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| 1 | National natural capital accounting with the ecological footprint concept显示文摘 | Mathis Wackernagel Larry Onisto Patricia Bello Alejandro Callejas Linares Ina Susana López Falfán Jesus Méndez Garc??a Ana Isabel Suárez Guerrero Ma Guadalupe Suárez Guerrero | 1999 | Ecological Economics1999，，3： | 5 |
| 2 | Aplastic anemia and severe pancytopenia during treatment with peg-interferon,ribavirin and telaprevir for chronic hepatitis C显示文摘Telaprevir and Boceprevir are the first direct acting antivirals approved for chronic hepatitis C in combination with peg-interferon alfa and ribavirin.Pancytopenia due to myelotoxicity caused by these drugs may occur,but severe hematological abnormalities or aplastic anemia(AA) have not been described.We collected all cases of severe pancytopenia observed during triple therapy with telaprevir in four Spanish centers since approval of the drug in 2011.Among 142 cirrhotic patients receiving treatment,7 cases of severe pancytopenia(5%) were identified and three were consistent with the diagnosis of AA.Mean age was 59 years,five patients had compensated cirrhosis and two patients had severe hepatitis C recurrence after liver transplantation.Severe pancytopenia was diagnosed a median of 10 wk after the initiation of therapy.Three patients had pre-treatment hematological abnormalities related to splenomegaly.In six patients,antiviral treatment was interrupted at the onset of hematological abnormalities.Two patients died due to septic complications and one patient due to acute alveolar hemorrhage.The remaining patients recovered.Severe pancytopenia and especially AA,are not rare during triple therapy with telaprevir in patients with advanced liver disease.Close monitoring is imperative in this setting to promptly detect serious hematological disorders and to prevent further complications. | Sabela Lens Jose L Calleja Ana Campillo Jose A Carrion Teresa Broquetas Christie Perello Juan de la Revilla Zoe Marino Maria-Carlota Londono Jose M Sanchez-Tapias Alvaro Urbano-Ispizua Xavier Forns | 2015 | World Journal of Gastroenterology2015，21，17： | 4 |
| 3 | National natural capital accounting with the ecological footprint concept显示文摘 | Mathis Wackernagel Larry Onisto Patricia Bello Alejandro Callejas Linares Ina Susana López Falfán Jesus Méndez Garc??a Ana Isabel Suárez Guerrero Ma Guadalupe Suárez Guerrero | 1999 | Ecological Economics1999，，3： | 3 |
| 4 | Estimation of visceral fat is useful for the diagnosis of significant fibrosis in patients with non-alcoholic fatty liver disease显示文摘BACKGROUND Obesity is a risk factor for non-alcoholic fatty liver disease(NAFLD),although obese patients with NAFLD do not always develop significant fibrosis.The distribution of body fat could predict the risk of NAFLD progression.AIM To investigate the role of bioelectrical impedance-estimated visceral fat(VF)in assessing NAFLD severity.METHODS In this cross-sectional study,patients with biopsy-proven NAFLD were prospectively included.All patients underwent anthropometric evaluation,blood tests and bioelectrical impedance analysis.RESULTS Between 2017 and 2020,119 patients were included[66.4%male,56 years(SD 10.7),62.2%obese,61.3%with metabolic syndrome].Sixty of them(50.4%)showed significant fibrosis(≥F2)in liver biopsy.Age,VF and metabolic syndrome were associated with significant fibrosis(61 years vs 52 years,16.4 vs 13.1,73.3%vs 49.2%,respectively;P<0.001 for all).In the multivariate analysis,VF and age were independently associated with significant fibrosis(VF,OR:1.11,95%CI:1.02-1.22,P=0.02;age,OR:1.08,95%CI:1.03-1.12,P<0.01).A model including these variables showed and area under the receiver operating characteristic curve(AUROC)of 0.75,which was not inferior to transient