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| 1 | Endoscopy-based management decreases the risk of postoperative recurrences in Crohn's disease显示文摘AIM: To investigate whether an endoscopy-based management could prevent the long-term risk of postoperative recurrence.METHODS: From the pathology department database, we retrospectively retrieved the data of all the patients operated on for Crohn's disease(CD) in our center(1986-2015). Endoscopy-based management was defined as systematic postoperative colonoscopy(median time after surgery = 9.5 mo) in patients with no clinical postoperative recurrence at the time of endoscopy. RESULTS: From 205 patients who underwent surgery, 161 patients(follow-up > 6 mo) were included. Endoscopic postoperative recurrence occurred in 67.6%, 79.7%, and 95.5% of the patients, respectively 5, 10 and 20 years after surgery. The rate of clinical postoperative recurrence was 61.4%, 75.9%, and 92.5% at 5, 10 and 20 years, respectively. The rate of surgical postoperative recurrence was 19.0%, 38.9% and 64.7%, respectively, 5, 10 and 20 years after surgery. In multivariate analysis, previous intestinal resection, prior exposure to anti-TNF therapy before surgery, and fistulizing phenotype(B3) were postoperative risk factors. Previous perianal abscess/fistula(other perianal lesions excluded), were predictive of only symptomatic recurrence. In multivariate analysis, an endoscopy-based management(n = 49/161) prevented clinical(HR = 0.4, 95%CI: 0.25-0.66, P < 0.001) and surgical postoperative recurrence(HR = 0.30, 95%CI: 0.13-0.70, P = 0.006).CONCLUSION: Endoscopy-based management should be recommended in all CD patients within the first year after surgery as it highly decreases the long-term risk of clinical recurrence and reoperation. | Anne-Laure Boucher Bruno Pereira Stéphanie Decousus Marion Goutte Felix Goutorbe Anne Dubois Johan Gagniere Corinne Borderon Juliette Joubert Denis Pezet Michel Dapoigny Pierre J Déchelotte Gilles Bommelaer Anthony Buisson | 2016 | World Journal of Gastroenterology2016,22,21: | 3 |
| 2 | Serine protease inhibitors:novel therapeutic targets for stroke显示文摘 | Vivien D Buisson A | 2000 | J Cereb Blood Flow Metab2000,20,: | 1 |
| 3 | Generalized granuloma annulare: remission during treatment of HIV infection显示文摘 | Jacobi D Rivollier C Buisson H | 2005 | Ann Dermatol Veneral2005,132,3: | 1 |
| 4 | Generalized granuloma annulare :remission during treatment of HIV infection 显示文摘 | Jacobi D Rivollier C Buisson H | 2005 | Ann Dermatol Venereol2005,132,3: | 1 |
| 5 | Storage of New Zealand Jack mackerel (Trachurus novaezelandiae) in ice: chemical, microbiological and sensory assessment显示文摘 | RYDER J M BUISSON D H SCOTT D N | 1984 | Journal of Food Science1984,49,14: | 1 |
| 6 | Allosteric modulation of neuronal nicotinic acetylcholine receptors 显示文摘 | Buisson B Bertrand D | 1998 | J Physiol Paris1998,92,2: | 1 |
| 7 | National culture and R&D and marketing integration mechanisms in new product devel- opment: a cross-cultural study between singapore and new zealand显示文摘 | Garrett T C Buisson D H Yap C M | 2009 | Industrial Marketing ManagAement2009,38,3: | 1 |
| 8 | Eva1uation of new diagnostic technologies:bronchoalveolar lavage and the diagnosis of ventilator-associated pneumonia显示文摘 | Brun Buisson C Guyatt G H | 1994 | Crit Care Med1994,22,: | 1 |
| 9 | Spectrum of Practice in the diagnosis of nosoeomial Pneumoniain Patients requiring meehanical ventilation in Europe anintensive care units 显示文摘 | Koulenti D Lisboa T Brun Buisson C | 2009 | Crit-CareMed2009,37,8: | 1 |
| 10 | Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2显示文摘 | Lafite P Dijols S Buisson D | 2006 | Bioorganic Med Chem Lett2006,16,10: | 1 |
| 11 | A bridge crosses the active-site canyon of the Epstein-Barr vivus nuclease with DNase and RNase activities显示文摘 | Buisson M Géoui T Folt D | 2009 | J Mol Biol2009,391,4: | 1 |
| 12 | Slurry hydmgenation in acontinuous flow for pharmaceutical application 显示文摘 | Buisson B Donegan S Wray D | 2009 | ChemistryToday2009,27,6: | 1 |
| 13 | Action of temper- ature on spermatogenesis, sperm production and fertility of the boar 显示文摘 | MAZZARRI G D MESNIL D BUISSON F | 1968 | Anita Reprod Sci1968,13,: | 1 |
| 14 | Slurry hydrogenation in a continuous flow reactor for pharmaceutical application 显示文摘 | BUISSON B STEVE D WRAY D | 2009 | Chemistry Today2009,27,2: | 1 |
| 15 | Allosteric modulation of ligand-gated ion channels显示文摘 | Hogg RC Buisson B Bertrand D | 2005 | Biochem Pharmacol2005,70,9: | 1 |
| 16 | National Culture and R&Dand Marketing Integration Mechanisms in New Product Development显示文摘 | Garrett T C Buisson D H Yap C M | 2009 | Industrial Marketing ManagAement2009,38,3: | 1 |
| 17 | Synthesis of 5-acyl-3,4-dihydropyrimidine-2-thiones via solvent-free,solution-phase and solid-phase biginelli procedures显示文摘 | Comas H Buisson D A Najman R Kozielsk F Rousseau B Lopez R | | 0,,: | 1 |
| 18 | Slurry hydrogenation in a continuous flow reactor for pharmaceutical application显示文摘 | Buisson B Donegan S Wray D | 2009 | Chemistry Today2009,27,6: | 1 |
| 19 | Evidence of type I and type H transforming growth factor-beta receptors in central nervous tissues: changes induced by focal cerebral ischemia 显示文摘 | Bernaudin M Buisson A | 1998 | J Neurochen1998,70,6: | 1 |
| 20 | Success through customer - driven new product development: a comparison of US and new zealand small entrepreneurial high technology firms显示文摘 | SOUDER W E BUISSON D GARRETT T | 1997 | Journal of Product Innovation Management1997,14,6: | 1 |