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| 1 | Characteristics of Clostridium difficile infection in patients hospitalized with myelodysplastic syndrome or acute myelogenous leukemia显示文摘AIM To evaluate factors associated with Clostridium difficile infection (CDI) and outcomes of CDI in the myelodysplastic syndrome(MDS) and acute myeloid leukemia (AML) population.METHODS After IRB approval,all MDS/AML patients hospitalized at the University of Maryland Greenebaum Comprehensive Cancer Center between August 2011 and December 2013 were identified.Medical charts were reviewed for demographics,clinical information,development of CDI,complications of CDI,and mortality.Patients with CDI,defined as having a positive stool PCR done for clinical suspicion of CDI,were compared to those without CDI in order to identify predictors of disease.A t-test was used for comparison of continuous variables and chisquare or Fisher's exact tests were used for categorical variables,as appropriate.RESULTS Two hundred and twenty-three patients (60.1% male,mean age 61.3 years,13% MDS,87% AML) had 594 unique hospitalizations during the study period.Thirtyfour patients (15.2%) were diagnosed with CDI.Factors significantly associated with CDI included lower albumin at time of hospitalization (P < 0.0001),prior diagnosis of CDI (P < 0.0001),receipt of cytarabine-based chemotherapy (P = 0.015),total days of neutropenia (P = 0.014),and total days of hospitalization (P = 0.005).Gender (P = 0.10),age (P = 0.77),proton-pump inhibitor use (P = 0.73),receipt of antibiotics (P = 0.66),and receipt of DNA hypomethylating agent-based chemotherapy (P = 0.92) were not significantly associated with CDI.CONCLUSION CDI is common in the MDS/AML population.Factors significantly associated with CDI in this population include low albumin,prior CDI,use of cytarabine-based chemotherapy,and prolonged neutropenia.In this study,we have identified a subset of patients in which prophylaxis studies could be targeted. | Kamini Shah Bryan F Curtin Christopher Chu Daniel Hwang Mark H Flasar Erik von Rosenvinge | 2017 | World Journal of Clinical Oncology2017，8，5： | 3 |
| 2 | 2004英国高血压学会高血压治疗指南(BHS-IV):概要显示文摘在高血压领域,不断出现的新证据已日益受到关注。例如:血压可作为心血管疾病的一个危险因素;改进生活方式对于预防和治疗高血压的重要意义;不同类型药物的有效性和安全性;高危高血压患者包括糖尿病患者的治疗;心血管疾病总体危险性评估的重要性以及使用他汀类药物所获得的额外益处。 | Bryan Williams Neil R Poulter Peter S Sever Morris J Brown Mark Davis Gordon T McInnes John F Potter 邱洪 | 2004 | 英国医学杂志中文版2004，7，5： | 2 |
| 3 | Climate Variability and the Frequency of Extreme Temperature Events for Nine Sites across Canada: Implications for Power Usage 显示文摘 | Colombo F Andrew David Etkin Bryan W Karney | 1999 | Journal of Climate1999，12，： | 1 |
| 4 | Hazards and critical control points of street-vended chat, a regionally popular food in Pakistan显示文摘 | Bryan F L Teufel P | 1992 | J Food Prot1992，55，9： | 1 |
| 5 | No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics显示文摘 | Sanders Alan R Duan Jubao Levinson Douglas F Shi Jianxin He Deli Hou Cuiping Burrell Gregory J Rice John P Nertney Deborah A Olincy Ann Rozic Pablo Vinogradov Sophia Buccola Nancy G Mowry Bryan J Freedman Robert Amin Farooq Black Donald W | 2008 | The American Journal of Psychiatry2008，，4： | 1 |
| 6 | Time VariabilityoftheEarth’s Gravity Field:Hydrologicaland OceanicEffectsandtheirPossibleDetectionUsingGRACE显示文摘 | WahrJ Molenaar M Bryan F | 1998 | JournalofGeophysical Research:Solid Earth (1978-2012)1998，103，30： | 1 |
| 7 | A fuzzy multi-objective programming for optimization of fire station locations through genetic algorithms显示文摘 | YANG Li-li BRYAN F J YANG Shuang-hua | 2007 | European Journal of Operational Research2007，181，2： | 1 |
| 8 | A fuzzymulti-objective programming for optimization of fire stationlocations through genetic algorithms 显示文摘 | YANG Lili BRYAN F J YANG Shuanghua | 2007 | European Jour-nal of Operational Research2007，，181： | 1 |
| 9 | Time Variability of theEarth’s Gravity Field:Hydrological and Oceanic Effectsand Their Possible Detection Using GRACE 显示文摘 | Wahr J Molevarar M Bryan F | 1998 | Journal ofGeophysical Research1998，103，30： | 1 |
| 10 | The Frankliniella occidentalis (Pergande) complex in California (Thysanoptera:Thripidae)显示文摘 | Bryan D E Smith R F | 1956 | Univ Ca Ent Pub1956，10，： | 1 |
| 11 | Logistics planning under uncertainty for disposition of radioactive wastes 显示文摘 | List George F Wood Bryan Turnquist Mark A Nozick Linda K Jones Dean A Lawton Craig R | 2006 | Computers and Operations Research2006，33，3： | 1 |
| 12 | Numerical Simu lation of the North Atlantic Ocean at 1/10 Degree显示文摘 | Simth R D Maltrud M E Bryan F O | 2000 | Journal of Physical Oceanogr2000，，30： | 1 |
| 13 | The effect of CO2 availability on the growth, iron oxidation and CO,-fixation rates of pure cultures of Leptospirillum Jerriphilum and Acidithiobacillus Jerrooxidans 显示文摘 | BRYAN C G DAVIS-BELMAR C S van WYK N FRASER M K DEW D RAUTENBACH G F HARRISON | 2012 | Biotechnology and Bioengineering2012，109，7： | 1 |
| 14 | Difference in radar returns from ice-covered North Slope lakes 显示文摘 | Weeks W F Fountain A G Bryan M L | 1978 | Journal of Geophysical Research1978，83，8： | 1 |
| 15 | Time-variability of the Earth's gravity field:hydrological and oceanic effects and their possible detection using GRACE显示文摘 | Wahr J Molenaar M Bryan F | | 0，，12： | 1 |
| 16 | A prospective ran- domised controlled trial of nutritional supplementation in malnourished elderly in the community: clinical and health economic outcomes 显示文摘 | Edington J Barnes R Bryan F | 2004 | Clinical Nutrition2004，23，2： | 1 |
| 17 | DNA probe technology for rapid detection of Haemophilus influenzae in clinical specimens 显示文摘 | Malouin F Bryan LE Shewciw P | 1988 | J Clin Microbiol1988，26，10： | 1 |
| 18 | Inflation and the Distribution of Price Changes显示文摘 | Bryan M F Cecchetti S G | 1999 | Review of Economics and Statistics1999，81，2： | 1 |
| 19 | A randomized trial of vertebroplasty for osteoporotic spinal fractures显示文摘 | David F Kallmes MD Bryan A | | 0，，361： | 1 |
| 20 | Time variability of the Earth’s gravity field:hydrological and oceanic effects and their possible detection using GRACE显示文摘 | WAHR J MOLENAAR M BRYAN F | 1998 | Journal of Geophysical Research Atmospheres1998，103，30： | 1 |
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