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| 1 | 昆虫诱集装置--马氏网的类型与使用显示文摘马氏网是一种常用的诱集昆虫的装置,本文介绍了马氏网的主要类型,结构差异,使用要点等,并简单回顾了关于马氏网使用效果的研究。 | 吴琼 C.van Achterberg 陈学新 | 2016 | 应用昆虫学报2016，53，3： | 16 |
| 2 | 采用3D影像融合CT全肝容积灌注成像提高肝转移瘤的检出和特征显示显示文摘评价CT全肝容积灌注技术对肝转移瘤的检出及显示转移瘤特征的可行性。对20例病人进行平扫及静脉注射对比剂后的11次全肝容积螺旋CT扫描。 | M.R.Meijerink J.H.T.M.van Waesberghe L.van der Weide P.van den Tol S.Meijer C.van Kuijk 胡涛 | 2008 | 国际医学放射学杂志2008，31，A06： | 8 |
| 3 | Second to fourth digit ratio (2D:4D) and testosterone in men显示文摘Aim: To investigate the relationship between 2D:4D and testosterone in men attending an infertility clinic and men drawn from the general population. Methods: Data on 2D:4D and testosterone from two samples were collected: (1) 43 men attending an infertility clinic, and (2) 51 men drawn from the general population without regard to fertility. Results: In sample (1) there were negative associations between 2D:4D and testicular function, and men with lower 2D:4D in their right compared to left hand had higher testosterone levels than men with higher 2D:4D in their right compared to left hand. Sample (2) showed no significant associations between 2D:4D or side differences in 2D:4D and testosterone. Conclusion: Adult levels of testosterone may be related to aspects of 2D:4D in samples which contain men with compromised testicular function, but not in men from normative samples. Associations between 2D:4D and fertility-associated traits probably arise from early organisational effects of testosterone rather than from activational effects of current testosterone. (Asian J Androl 2004 Sep; 6: 211-215) | J.T.Manning S.Wood E.Vang J.Walton P.E.Bundred C.van Heyningen D.I.Lewis-Jones | 2004 | Asian Journal of Andrology2004，6，3： | 7 |
| 4 | 中国优茧蜂亚科研究概况及已知种名录(膜翅目:茧蜂科)显示文摘本文对我国优茧蜂亚科 Euphorinae (除悬茧蜂属 Meteorus Haliday以外 )的分类研究情况作了总结 ,并列出我国已知种名录 (2 6属 1 54种 ) | 陈学新 何俊华 C.van Achterberg 马云 | 2000 | Entomotaxonomia2000，22，1： | 4 |
| 5 | Review article: blood platelet number and function in chronic liver disease and cirrhosis显示文摘 | P.WITTERS K.FRESON C.VERSLYPE K.PEERLINCK M.HOYLAERTS F.NEVENS C.VAN GEET D.CASSIMAN | 2008 | Alimentary Pharmacology & Therapeutics2008，，11： | 4 |
| 6 | High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis显示文摘Background:Schistosomiasis,a parasitic disease also known as bilharzia and snail fever,is caused by different species of flatworms,such as Schistosoma mansoni(S.mansoni).Thioredoxin glutathione reductase(TGR)from S.mansoni(SmTGR)is a well-characterized drug target for schistosomiasis,yet no anti-SmTGR compounds have reached clinical trials,suggesting that therapeutic development against schistosomiasis might benefit from additional scaffolds targeting this enzyme.Methods:A high-throughput screening(HTS)assay in vitro against SmTGR was developed and applied to a diverse compound library.SmTGR activity was quantified with ThioGlo®,a reagent that fluoresces upon binding to the free sulfhydryl groups of the reaction product GSH(reduced glutathione).Results:We implemented an HTS effort against 59,360 synthetic compounds.In the primary screening,initial hits(928 or 1.56%)showing greater than 90%inhibition on SmTGR activity at a final concentration of 10μM for each compound were identified.Further tests were carried out to confirm the effects of these hits and to explore the