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| 1 | Favorable lifestyle before diagnosis associated with lower risk of screen-detected advanced colorectal neoplasia显示文摘AIM: To investigate the association between adherence to health recommendations and detection of advanced colorectal neoplasia(ACN) in colorectal cancer(CRC) screening.METHODS: A total of 14832 women and men were invited to CRC screening, 6959 in the fecal immunochemical test arm and 7873 in the flexible sigmoidoscopy arm. These were also sent a self-reported lifestyle questionnaire to be completed prior to their first CRC screening. A lifestyle score was created to reflect current adherence to healthy behaviors in regard to smoking, body mass index, physical activity, alcohol consumption and food consumption, and ranged from zero(poorest) to six(best). Odds ratios(ORs) and 95%CIs were calculated using multivariable logistic regression to evaluate the association between the single lifestyle variables and the lifestyle score and the probability of detecting ACN.RESULTS: In all 6315 women and men completed the lifestyle questionnaire, 3323(53%) in the FIT arm and 2992(47%) in the FS arm. This was 89% of those who participated in screening. ACN was diagnosed in 311(5%) participants of which 25(8%) were diagnosed with CRC. For individuals with a lifestyle score of two, three, four, and five-six, the ORs(95%CI) for the probability of ACN detection were 0.82(0.45-1.16), 0.43(0.28-0.73), 0.41(0.23-0.64), and 0.41(0.22-0.73), respectively compared to individuals with a lifestyle score of zero-one. Of the single lifestyle factors, adherence to non-smoking and moderate alcohol intake were associated with a decreased probability of ACN detection compared to being a smoker or having a high alcohol intake 0.53(0.42-0.68) and 0.63(0.43-0.93) respectively.CONCLUSION: Adopted healthy behaviors were inversely associated with the probability of ACN detection. Lifestyle assessment might be useful for risk stratification in CRC screening. | Markus D Knudsen Thomas de Lange Edoardo Botteri Dung-Hong Nguyen Helge Evensen Chloé B Steen Geir Hoff Tomm Bernklev Anette Hjartaker Paula Berstad | 2016 | World Journal of Gastroenterology2016，22，27： | 3 |
| 2 | Psychological effects of colorectal cancer screening: Participants vs individuals not invited显示文摘AIM To investigate the possible long-term psychological harm of participating in colorectal cancer(CRC)screening in Norway.METHODS In a prospective, randomized trial, 14294 participants(aged 50-74 years) were invited to either flexible sigmoidoscopy(FS) screening, or a faecal immunochemical test(FIT)(1:1). In total, 4422 screening participants(32%) completed the questionnaire, which consisted of the Hospital Anxiety and Depression Scale and the SF-12, a generic health-related quality of life(HRQOL) measurement, when invited to screening and one year after the invitation. A control group of 7650 individuals was invited to complete the questionnaire only, at baseline and one year after, and 1911(25%) completed the questionnaires.RESULTS Receiving a positive or negative screening result and participating in the two different screening modalities did not cause clinically relevant mean changes in anxiety, depression or HRQOL after one year. FS screening, but not FIT, was associated with an increased probability of being an anxiety case(score ≥ 8) at the one-year follow-up(5.6% of FS participants transitioned from being not anxious to anxious, while 3.0% experienced the reverse). This increase was moderately significantly different from the changes in the control group(in which the corresponding numbers were 4.8% and 4.5%, respectively), P = 0.06. CONCLUSION Most individuals do not experience psychological effects of CRC screening participation after one year, while FS participation is associated with increased anxiety for a smaller group. | Benedicte Kirk?en Paula Berstad Edoardo Botteri Linn Bernklev Badboni El-Safadi Geir Hoff Thomas de Lange Tomm Bernklev | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 3 | Impact on survival of the number of lymph nodes removed in patients with nodenegative gastric cancer submitted to extended lymph node dissection显示文摘 | Biffi R Botteri E Cenciarelli S | 2011 | Eur J Surg Oncol2011，37，4： | 1 |
| 4 | Smoking and colorectal canc- er: a meta-analysis 显示文摘 | Botteri E Iodice S Bagnardi V | 2008 | JAMA2008，300，23： | 1 |
| 5 | Generating signals of drug-adverse effects from prescription databases and application to the risk of arrhythmia associated with antibacterials 显示文摘 | Corrao G Botteri E Bagnardi V | 2005 | Pharmacoepidemiol Drug Saf2005，14，1： | 1 |
| 6 | Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long term potentiation显示文摘 | Luthi A Van der Putten H Botteri FM | 1997 | J Neurosci1997，17，12： | 1 |
| 7 | Smoking and colorectal cancer:a meta-analysis 显示文摘 | Botteri E Iodice S Bagnardi V | 2008 | JAMA2008，300，23： | 1 |
| 8 | Critical illness myopathy and neuropathy显示文摘 | Latronieo N Peli E Botteri M | 2005 | Curt Opin Crit Care2005，11，2： | 1 |
| 9 | Prognostic value of Ki - 67 labeling index in patients with node - negative, triple- negative breast cancer显示文摘 | Munzone E Botteri E Sciandivasci A | 2012 | Breast Cancer Res Treat2012，134，1： | 1 |
| 10 | Critical illness myopathy and neuropathy显示文摘 | Latronico N Peli E Botteri M | 2005 | Current Opinion In Critical Care2005，11，： | 1 |
| 11 | Breast phyllodes tumor:a review of literature and a single center retrospective series analysis显示文摘 | Spitaleri G Toesca A Botteri E | | 0，，2： | 1 |
| 12 | Long-term endothelial changes after implantation of anterior chamber intraocular lenses in cataract surgery显示文摘 | Ravalico G Botteri E Baccara F | | 0，，10： | 1 |
| 13 | Cerebral blood flow threshold of ischemic penumbra and infarct core in acute ischemic stroke:a systematic review显示文摘 | BANDERA E BOTTERI M MINELLI C | 2006 | Stroke2006，37，5： | 1 |
| 14 | Cerebral blood flow thresholds for cerebral ischemia in traumatic brain injury:a systematic review显示文摘 | Botteri M Bandera E Minelli C | 2008 | Crit Care Med2008，36，11： | 1 |
| 15 | Critical illness myopathy and neuropathy显示文摘 | Latronico N Peli E Botteri M | 2005 | Curr Opin Crit Care2005，11，2： | 1 |
| 16 | Conservative surgery inpatients with multifocal/ multicen trie breast cancer 显示文摘 | Gentilini 0 Botteri E Rotmensz N | 2009 | BreastCancer Res Treat2009，113，： | 1 |
| 17 | Impact on survival of the number of lymph nodes removed in patients with node-negative gastric cancer submitted to extended lymph node dissection显示文摘 | Biffi R Botteri E Cenciarelli S | | 0，，04： | 1 |
| 18 | Reports from the front line English headteachers' work in an era of practice centralization Management Administration & 显示文摘 | Bottery M | 2007 | Educational Leadership2007，35，1： | 1 |
| 19 | Cerebral blood flow threshold of ischemic penumbra and infarct core in acute ischemic stroke : a sys- tematic review显示文摘 | Bandera E Botteri M Minelli C | 2006 | Stroke2006，37，5： | 1 |
| 20 | Critical illness myopathy and neuropathy 显示文摘 | Latronico N Peli E Botteri M | 2005 | Curr Opin Crit Care2005，11，2： | 1 |
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