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	题名	作者	年代	出处	被引量
1	Chemotherapy plus percutaneous radiofrequency ablation in patients with inoperable colorectal liver metastases显示文摘AIM:To access the efficacy of chemotherapy plus radiofrequency ablation(RFA)as one line of treatment in inoperable colorectal liver metastases.METHODS:Eligible patients were included in three PhaseⅡstudies.In the first study percutaneous RFA was used first followed by 6 cycles of 5-fluorouracil,leucovorin and irinotecan combination(FOLFIRI)(adjunctive chemotherapy trial).In the other two,chemotherapy(FOLFIRI or 5-fluorouracil,leucovorin and oxaliplatin combination)up to 12 cycles was used first with percutaneous RFA offered to responding patients (primary chemotherapy trials).RESULTS:Thirteen patients were included in the adjunctive chemotherapy trial and 17 in the other two.At inclusion they had 1-4 liver metastases(up to 6.5 cm in size).Two patients died during chemotherapy.All patients in the adjunctive chemotherapy trial and 44%in the primary chemotherapy studies had their metastases ablated.Median PFS and overall survival in the adjunctive study were 13 and 24 mo respectively while in the primary chemotherapy studies they were 10 and 21 mo respectively.Eighty one percent of the patients had tumour relapse in at least one previously ablated lesion.CONCLUSION:Chemotherapy plus RFA in patients with low volume inoperable colorectal liver metastases seems safe and relatively effective.The high local recurrence rate is of concern.	Joseph Sgouros James Cast Krishna K Garadi Maria Belechri David J Breen John RT Monson Anthony Maraveyas	2011	World Journal of Gastrointestinal Oncology2011，3，4：	4
2	Analysis of the performance of dynamic multicast routing algorithms显示文摘	Cho J Breen J	1999	Computer Communications1999，22，7：	2
3	Improved selectivity in the toluene alkylation reaction through understanding and optimising the process variables显示文摘	BREEN J P BURCH R KULKARNI M	2007	Appl Catal A: General2007，316，12：	1
4	Quaternary ammonium compounds inhibit and reduce the attachment of viable Salmonella typhimurium to poultry tissues显示文摘	BREEN P J COMPADRE C M FIFER E K	1995	J Food Sci1995，60，6：	1
5	Fitting a woven-cloth model to a curved surface: mapping algorithms显示文摘	AONO M BREEN D E WOZNY M J	1994	Computer Aided Design1994，26，4：	1
6	Geometrically deformed models:A method for extracting closed geometric models from volume data显示文摘	J V Miller D E Breen	1991	Computer Graphics1991，25，4：	1
7	Concrete capacity design (CCD) approach for fastening to concrete显示文摘	Fuchs W Eligehausen R Breen J E	1995	ACI Structural Journal1995，92，1：	1
8	-141 C del/ins polymorphism of the dopamine receptor 2 gene is associated with schizophrenia in a British population 显示文摘	Breen G Brown J Maude S	1999	Am J Med Genet1999，88，4：	1
9	General Practitioners'experiences of bereavement care and their educationalsupport needs:a qualitative study显示文摘	Moira O ’ Connor Lauren J Breen	2014	BMC Med Educ2014，14，1：	1
10	Improved selectivity in the toluene alkylation reaction through understanding and optimising the process variables 显示文摘	Breen J P Burch R Kulkarni M	2007	Applied Catalysis A General2007，316，1：	1
11	Safety and tolerability of gatifloxacin,an advanced-generation 8-methoxy fluoroquinolone显示文摘	Breen J Skuba K Grasela D	1999	J Resp Dis1999，20，：	1
12	Behavior of post - tensioned girder anchorage zones显示文摘	Stone W C Breen J E	1984	PCI Journal1984，29，1：	1
13	Mechanistic aspects of the selective reduction of NO by propene over alumina and silver-alumina catalysts显示文摘	F C Meunier J P Breen V Zuzaniuk	1999	Journal of Catalysis1999，，187：	1
14	The registry of the International Society for Heart Lung Transplantation:eleventh official report-1994显示文摘	Hosenpud J D Novick R J Breen T J	1994	J Heart Transplant1994，13，4：	1
15	Tuberculosis and HIV co-infection:a practical therapeutic approach显示文摘	Breen RA Swaden L Ballinger J	2006	Drugs2006，66，18：	1
16	Mechanistic differences in the selective reduction of NO by propene over cobalt- and silver-promoted alumina catalysts: kinetic and in situ DRIFTS study显示文摘	F C Meunier V Zuzaniukl J P Breen	2000	Catalysis Today2000，，59：	1
17	, Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence显示文摘	Mattiek RP Breen C Kimber J	2009	Cochrane Database Syst Rev2009，，00：	1
18	Hydration of tr/calcium aluminate (C3A) in presence and absence of gypsum- studied by Raman spectroscopy and X-ray diffraction显示文摘	BLACK S BREEN G YARWOOD J	2006	Journal of Materials Chemistry2006，，16：	1
19	A fresh look atmanagement of depression How to choose and use the newer antidepressant drugs 显示文摘	Breen R Mccormac R J	2002	Postgrad Med2002，112，3：	1
20	Placenta accreta, increta,and percreta: a survey of 40 cases 显示文摘	Breen J L Neubecker R Gyegori C A	1977	Obstet Gynecol1977，49，1：	1

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