concentration-dependent response characteristics.As a result,74 of them(0.12%)representing 17 chemical scaffolds were confirmed and showed a great concentration-dependent inhibitory trend against SmTGR,including structures previously shown to be lethal to schistosomal growth.Of these,two scaffolds displayed a limited structure-activity relationship.When tested in cultured larvae,39 compounds had cidal activity in 48 h,and five of them killed larvae completely at 3.125μM.Of these,three compounds also killed adult worms ex vivo at concentrations between 5μM and 10μM.Conclusion:These confirmed hits may serve as starting points for the development of novel therapeutics to combat schistosomiasis. | Ting Li Peter D.Ziniel Pan-qing He Valerie P.Kommer Gregory J.Crowther Min He Qing Liu Wesley C.Van Voorhis David L.Williams Ming-Wei Wang | 2015 | Infectious Diseases of Poverty2015，4，1： | 3 |
| 7 | Differences between the floras of the North and South Moluccas (Indonesia)显示文摘The north and south Moluccas (Indonesia)have very different geotectonic origins and,due to that,a difference in flora is to be expected.The north Moluccas moved westwards along the north coast of New Guinea to their present position,the south Moluccas moved north from Australia.On the other hand,a comparable climate in both areas and (partial)submergence during tectonic movement may have equalized both floras.Collection data from Naturalis Biodiversity Center on 1559species in 121families treated in Flora Malesiana were collected for the Moluccas,Sulawesi,and Western New Guinea (latitudes 9.2°S and 5.6~N and longitudes 118.8°E and 141°E)and georeferenced.Species Distribution Models (SDMs)were made,based on least correlated climate and edaphic variables,using only those species that were present in 5or more grid cells of 5-arc minutes and models were tested for deviation from random.Both areas differ significantly and share only 50%-65% of their species.The 348 significant SDMs differ much less,though still significantly,sharing 91%of the species.Despite strong climatic and edaphic similarities between the North and South Moluccas,they differ greatly in species composition,which is in support of geotectonic reconstructions.The differences between the North and South Moluccas suggest that the continuous dispersal barriers and tectonic backgrounds have influenced their current flora. | Anne L.J.Rutgrink Michael Visser Peter C.van Welzen | 2018 | Journal of Systematics and Evolution2018，56，6： | 2 |
| 8 | 太阳紫外辐射增加对人类健康的影响显示文摘伴随着平流层臭氧耗损,UV-B辐射增加对人类健康将可能有很大的影响。潜在的危险包括眼病、皮肤癌和传染病发生率的增加。对某些形响(例如皮肤癌)的危害性的定量估计是可能的,而对另外一些影响(例如传染病),由于缺乏足够的资料,定量估计是不可能的。在实验系统中显示,UV辐射损伤眼角膜和眼的晶状体。生命期长期积累的高剂量UV-B辐射是与皮质型及后囊下型白内障危害相联系的几个原因之一。臭氧耗损对白内障的影响已做了估计,但仍十分不确定。这些估计指出当臭氧减少l%白内障的增加0.5%。免疫系统的某些成分存在于皮肤中,使得免疫系统易受UV辐射的影响。在动物身上的试验表明,UV照晒能降低对皮肤癌、传染物和其它抗原的免疫反应,重复照晒还可能导致免疫反应丧失。抑制免疫既可以局部出现在太阳照射皮肤处,也可系统性地出现在非太阳照射部位。在人体上的研究也指出,UV-B辐射能抑制某些免疫反应的产生,并可能造成免疫功能系统性的改变。这些免疫影响,相对于人传染病的重要性是未知的。然而,在传染病对人的健康是主要威胁的地区以及在免疫功能已受到抑制的人群中,UV-B引起的免疫抑制的损害增加可能是很大的。在敏感的白皮肤人群中,生命期UV-B累积照晒对非黑瘤皮肤癌(NM-SC)的发展是个关键的危险因素。这一知识已允许我们对臭氧损失引起的NMSC发生率增长的危险性作定量估计。使用来源于动物试验和人流行性病学的资料,我们估计,平流层臭氧1%持续性的减少将会导致 NMSC发生率增加约 2%。UV-B照晒与黑瘤皮肤癌之间的关系更为少知,而且它似乎与 NMSC的那种关系根本不同,不同点在于,它实际上不是生命期积累剂量的一个函数,但可能与高剂量照晒(如晒伤)的多次累积作用相联系。流行性病学资料指出,随着强日光照晒(即,晒伤)事件的增加,黑色瘤危险性将增加,尤其是儿童。然而,这些曝晒和黑瘤之间的关系如何模型化以使得由于臭氧耗损造成的黑瘤增加估计得更准确,这点是没有把握的。 | Janice D.Longstreth Frank.R.deGruijl Margaret L.Kripke Yukio Takizawa Jan C.van der Leun 王寅辉 | 1995 | 人类环境杂志1995，24，3： | 2 |
