carroll A R | 1992 | Geological Society of America Bulletin1992，104，： | 1 |
| 19 | Common bile duct injuries during laparoscopic cholecystectomy that result in litigation 显示文摘 | Carroll BJ Birth M Phillps EH | 1998 | Surg Endosc1998，12，： | 1 |
| 20 | Stratigraphic classification of ancient lakes: balancing tectonic and climatic controls显示文摘 | Carroll A R Bohacs K M | 1999 | Geology1999，27，2： | 1 |
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