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	题名	作者	年代	出处	被引量
1	Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis显示文摘During sepsis,neutrophil activation induces endothelial cell(EC)dysfunction partly through neutrophil extracellular trap(NET)release.The triggering receptor expressed on myeloid cell-1(TREM-1)is an orphan immune receptor that amplifies the inflammatory response mediated by Toll-like receptor-4(TLR4)engagement.Although the key role of TLR4 signaling in NETosis is known,the role of TREM-1 in this process has not yet been investigated.Here,we report that TREM-1 potentiates NET release by human and murine neutrophils and is a component of the NET structure.In contrast,pharmacologic inhibition or genetic ablation of TREM-1 decreased NETosis in vitro and during experimental septic shock in vivo.Moreover,isolated NETs were able to activate ECs and impair vascular reactivity,and these deleterious effects were dampened by TREM-1 inhibition.TREM-1 may,therefore,constitute a new therapeutic target to prevent NETosis and associated endothelial dysfunction.	Amir Boufenzer Kevin Carrasco Lucie Jolly Benjamin Brustolin Elisa Di-Pillo Marc Derive Sébastien Gibot	2021	Cellular & Molecular Immunology2021，18，2：	9
2	Wound healing under the effect of iodine cadexomer in rats显示文摘	Ester Ver?nica Brustolin Thelma Larocca Skare Paulo Afonso Nunes Nassif Maria de Lourdes Pessole Biondo-Sim?es Manoel Alberto Prestes Laila Marim Ozono Camila Ercolin Ramos	2012	Acta cirflrgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia2012，27，12：	1
3	A 12 to 24 weeks pilot study of sertraline treatment in obese women binge eaters显示文摘	Leombruni P Piero A Brustolin A		0，，03：	1
4	Wound healing under the effect of iodine cadexomer in rats 显示文摘	Brustolin EV Skare TL Nassif PA	2012	27 (12): 874-8792012，27，12：	1
5	A 12 to 24 weeks pilot study of sertraline treatment in obese women binge eaters显示文摘	Leombruni P Piero A Brustolin A		0，，03：	1
6	Genetics of homocysteine metabolism and associated disorders显示文摘	Brustolin S Giugliani R Fé1ix TM		0，，01：	1
7	Bilat- eral suhthalamic nucleus stimulation in advanced Parkinson's disease:five year follow-up显示文摘	Gervais- Bernard H Xie- Brustolin J Mertens P	2009	J Neurol2009，256，2：	1
8	Genetics of homocys- teine metabolism and associated disorders 显示文摘	Brustolin S Giugliani R F61ix TM	2010	Braz J Med Biol Res2010，43，1：	1
9	Genetics of homocysteine metabolism and associated disorders显示文摘	BRUSTOLIN S GIUGLIANI R FLIX T M	2010	Braz J Med Biol Res2010，43，1：	1
10	Genetics of homoeysteine metabolism and associated disorders显示文摘	Brustolin S Giugliani R Félix T M	2010	Braz J Med Biol Res2010，43，1：	1
11	Recent devel- opments toward the use of tungsten as armour material in plasma facing components显示文摘	Mitteau R Missiaen J M Brustolin P	2007	Fusion Engineering and Design2007，82，：	1
12	Genetics of homocysteine metabolism and associated disorders显示文摘	Brustolin S Giugliani R Felix TM	2010	Braz J Med Biol Res2010，43，：	1
13	Genetics of homocysteine metabolism and associated disorders显示文摘	Brustolin R Giugliani TM Félix	2010	Brazilian Journal of Medical and Biological Research2010，43，：	1
14	Bilateral subthalamic nucleus stimulation in advanced Parkinson's disease: five year follow- up显示文摘	Gervais-Bernard H Xie - Brustolin 1 Mertens P	2009	1 Neurol2009，256，2：	1
15	Recent developments toward the use of tungsten as armour mate- rial in plasma facing components显示文摘	Mittaeu R Missiean J M Brustolin P	2007	Fusion Engineering and Design2007，82，：	1
16	A 12 to 24 weeks pilot study of sertraline treatment in obese women binge eaters显示文摘	Leombruni P Piero A Brustolin A	2006	Hum Psychopharmacol2006，21，3：	1
17	A 12 to 24 weeks pilot study of sertraline treatment in obese women binge eaters显示文摘	Leombruni P Piero A Brustolin A	2006	Hum Psyehopharmaeol2006，21，3：	1
18	Genetics of homocysteine metabo- lism and associated disorders 显示文摘	Brustolin R Giugliani TM F61 ix	2010	Brazilian Journal of Mediealand Biological Research2010，43，：	1
19	Genetics of homocysteine metabolism and associated disorders 显示文摘	Brustolin S Giugliani R Felix TM	2010	Braz J Med Biol Res2010，43，1：	1
20	Genetics of homocysteine metabolism and associated disorders 显示文摘	Brustolin S Giugliani R F61ix TM	2010	Braz J Med Biol Res2010，43，1：	1

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