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| 1 | Assessment of vascular invasion in gastric cancer: A comparative study显示文摘AIM: To evaluate and compare detection of lymphatic and blood vessel invasion (LVI and BVI) by hematox-ylin-eosin (HE) and immunohistochemistry (IHC) in gastric cancer specimens, and to correlate with lymph node status. METHODS: IHC using D2-40 (a lymphatic endothelial marker) and CD34 (a pan-endothelial marker) was performed to study LVI and BVI in surgical specimens froma consecutive series of 95 primary gastric cancer cases. The results of the IHC study were compared with the detection by HE using McNemar test and kappa index. The morphologic features of the tumors and the presence of LVI and BVI were related to the presence of lymph node metastasis. A χ2 test was performed to obtain associations between LVI and BVI and other prognostic factors for gastric cancer. RESULTS: The detection rate of LVI was considerably higher than that of BVI. The IHC study identified eight false-positive cases and 13 false-negative cases for LVI, and 24 false-positive cases and 10 false-negative cases for BVI. The average Kappa value determined was moderate for LVI (k=0.50) and low for BVI (k=0.20). Both LVI and BVI were statistically associated with the presence of lymph node metastasis (HE: P=0.001, P=0.013, and IHC: P=0.001, P=0.019). The mor-phologic features associated with LVI were location of the tumor in the distal third of the stomach (P=0.039), Borrmann's macroscopic type (P=0.001), organ inva-sion (P=0.03) and the depth of tumor invasion (P=0.001). The presence of BVI was related only to the depth of tumor invasion (P=0.003). CONCLUSION: The immunohistochemical identification of lymphatic and blood vessels is useful for increasing the accuracy of the diagnosis of vessel invasion and for predicting lymph node metastasis. | Letícia Trivellato Gresta Ismael Alves Rodrigues-Júnior Lúcia Porto Fonseca de Castro Geovanni Dantas Cassali Mnica Maria Demas lva-res Cabral | 2013 | World Journal of Gastroenterology2013，19，24： | 8 |
| 2 | The corrosion resistance of hot dip galvanized steel pretreated with his functional silanes modified with microsiliea显示文摘 | Montemor M F Cabral A M Zheludkevich M L etal | 2006 | Surface and Coatings Technology2006，200，9： | 1 |
| 3 | Prediction of the solubility of aromatic compounds from Brazilian roasted coffee (2- methylpyrazine; 2-furfurylalcohol; 2,5-dimethylpyrazine; y-butyrolactone and 2-furfurylacetate) in SC-CO显示文摘 | DE OLIVEIRA A L EBERLIN M N CABRAL F A | 2009 | J Chem Eng Jpn2009，42，4： | 1 |
| 4 | Down-regulation of factor IXa in thefactor Xase complex by protein Z-dependent protease inhibitor显示文摘 | Heeb M J Cabral K M Ruan L | 2005 | JBiol Chem2005，280，33： | 1 |
| 5 | Intra-Industry Trade Expansion and Employment Reallocation between Sectors and Occupa- tions 显示文摘 | CABRAL M SILVA J | 2006 | Review of World Economics2006，，3： | 1 |
| 6 | Resuscitation fromhemorrhagic shock with Hydroxyethyl Starch and coagulation changes 显示文摘 | Cabrales P Tsa AG Intalieglietta M | 2007 | Shock2007，28，4： | 1 |
| 7 | Changes in the trophic level of Portuguese landings and fish market price variation in the last decades显示文摘 | BAETA F JOSE COSTA M CABRAL H | 2009 | Fisheries Research2009，97，3： | 1 |
| 8 | The influence of cul-ture conditions on mycelial structure and eellulase production by Trichoderma reese/Rut C-30显示文摘 | Domingues F C Queiroz J A Cabral J M S | 2000 | Enzyme and Microbial Technolo-gy2000，26，5： | 1 |
| 9 | The learning curve,predation,antitrust,and welfare显示文摘 | RIORDAN M H | 1997 | The Journal of Industrial Economics1997，45，2： | 1 |
| 10 | The body-mass index,airflow obstruction,dyspnea,and exercise capacity index in chronic obstructive pulmonary disease显示文摘 | Celli BR Cote CG Marin JM Casanova C Montes de Oca M Mendez RA Pinto Plata V Cabral HJ | 2004 | N Engl J Med2004，350，10： | 1 |
| 11 | Sympathetic neuronal surviral induced by retinal trophic factors 显示文摘 | Reis R A Cabral de Silra M C Loureiro dos Santos N E | 2002 | J Neurobiol2002，50，1： | 1 |
| 12 | Phytosterols : Applications and recovery methods 显示文摘 | Fernandes P Cabral J M S | 2007 | Bioresource Technology2007，98，12： | 1 |
| 13 | Monopoly Pricing with Network Externalities 显示文摘 | Cabral L M B Salant D J Woroch G A | 1999 | International Journal of Industrial Organization1999，17，2： | 1 |
| 14 | The Corrosion Resistance of Hot Dip Galvanised Steel and AA2024-T3 Pre-treated with Bis- Te- trasulfide Solutions Doped with Ce(NO3)3显示文摘 | CABRAL A M TRABELSI W SERRA R | 2006 | Corrosion Science2006，48，11： | 1 |
| 15 | Phytosterols: applications and recovery methods 显示文摘 | FERNANDES P CABRAL J M | 2007 | Bioresource Technology2007，98，12： | 1 |
| 16 | Packaging Waste Recycling in Europe: Is the Industry Paying for It?显示文摘 | Cruz N F 'Ferreira S Cabral M | 2014 | Waste Manarement2014，34，： | 1 |
| 17 | Isovolemic exchange transfusion with increasing concentrations of low oxygen affinity hemoglobin solution limits oxygen delivery due to vasoconstriction显示文摘 | Cabrales P Tsai AG lntaglietta M | 2008 | Am J Physiol Heart Cite Physiol2008，295，5： | 1 |
| 18 | Factors associated wilh return to work following a hand injury:a qualilative/quantitalive approach显示文摘 | Cabral L H Sampaio R F Figueiredo 1 M | 2010 | Rev Bras Fisiotcr2010，14，2： | 1 |
| 19 | A comparison of proper orthngonal decomposition and Mote Carlo simulation of wind pressure data显示文摘 | Rocha M M Cabral S V S Riera J D | 2000 | Journal of Wind Engineering Industrial Aerodynamics2000，84，： | 1 |
| 20 | Rheumatic manifestations of Bartonella infection in 2 children 显示文摘 | Al-Matar M J Petty R E Cabral D A | 2002 | J Rheumatol2002，29，： | 1 |
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