| 9 | Oral Pulsed Dexamethasone Therapy in Early Rheumatoid Arthritis显示文摘 | ERIC‐JAN A.KROOT A. MARGRIETHUISMAN JENDéVAN ZEBEN JACQUES M.G.W.WOUTERS HENK C.VAN PAASSEN | 2006 | Annals of the New York Academy of Sciences2006，，1： | 1 |
| 10 | Services Tradability Trade Liberalization and Foreign Direct Invest-ment显示文摘 | Marrewijk C.van Stibora J A.de Vaal | | 0，，： | 1 |
| 11 | Topical 5‐fluorouracil treatment of anal intraepithelial neoplasia in human immunodeficiency virus‐positive men显示文摘 | O.Richel U.Wieland H.J.C.De Vries N.H.Brockmeyer C.Van Noesel A.Potthoff J.M.Prins A.Kreuter | 2010 | British Journal of Dermatology2010，，6： | 1 |
| 12 | Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment显示文摘 | B.Winblad K.Palmer M.Kivipelto V.Jelic L.Fratiglioni L.‐O.Wahlund A.Nordberg L.B?ckman M.Albert O.Almkvist H.Arai H.Basun K.Blennow M.De Leon C.DeCarli T.Erkinjuntti E.Giacobini C.Graff J.Hardy C.Jack A.Jorm K.Ritchie C.Van Duijn P.Visser R.C.Petersen | 2004 | Journal of Internal Medicine2004，，3： | 1 |
| 13 | Allergic rhinitis management pocket reference 2008*显示文摘 | J.Bousquet J.Reid C.Van Weel C.Baena Cagnani G. W.Canonica P.Demoly J.Denburg W. J.Fokkens L.Grouse K.Mullol K.Ohta T.Schermer E.Valovirta N.Zhong T.Zuberbier | 2008 | Allergy2008，，8： | 1 |
| 14 | The Relation between Parental Personality and Observed Parenting:The Moderating Role of Preschoolers' Effortful Control显示文摘 | A.Karreman C.van Tuijl M.A.van Aken | | 0，，03： | 1 |
| 15 | Ovarian cancer prediction in adnexal masses using ultrasound‐based logistic regression models: a temporal and external validation study by the IOTA group显示文摘 | D.Timmerman B.Van Calster A. C.Testa S.Guerriero D.Fischerova A. A.Lissoni C.Van Holsbeke R.Fruscio A.Czekierdowski D.Jurkovic L.Savelli I.Vergote T.Bourne S.Van Huffel L.Valentin | 2010 | Ultrasound Obstet Gynecol2010，，： | 1 |
| 16 | The role of CnTI‐SonoVue in the diagnosis of ovarian masses with papillary projections: a preliminary study显示文摘 | A. C.Testa D.Timmerman C.Exacoustos E.Fruscella C.Van Holsbeke D.Bokor D.Arduini G.Scambia G.Ferrandina | 2007 | Ultrasound Obstet Gynecol2007，，5： | 1 |
| 17 | MR imaging of hepatocellular carcinoma: Relationship between lesion size and imaging findings, including signal intensity and dynamic enhancement patterns显示文摘 | Indra C.van den Bos Shahid M.Hussain Roy S.Dwarkasing Wim C.J.Hop Pieter E.Zondervan Robert A.de Man Jan N.M.IJzermans Craig W.Walker Gabriel P.Krestin | 2007 | J. Magn. Reson. Imaging2007，，： | 1 |
| 18 | Myocardial function in infarcted and remote regions early after infarction in man: Assessment by magnetic resonance tagging and strain analysis显示文摘 | J. TimMarcus Marco J. W.G?tte Albert C.van Rossum Joost P. A.Kuijer Robert M.Heethaar LeonAxel Cees A.Visser | 2005 | Magn Reson Med2005，，5： | 1 |
| 19 | Mechanical Consequences of Bone Loss in Cancellous Bone显示文摘 | J. C.Van Der Linden J.Homminga J. A. N.Verhaar H.Weinans | 2009 | J Bone Miner Res2009，，3： | 1 |
| 20 | Anti‐C1q autoantibodies in murine lupus nephritis显示文摘 | L. A.TROUW M. A.SEELEN R.VISSEREN J. M. G. J.DUIJS H.BENEDIKTSSON E.DE HEER A.ROOS C.VAN KOOTEN M. R.DAHA | 2003 | Clinical & Experimental Immunology2003，，1： | 1 |
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