elastography or NAFLD fibrosis score AUROCs.We developed a nomogram including age and VF for assessing significant fibrosis in routine practice.CONCLUSION VF is a surrogate marker of liver fibrosis in patients with NAFLD.Bioelectrical impedance analysis is an inexpensive and simple method that can be combined with age to guide patient referral when other resources may be unavailable. | Marta Hernández-Conde Elba Llop Carlos Fernández Carrillo Beatriz Tormo Javier Abad Luis Rodriguez Christie Perelló Marta López Gomez JoséLuis Martínez-Porras Natalia Fernández Puga Maria Trapero-Marugan Enrique Fraga Carlos Ferre Aracil JoséLuis Calleja Panero | 2020 | World Journal of Gastroenterology2020，26，42： | 2 |
| 5 | Aversion to acetaldehyde: differences in low-alcohol-drinking (UchA) and high-alcohol-drinking (UchB) rats显示文摘 | QUINTANILLA M E CALLEJAS O TAMPIER L | 2002 | Alcohol2002，26，： | 1 |
| 6 | The selective vasopressin V 1 a receptor agonist FE202158 reverses platelet activated factor(PAF)-induced hypotension,vascular leak,impaired tissue perfusion,and mortality in rats显示文摘 | Laporte R Wisniewska H Callejas L | | 0，，： | 1 |
| 7 | Effect of air-oxygen and argon-oxygen mixtures on dielectric barrier dischargedecomposition of toluene显示文摘 | Cabrera O G Callejas R L Valencia R | 2004 | Brazilian Journal of Physics2004，34，4： | 1 |
| 8 | TaqMan real–time PCR assay for detection of traces of Brazil nut(Bertholletia excelsa)in food products显示文摘 | Cruz S López–Calleja I M Alcocer M | 2013 | Food Control2013，33，5： | 1 |
| 9 | Development of the aerobic spoilage flora of chilled rabbit meat 显示文摘 | Jose M Rodriguez - Calleja Maria - htisa G L | 2005 | Meat Science2005，70，2： | 1 |
| 10 | Survey of undeclared allergenic pistachio(Pistacia vera)in commercial foods by hydrolysis probe real–time PCR显示文摘 | López–Calleja I M Cruz S González I | 2014 | Food Control2014，39，： | 1 |
| 11 | Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and-9 in fetal rat hepatocytes显示文摘 | Callejas NA Casado M Diaz-Guerra MJ Bosca L Martin-Sanz P | 2001 | Hepatology2001，33，4： | 1 |
| 12 | Ecological footprints of nations显示文摘 | Wackernagel M Onisto L Callejas L | 1997 | Toronto:International Council for Local Environmental Initiatives1997，，： | 1 |
| 13 | Periodically Rippled Graphene:Growth and Spatially Resolved Electronic Structure显示文摘 | de Parga A L V Calleja F Borca B | 2008 | Physical Review Letters2008，100，05： | 1 |
| 14 | Real - time TaqMan PCR for quantitative detection of cows' milk in ewes' milk mixtures 显示文摘 | Lo' pez - Calleja I Gonza' lez l Fajardo V | 2007 | Int Dairy J2007，17，： | 1 |
| 15 | The influence of microhardness on the sawability of pink porrino granite (Spain) 显示文摘 | DELGADO NS RODRIGUEZ R RIO A SARRIA ID CALLEJA L ARGANDONA VGR | 2005 | International Journal of Rock Mechanics and Mining Sciences2005，42，： | 1 |
| 16 | Origin of the colossal positive and negative thermalexpansion in Ag3显示文摘 | CALLEJA Mo GOODWIN A L DOVE M T | 2008 | J Phys:CondensMatter2008，20，： | 1 |
| 17 | National natural capital accounting with the ecological footprint concept显示文摘 | Wackernagel Mathis Onisto Larry Bello Patricia Callejas Linares Alejandra Susana López Falf ón Ina | 1999 | Ecological Economics1999，，3： | 1 |
| 18 | Measurements of the cross wind forces on trains显示文摘 | Baker C J Jones J Calleja F L | 2004 | Journal of Wind Engi- neering and Industrial Aerodynamics2004，92，1： | 1 |
| 19 | Periodically rippled graphene:growth and spatially resolved electronic structure显示文摘 | de Pargn A L V Calleja F Borca B | 2008 | Phys Rev Lett2008，100，05： | 1 |
| 20 | Structure and Mechanical Properties of Polyethylene Fullerene Composites 显示文摘 | Balta Calleja F J Giri L Asano T | 1996 | Materials Scienece1996，31，： | 1 |
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