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| 1 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 2 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 3 | Factors for Successful E- Government Adoption: A Conceptual Framework 显示文摘 | Kumar V Mukerji B Butt I | 2007 | The Electronic Journal of E - Government2007，5，1： | 1 |
| 4 | Pore geometry in woven fiber structures: 0 degrees/90 degrees plain- weave cloth layup preform 显示文摘 | LEE S B STOCK S R BUTTS M D | 1998 | Journal of Materials Research1998，13，5： | 1 |
| 5 | Music Modulates Behaviour of Pre- mature Infants Following Heel Lance显示文摘 | Butt M L Kisilevsky B S | 2000 | Can J Nurs Res2000，，： | 1 |
| 6 | Particle size, particle size distribution and related measurements of supported metal catalyst显示文摘 | Matyi R J Schwartz L H Butt J B | 1987 | Catal Rev Sci Eng1987，29，1： | 1 |
| 7 | Force measurements with the atomic force microscope:Technique, interpretation and applications 显示文摘 | Butt H-J Cappella B Kappl M | 2005 | Surface Science Reports2005，59，16： | 1 |
| 8 | Management of unstable thoracolumbar spinal injuries by posterior short segment spinal fixation显示文摘 | Butt MF Farooq M Mir B | 2007 | Int Orthop2007，31，2： | 1 |
| 9 | An evaluation of the impact of model structure on hydrological modeling uncertainty for streamflow simulation显示文摘 | Butts M B Payne J T Kristensen M | 2004 | Journal of Hydrology2004，298，： | 1 |
| 10 | Management of unstablethoracolum-bar spinal injuries by posterior short segmentspinal fixation显示文摘 | Butt MF Farooq M Mir B | 2007 | Int Orthop2007，31，2： | 1 |
| 11 | Influence of the lipophilicity of an ion-pairing reagent on metal ion separation using ion-pair HPLC显示文摘 | Riaz M Butt S B | 2006 | Journal of Liquid Chromatography and Related Technologies2006，29，20： | 1 |
| 12 | Management of unstable thoracolum-bar spinal injuries by posterior short segment spinal fixation显示文摘 | Butt MF Farooq M Mir B | 2007 | IntOrthop2007，31，2： | 1 |
| 13 | Optimizing the highway lifetime by improving the self healing capacity of asphalt显示文摘 | Butt A A Birgisson B Kringos N | 2012 | Proc-Soc Behav Sci2012，48，： | 1 |
| 14 | Perineal reconstruction after extra-levator abdominoperineal excision (eLAPE): a systematic review 显示文摘 | Butt HZ Salem MK Vijaynagar B | 2013 | Int J Colorectal Dis2013，28，11： | 1 |
| 15 | Experimental and modeling study of kinetics and selectivity in the oxidation of a poly ( a - olefin) lubricant 显示文摘 | Koht C S Butt J B | 1995 | Ind Eng Chem Res1995，34，2： | 1 |
| 16 | Simplified fuzzy-logic-based MTPA speed control of IPMSM drive 显示文摘 | Casey B Butt Ashraful Hoque M Azizur Rahman M | 2004 | IEEE Transactions on Industry Applications2004，40，： | 1 |
| 17 | Do Economic Fac- tors Influence Stock Returns? A Firm and Industry Level Anal- ysis 显示文摘 | Butt B Z Rehman K U Khan M A | 2010 | African Journal of Business Management2010，4，5： | 1 |
| 18 | Deubiquitinating enzymes as novel anticancer targets 显示文摘 | Nicholson B Marblestone JG Butt TR | 2007 | Future Oncol2007，3，2： | 1 |
| 19 | Kinetics of the desulfurization of thiophene:reactions of thiophene and butene显示文摘 | Lee H C Butt J B | 1977 | Journal of Catalysis1977，49，3： | 1 |
| 20 | Management of unsta- ble thoracolumbar spinal injuries by posterior short seg- ment spinal fixation 显示文摘 | Butt MF Farooq M Mir B | 2007 | Int Orthop2007，31，2： | 1 |
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