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| 1 | Qualitative Analysis of Xinyue Capsules(心悦胶囊)by High-Performance Liquid Chromatography:Preliminary Evaluation of Drug Quality in A Sino-Austrian Joint Study显示文摘Objective:To develop a reliable method to assess the stability of Xinyue Capsules(心悦胶囊) containing Panax quinquefofius saponins according to European quality standards.Methods:An efficient high-performance liquid chromatography ultraviolet(HPLC-UV) method was established to analyse six main ginsenosides(Rb1,Rb2,Rc,Rd,Re and Rg1) in six different batches(120 capsules/batch) from the same lot of Xinyue Capsules and in one batch measured six times within one day.The six ginsenosides were separated on a Hypersil BDS-C_(18) column(3 μm,100 mm×3 mm) at a flow rate of 0.5 mL/min.Gradient elution was performed using a mobile phase gradient of acetonitrile-water modified with 0.01%formic acid.The HPLC chromatograms were analyzed with TC data comparison' using Lab Solutions software.Results:The HPLC peaks were identified by comparing their retention times(Rg1:23.44 min,Re:23.77 min,Rb1:35.24 min,Rc:36.18 min,Rb2:38.55 min and Rd:40.88 min) with those of the standards under the same chromatographic conditions,which showed similar results among the samples of six different batches and among the samples from one batch detected six times within one day.Conclusions:Xinyue Capsules have good drug intra-day consistency at room temperature and exhibit a consistent quality between different batches.This study established a reliable method to assess the stability of Xinyue Capsules,which is suitable for further qualitative analysis and may assist in promoting the safe and effective use of Chinese herbal medicine. | 薛梅 杨琳 史大卓 Christian Radauer Heimo Breiteneder 马燕 | 2015 | Chinese Journal of Integrative Medicine2015，21，10： | 2 |
| 2 | Molecular and biochemical classification of plant-derived food allergens显示文摘 | Heimo Breiteneder PhD and Christof Ebner MD | 2000 | Journal of allergy and clinical immunology2000，106，1： | 1 |
| 3 | Genetic engineer- ing of allergens: future therapeutic products 显示文摘 | Ferreira F Wallner M Breiteneder H | 2002 | Int Arch Aller- gy Immunol2002，128，3： | 1 |
| 4 | Molecular characterization of Api gl, the major allergen of celery (Apium graveolens), and its im- munological and structural relationships to a group of 17-kDa tree pollen allergens 显示文摘 | BREITENEDER H HOFFMANN-SOMMERGRUBER K O'RI- ORDAIN G | 1995 | European Journal of Biochemistry1995，233，2： | 1 |
| 5 | Molecular properties of food allergens显示文摘 | BREITENEDER H MILLS E | 2005 | Journal of Allergy and Clinical Immunology2005，115，1： | 1 |
| 6 | Genetic engineering of allergen:future therapeutic products显示文摘 | FERRREIRA F WALLNER M BREITENEDER H | 2002 | Int Arch Allergy Immunol2002，128，： | 1 |
| 7 | Podoplanin, a no- vel 43 kD membrane protein of glomerular epithelial cells , is down- regulated in puromycin nephrosis 显示文摘 | Breiteneder S Matsui K Soleiman A | 1997 | Am J Pathol1997，151，4： | 1 |
| 8 | Molecular and immunological characteristics of latex allergens显示文摘 | Breiteneder H Scheiner O | 1998 | Int Arch Allergy Immunol1998，116，2： | 1 |
| 9 | Plant food allerges--structural and functional aspects of allergenicity 显示文摘 | Breiteneder H Clare mills E N | 2005 | Biotechnology ad- vances2005，23，6： | 1 |
| 10 | The Naturalness of English as a European Lingua Franca: The Case of the ' Third Person-s' 显示文摘 | Breiteneder A | 2005 | Vienna English Working Papers2005，，14： | 1 |
| 11 | Rapid production of recombinant allergen in Nicotiana benthamiana and their impact on diagnosis and therapy 显示文摘 | BREITENEDER H KREBITZ M WIEDERMANN U | 2001 | Int Arch Allergy Immunol2001，124，13： | 1 |
| 12 | Molecular and biochemical classification of plantderived food allergens显示文摘 | BREITENEDER H EBNER C | 2000 | Journal of Allergy and Clinical Immunology2000，106，： | 1 |
| 13 | Molecular and biochemical classification of plant-derived food allergens显示文摘 | Breiteneder H Ebner C | | 0，，： | 1 |
| 14 | Molecular and biochemical classi? cation of plant-derived food allergens 显示文摘 | Breiteneder H Ebner C | 2000 | J Allergy Clin Immunol2000，106，1： | 1 |
| 15 | The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydruphobic lig- ands 显示文摘 | Radauer C Lackner P Breiteneder H | 2008 | BMC Evolutionary Biology2008，8，1： | 1 |
| 16 | Identification of allergens in fruits and vegetables:Ig E crossreactivities with the important birch pollen allergens Bet v 1 and Bet v 2(birch profilin)显示文摘 | EBNER C HIRSCHWEHR R BAUER L BREITENEDER H VALENTA R KRAFT D | 1995 | Journal of Allergy and Clinical Immunology1995，95，： | 1 |
| 17 | Intrapericardial lymphangioma with podoplanim immunohistochemical characterization of lymphatic endothelial cells显示文摘 | Sinzelle E Van Huyen JP Breiteneder | 2000 | Histopathology2000，37，1： | 1 |
| 18 | Evolutionary distance from human homologs reflects allergenicity of animal food proteins显示文摘 | Jenkins JA Breiteneder H Mills EN | | 0，，06： | 1 |
| 19 | Food allergy and itsrelevance to industrial food proteins显示文摘 | Millsenc Breiteneder H | 2005 | Biotech Adance2005，，23： | 1 |
| 20 | A classification of plant food allergens显示文摘 | Breiteneder H Radauer C | 2004 | J Allergy Clin hnmunol2004，113，5： | 1 |
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