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| 1 | Probiotic effects on intestinal fermentation patterns in patients with irritable bowel syndrome显示文摘AIM: To determine whether Lactobacillus casei strain Shirota (Yakult ) can alter small intestinal bacterial overgrowth (SIBO), as tested by the lactulose breath test, and whether this is associated with changes in symptoms in irritable bowel syndrome (IBS). METHODS: 18 patients with IBS (Rome Ⅱ criteria), who showed an early rise in breath hydrogen with lactulose (ERBHAL), consumed 65 mL of Yakult daily for 6 wk. Lactulose breath test was repeated at the end of the treatment period. Symptoms were recorded daily using a 10 cm visual analogue scale. RESULTS: 14 patients completed the study, 9 (64%) had reversal of ERBHAL, with the median time of f irst rise in breath hydrogen increasing from 45 to 75 min (P = 0.03). There was no signifi cant improvement in the symptom score with probiotic therapy, except for wind (P=0.04). Patients commencing with at least moderate symptoms and who no longer had ERBHAL at the end of treatment, showed improvement in the overall symptoms scores [median fi nal score 5.3 (IQR3.9-5.9), 55% reduction; n=6] to a greater extent than those who had had persisting ERBHAL [final score 6.9 (5.0-7.0), 12% reduction; n = 5; P = 0.18]. CONCLUSION: Yakult is effective in altering fermentation patterns in the small bowel, consistent with reducing SIBO. The loss of ERBHAL was associated with reduced symptoms. The true interpretation of these fi ndings awaits a randomised, controlled trial. | Jacqueline S Barrett Kim EK Canale Richard B Gearry Peter M Irving Peter R Gibson | 2008 | World Journal of Gastroenterology2008，14，32： | 16 |
| 2 | 地震波数据揭示Casadia俯冲带“干”的Juan De Fuca板片显示文摘俯冲板片中的水(包括孔隙水和含水矿物中的结构水)对地球圈层之间的水循环、岛弧岩浆作用和地震活动等都有至关重要的影响。但是至今尚未综合研究过一个单一板片中水的含量、储存方式(孔隙水和结构水的相对比例)和分布(在沉积物、俯冲板片上地壳、下地壳和地幔中的分配)。 | Canales J P Carbotte S M Nedimovic M R Carton H 夏群科 | 2017 | 矿物岩石地球化学通报2017，36，6： | 2 |
| 3 | TiO2 - B nanowires as negative electrodea for rechargeable lithium batteries显示文摘 | Armstrong A R Armstrong G Canales J | 2005 | J Power Sources2005，146，12： | 1 |
| 4 | An integrated approach for shape and topology optimization of shell structures 显示文摘 | Ansola R Canales J Tarrago J A Rasmussen J | 2002 | Computers and Structures2002，80，56： | 1 |
| 5 | Ultrasound-assisted Method for the Determination of Chemical Oxygen Demand显示文摘 | CANALS A HERNANDEZ M D R | 2002 | Analytical and Bioanalytical Chemistry2002，374，6： | 1 |
| 6 | How disturbance by fossorial mammals alters N cycling in a California annual grassland显示文摘 | Canals R M Herman D J Firestone M K | 2003 | Ecology2003，84，： | 1 |
| 7 | Nanotubes with TiO2-B structure显示文摘 | Armstrong G Armstrong A R Canales J | 2005 | Chem Commun ( Cambridge U K)2005，，19： | 1 |
| 8 | On simultaneous shape and material layout optimization of shell structures 显示文摘 | Ansola R Canales J Tarrago J A Rasmussen J | 2002 | Structural and Multidisciplinary Optimization2002，24，3： | 1 |
| 9 | In Vitro morphogenic potential of differently aged Pinus radiate trees correlates with polyamines and DNA methylation levels显示文摘 | Fraga MF Rodriguez R Canal MJ | 2002 | Plant Cell Tiss Org Cult2002，70，2： | 1 |
| 10 | Experimental diabetes trea ted with ficus carica extract: effect on oxidative stress parame ters显示文摘 | Perez C Canal J R Torres M D | 2003 | ActaDiabetol2003，40，1： | 1 |
| 11 | Induction of a hypercoagulability state and endothelial cell activation by granulocyte colony -stimulating factor in peripheral blood stem cell donors 显示文摘 | Canales MA Arrieta R Gomez- Rioja R etal | 2002 | J Hematother Stem Cell Res2002，11，： | 1 |
| 12 | An integrat- ed approach for shape and topology optimization of shell struc- tures 显示文摘 | ANSOLA R CANALES J TARRAGO J A | 2002 | Computer and Structures2002，80，： | 1 |
| 13 | Annular wedge tympanoplasty:a variation of overlay myringoplasty显示文摘 | Albcra R Ferrero V Canale G | 1997 | Acta Otorhinolaryngol Ital1997，17，： | 1 |
| 14 | Autotoxicity in Lolium rigidum : Analyzing the role of chemically mediated interactions in annual plant populations 显示文摘 | CANALS R M EMETERIO L S PERALTA J | 2005 | Journal of Theoretical Biology2005，235，： | 1 |
| 15 | Photic maculopathy and iris dam-age in a psychotic patient显示文摘 | Ruiz-del-Rio N Moriche Carretero M Ortega Canales I RevillaAmores R Peralta Calvo JM | 2006 | Arch Soc Esp Oftalmol2006，81，3： | 1 |
| 16 | genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia显示文摘 | Canalle R Burim RV Tone LG | 2004 | Environ Mol Mutagen2004，43，2： | 1 |
| 17 | Aluminium impairs the glutamate-nitric oxide-cGMP pathway in cultured neurons and in rat brain in vivo: molecular mechanisms and implications for neuropathology 显示文摘 | Canales JJ Corbalan R Montoliu C | 2001 | J Inorg Biochem2001，87，12： | 1 |
| 18 | Polymorphisms of xenobiotic metabolizing enzymes and DNA repair genes and outcome in childhood acute lymphoblastic leukemia显示文摘 | DA SILVA SILVEIRA V CANALLE R SCRIDELI C A | 2009 | Leuk Res2009，33，7： | 1 |
| 19 | Osmotic dehydration of raspberries with vacuum pretreatment followed by microwave- vacuum drying显示文摘 | B6rquez R M Canales E R Redon J P | 2010 | Journal of Food Engineering2010，99，： | 1 |
| 20 | Lithium-ion intercalation into TiO2-B nanowires 显示文摘 | Armstrong A R Armstrong G Canales J Garcia R Bruce P G | 2005 | Advanced Materials2005，17，7： | 1 |
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