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| 1 | Non-alcoholic fatty liver disease and diabetes: From physiopathological interplay to diagnosis and treatment显示文摘Non-alcoholic fatty liver disease(NAFLD)is highly prevalent in patients with diabetes mellitus and increasing evidence suggests that patients with type 2diabetes are at a particularly high risk for developing the progressive forms of NAFLD,non-alcoholic steatohepatitis and associated advanced liver fibrosis.Moreover,diabetes is an independent risk factor for NAFLD progression,and for hepatocellular carcinoma development and liver-related mortality in prospective studies.Notwithstanding,patients with NAFLD have an elevated prevalence of prediabetes.Recent studies have shown that NAFLD presence predicts the development of type2 diabetes.Diabetes and NAFLD have mutual pathogenetic mechanisms and it is possible that genetic and environmental factors interact with metabolic derangements to accelerate NAFLD progression in diabetic patients.The diagnosis of the more advanced stages of NAFLD in diabetic patients shares the same challenges as in non-diabetic patients and it includes imaging and serological methods,although histopathological evaluation is still considered the gold standard diagnostic method.An effective established treatment is not yet available for patients with steatohepatitis and fibrosis and randomized clinical trials including only diabetic patients are lacking.We sought to outline the published data including epidemiology,pathogenesis,diagnosis and treatment of NAFLD in diabetic patients,in order to better understand the interplay between these two prevalent diseases and identify the gaps that still need to be fulfilled in the management of NAFLD in patients with diabetes mellitus. | Nathalie C Leite Cristiane A Villela-Nogueira Claudia R L Cardoso Gil F Salles | 2014 | World Journal of Gastroenterology2014，20，26： | 21 |
| 2 | Molecular approaches for spinal cord injury treatment显示文摘Injuries to the spinal cord result in permanent disabilities that limit daily life activities.The main reasons for these poor outcomes are the limited regenerative capacity of central neurons and the inhibitory milieu that is established upon traumatic injuries.Despite decades of research,there is still no efficient treatment for spinal cord injury.Many strategies are tested in preclinical studies that focus on ameliorating the functional outcomes after spinal cord injury.Among these,molecular compounds are currently being used for neurological recovery,with promising results.These molecules target the axon collapsed growth cone,the inhibitory microenvironment,the survival of neurons and glial cells,and the re-establishment of lost connections.In this review we focused on molecules that are being used,either in preclinical or clinical studies,to treat spinal cord injuries,such as drugs,growth and neurotrophic factors,enzymes,and purines.The mechanisms of action of these molecules are discussed,considering traumatic spinal cord injury in rodents and humans. | Fernanda Martins de Almeida Suelen Adriani Marques Anne Caroline Rodrigues dos Santos Caio Andrade Prins Fellipe Soares dos Santos Cardoso Luiza dos Santos Heringer Henrique Rocha Mendonça Ana Maria Blanco Martinez | 2023 | Neural Regeneration Research2023，18，1： | 3 |
| 3 | Recherches experimentales sur quelques proprietes thermiques des gaz-elements critiques et tensions de vapeur de l'oxyde de methyle 显示文摘 | Cardoso E Bruno A | 1923 | J Chim Phys1923，20，1： | 2 |
| 4 | A blind source separation technique using second order statistics 显示文摘 | Belouchrani A Abed-Meraim K Cardoso J-F | 1997 | IEEE Transactions on Signal Processing1997，45，： | 2 |
| 5 | Temperament and character dimensions and their relationship to major depression and panic disorder显示文摘 | MOCHCOVITCH MD NARD| AE CARDOSO A | 2012 | Rev Bras Psiquiatr2012，34，3： | 1 |
| 6 | Biocontrol of sheath blight by Trichoderma asperellum in tropical lowland rice 显示文摘 | de Fran~a S K S Cardoso A F Lustosa D C | 2015 | Agronomy for Sustainable Development2015，35，1： | 1 |
| 7 | A blind source separation technique based on second order statistics显示文摘 | A Belouchrani K A Merairn J-F Cardoso E Moulines | 1997 | reEF transactions on Signal Processing1997，45，2： | 1 |
| 8 | Preparation of activated carbons from cork waste by chemical activation with KOH显示文摘 | Carbalho P A Cardoso B P Pires J | 2003 | Carbon2003，41，14： | 1 |
| 9 | Electric power transmission at voltages of 1 000kV AC or ±600kV DC and above 显示文摘 | Manzoni G Annestrand S A Cardoso R etal | 1989 | Electra1989，，122： | 1 |
| 10 | A blind source separation technique using second-order Statistics 显示文摘 | BELOOUCHRANI A KARIM A M CARDOSO J F | 1997 | IEEE Trans Signal Process1997，45，2： | 1 |
| 11 | Distributions of indoor and outdoor air pollutants in Rio de Janeiro,Brazil:implications to indoor air quality in bayside offices显示文摘 | Brickus L S R Cardoso J N Neto F R D A | 1998 | Environ Sci Technol1998，32，： | 1 |
| 12 | Characterization study of gamma-irradiated,high melt-strength polypropylene,nuclear instruments & methods in physics research section B-beam显示文摘 | Lugao A B Cardoso ECL Lima LFCP | 2003 | Interactions with Materials and Atoma2003，208，4： | 1 |
| 13 | Uniform flow in a smooth open channel显示文摘 | Cardoso A H Graf W H Gust G | 1989 | Journal of Hydraulic Engineering ASCE1989，27，5： | 1 |
| 14 | Pro- calcitonin is useful in identifying bacteraemia among children with pneumonia显示文摘 | Nascimento-Carva Cardoso MR Barral A | 2010 | Scand J Infect Dis2010，42，9： | 1 |
| 15 | Blind Beamforming for Non-GaussianSignals 显示文摘 | Cardoso J F Souloumiac A | 1993 | Radar and Signal Processing (S0956-375X)1993，140，6： | 1 |
| 16 | A blind source separation technique using second-order statistics显示文摘 | Belouchrani A Abed-Meraim K Cardoso J F | | 0，，02： | 1 |
| 17 | Plantain and ba- nana starches:granule structural characteristics explain the differences in their starch degradation patterns 显示文摘 | Soares C A Peroni-Okita F H G Cardoso M B | 2011 | J Agric Food Chem2011，59，12： | 1 |
| 18 | ESO-ESMO 2nd internation- al consensus guidelines for advanced breast cancer (ABC2) 显示文摘 | Cardoso F Costa A Norton L | 2014 | Breast2014，23，5： | 1 |
| 19 | 显示文摘 | Carbalho P A Cardoso B P | 2003 | Carbon2003，41，14： | 1 |
| 20 | Validation of the determination of oxymetholone in human plasma analysis using gas chromatography-mass spectrometry Application to pharmacokinetic studies显示文摘 | Cardoso G R Marlice A Marques S | 2002 | Journal of Chromatography B2002，775，1： | 1 |
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