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| 1 | Chronic constipation in hemiplegic patients显示文摘AIM: To assess the prevalence of bowel dysfunction in hemiplegic patients, and its relationship with the site of neurological lesion, physical immobilization and pharmacotherapy. METHODS: Ninety consecutive hemiplegic patients and 81 consecutive orthopedic patients were investigated during physical motor rehabilitation in the same period, in the same center and on the same diet. All subjects were interviewed ≥ 3 mo after injury using a questionnaire inquiring about bowel habits before injury and at the time of the interview. Patients’ mobility was evaluated by the Adapted Patient Evaluation Conference System. Drugs considered for the analysis were nitrates, angiogenic converting enzyme (ACE) inhibitors, calcium antagonists, anticoagulants, antithrombotics, antidepressants, anti-epileptics. RESULTS: Mobility scores were similar in the two groups. De novo constipation (OR = 5.36) was a frequent outcome of the neurological accident. Hemiplegics showed an increased risk of straining at stool (OR: 4.33), reduced call to evacuate (OR: 4.13), sensation of incomplete evacuation (OR: 3.69), use of laxatives (OR: 3.75). Logistic regression model showed that constipation was significantly and independently associated with hemiplegia. A positive association was found between constipation and use of nitrates and antithrombotics in both groups. Constipation was not related to the site of brain injury. CONCLUSION: Chronic constipation is a possible outcome of cerebrovascular accidents occurring in 30% of neurologically stabilized hemiplegic patients. Its onset after a cerebrovascular accident appears to be independent from the injured brain hemisphere, and unrelated to physical inactivity. Pharmacological treatment with nitrates and antithrombotics may represent an independent risk factor for developing chronic constipation. | F Bracci D Badiali P Pezzotti G Scivoletto U Fuoco L Di Lucente A Petrelli E Corazziari | 2007 | World Journal of Gastroenterology2007，13，29： | 15 |
| 2 | Inelastic Response of R/C Structures with Viscoelastic Braces显示文摘 | LOBO R F BRACCI J M SHEN K L | 1993 | Earthquake Spectra1993，9，3： | 1 |
| 3 | Type Ⅰ interferons as vaccine adjuvants against infectious diseases and cancer 显示文摘 | Bracci L La Sorsa V Belardelli F | 2008 | Expert Rev Vaccines2008，7，3： | 1 |
| 4 | Human CD4^+ T cell clones produce and release nerve growth factor and express high - affinity nerve growth factor receptors 显示文摘 | Lambiase A Bracci - Laudiero L Bonini S | 1997 | J Allergy Clin Immunol1997，100，3： | 1 |
| 5 | A model of the Rabies virus glycoprotein active site 显示文摘 | RUSTICI M BRACCI L LOZZI L | 1993 | Biopolymers1993，33，6： | 1 |
| 6 | Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression B-cell and T-cell homeostatic proliferation and specifictumor in filtration显示文摘 | Bracci L Moschella F Sestili P | 2007 | Clin Cancer Res2007，13，2： | 1 |
| 7 | Type Ⅰ IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus显示文摘 | Bracci L Canini L Venditti M | 2006 | Vaccine2006，24，： | 1 |
| 8 | Strong CD8^+ T cell antigenicity and immunogenicity of large foreign proteins incorporated in HIV - 1 VLPs able to induce a Nef - dependent activation/maturation of dendritic cells显示文摘 | Sistign A Bracci L Valentini N | 2011 | Vaccine2011，29，2011： | 1 |
| 9 | Human bone marrowmesenchymal stem cells and chondrocytes promote and/or suppressthe in vitro proliferation of lymphocytes stimulated by interleu-kins2,7 and 5显示文摘 | Bocelli-Tyndall C Bracci L Schaeren S | 2009 | Ann Rheum Dis(2009，68，8： | 1 |
| 10 | Matrix metalloproteinase-9 and myeloperoxidase expression: quantitative analysis by antigen immanohistochemistry in a model of transient focal cerebral ischemia 显示文摘 | Maier C M Hsieh L Y Bracci P | 2004 | Stroke2004，35，： | 1 |
| 11 | Seismic evaluation of column-to-beam strength ratios inreinforced concrete frames显示文摘 | Dooley K L Bracci J M | 2001 | ACI Structural Journal2001，98，6： | 1 |
| 12 | Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression,B-cell and T-cell homeostatic proliferation,and specific tumor infiltration显示文摘 | Bracci L Moschella F Sestili P | 2007 | Clin Cancer Res2007，13，： | 1 |
| 13 | Seismic evaluation of column- to- beam strength ratios in reinforced concrete frames显示文摘 | Dooley k L Bracci J M | 2001 | ACi Strcutural Jouranl2001，98，6： | 1 |
| 14 | Seismic evaluation of column-to-beam strength ratios in reinforced concrete frames 显示文摘 | Dooley K L Bracci J M | 2001 | ACI Structural Journal2001，98，6： | 1 |
| 15 | Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression,B- cell and T cell homeostatic proliferation, and specific tumor infiltration显示文摘 | Bracci L Moschella F Sestili P | 2007 | Clin Cancer Res2007，13，2： | 1 |
| 16 | Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against Influenza virus in mice and affects antigen capture at mucosal level显示文摘 | Bracci L Canini L Puzelli S | 2005 | Vaccine2005，23，23： | 1 |
| 17 | Atomic Effects in the Determination of Nuclear Cross Sections of Astrophysical Interest 显示文摘 | Fiorentini G Melezhik V S | 1990 | Nucl Phys1990，513，： | 1 |
| 18 | NGF modulates CGRP synthesis in human B - lymphocytes: a possible anti - inflammatory action of NGF? 显示文摘 | Bracci - Laudiero L Aloe L Buanne P | 2002 | J Neuroimmunol2002，123，12： | 1 |
| 19 | Therapeutic activity of an engineered synthetic killer antiidiotypic antibody fragment against experimental mucosal and systemic candidiasis显示文摘 | Polonelli L Magliani W Conti S Bracci L Lozzi L Neri P | 2003 | Infect Immun2003，71，： | 1 |
| 20 | A model of the rabies virus glycoprotein active site显示文摘 | Rustici M Bracci L Lozzi L | 1993 | Biopolymers1993，33，： | 1 |
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