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| 1 | Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients. | Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski | 2017 | World Journal of Hepatology2017，9，12： | 11 |
| 2 | Operating experience with modulation of the pacific HVDC inter-tie显示文摘 | Cresap R L Scott D N | 1978 | IEEE Trans on Power Apparatus andSystems1978，97，4： | 2 |
| 3 | Adipocyte iron regulates adiponectin and insulin sensitivity显示文摘 | Gabrielsen J Scott Gao Yan Simcox Judith A Huang Jingyu Thorup David Jones Deborah Cooksey Robert C Gabrielsen David Adams Ted D Hunt Steven C Hopkins Paul N Cefalu William T McClain Donald A | 2012 | EN2012，，10： | 2 |
| 4 | Multiferroic and magnetoelectric materials显示文摘 | Eerenstein W Mathur N D Scott J F | 2006 | Nature2006，42，17： | 1 |
| 5 | Foliage litter qua Comparison across North lity and annual American for- est sites显示文摘 | SCOTT N A net N mineral BINKLEY D | 1997 | Oecologia1997，111，2： | 1 |
| 6 | Multiferroic and Magnetoelectric Materials显示文摘 | Eerenstein W Mathur N D Scott J F | 2006 | Nature2006，442，： | 1 |
| 7 | Land-use change: effects on soil carbon, nitrogen and phosphorus pools and fluxes in three adjacent ecosystems 显示文摘 | Ross D J Tate K R Scott N A | 1999 | Soil Biology and Biochemis try1999，31，： | 1 |
| 8 | Foliage litter quality and annual net N mineralization: comparison across North American forest sites 显示文摘 | Scott N A Binkley D | 1997 | Oecologia1997，111，2： | 1 |
| 9 | Rationale of the Knee Society clinical rating system显示文摘 | INSALL J N DORR L D SCOTT R D | 1989 | Clin Or- thop Relat Res1989，，248： | 1 |
| 10 | Low temperature mechanical properties of scandium-modified Al-Zn-Mg-Cu alloys显示文摘 | SENKOY O N MIRACLE D B MILMAN Y V SCOTT J M LOTSKO D V SIRKO A I | 2002 | Materials Science Forum2002，，： | 1 |
| 11 | Stem-like cells in bone sarcomas: implications for tumorigenesis显示文摘 | Gibbs C P Kukekov V G Reith J D Tchigrinova O Suslov O N Scott E W | 2005 | Neoplasia2005，7，： | 1 |
| 12 | Stress-strain be- havior of concrete confined by overlapping hoops at low and high strain rates 显示文摘 | Scott B D Park R Priestley M J N | 1982 | ACI Journal1982，79，1： | 1 |
| 13 | Stress-Strain Behavior of Concrete Confine by Overlapping Hoops at Low and High Strain Rates显示文摘 | Scott B D Park R Priestley M J N | 1982 | ACI Journal1982，79，2： | 1 |
| 14 | Rationale of the Knee Societyclinical rating system显示文摘 | Insall J N Dorr L D Scott R D | 1989 | Clin Orthop Relat Res1989，248，： | 1 |
| 15 | Multiferroic and magnetoelectric materials显示文摘 | Eerenstein W Mathur N D Scott J F | 2006 | Nature2006，442，7104： | 1 |
| 16 | Stress-strain behavior of concrete confined by overlapping hoops at low and high strain rates显示文摘 | Scott B D Park R Priestley M J N | 1982 | ACI Journal1982，79，1： | 1 |
| 17 | Improving water flood recovery of viscous crude oils by chemical control显示文摘 | Scott G R Collins H N Flock D L | 1965 | J Can Petrol Technol1965，4，4： | 1 |
| 18 | Multiferroic and magnetoelectric materials 显示文摘 | Eerenstein W Mathur N D Scott J F | 2006 | Nature2006，442，710： | 1 |
| 19 | Shear strength and stress-strain behaviour of Athabasca oil sand at ele- vated temperatures and pressures显示文摘 | Agar J G Morgenstem N R Scott J D | 1987 | Canadian Geotechni- cal Journal1987，24，1： | 1 |
| 20 | Use of load control to regulate vohage on distribution networks with embedded generation 显示文摘 | Scott N C Atkinson D J Morrell J E | 2002 | IEEE Trans on Power Systems2002，17，2： | 1 |
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