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| 1 | Experiments on thermo-hydro-mechanical behaviour of Opalinus Clay at Mont Terri rock laboratory, Switzerland显示文摘Repositories for deep geological disposal of radioactive waste rely on multi-barrier systems to isolate waste from the biosphere.A multi-barrier system typically comprises the natural geological barrier provided by the repository host rock e in our case the Opalinus Clay e and an engineered barrier system(EBS).The Swiss repository concept for spent fuel and vitrified high-level waste(HLW)consists of waste canisters,which are emplaced horizontally in the middle of an emplacement gallery and are separated from the gallery wall by granular backfill material(GBM).We describe here a selection of five in-situ experiments where characteristic hydro-mechanical(HM)and thermo-hydro-mechanical(THM)processes have been observed.The first example is a coupled HM and mine-by test where the evolution of the excavation damaged zone(EDZ)was monitored around a gallery in the Opalinus Clay(ED-B experiment).Measurements of pore-water pressures and convergences due to stress redistribution during excavation highlighted the HM behaviour.The same measurements were subsequently carried out in a heater test(HE-D)where we were able to characterise the Opalinus Clay in terms of its THM behaviour.These yielded detailed data to better understand the THM behaviours of the granular backfill and the natural host rock.For a presentation of the Swiss concept for HLW storage,we designed three demonstration experiments that were subsequently implemented in the Mont Terri rock laboratory:(1)the engineered barrier(EB)experiment,(2)the in-situ heater test on key-THM processes and parameters(HE-E)experiment,and(3)the full-scale emplacement(FE)experiment.The first demonstration experiment has been dismantled,but the last two ones are on-going. | Paul Bossart David Jaeggi Christophe Nussbaum | 2017 | Journal of Rock Mechanics and Geotechnical Engineering2017，9，3： | 3 |
| 2 | Phase I clinical trial with HIV-1gp160 plasmid vaccine in HIV-1-infected asymptomatic subjects显示文摘 | Bossart W Cone R | 2001 | Eur J Clin Microbiol Infect Dis2001，20，11： | 1 |
| 3 | Rapid detection of Mycoplasma pneumoniae in clinical samples by real-time PCR显示文摘 | Hardegger D Nadal D Bossart W | 2000 | J Microbiol Methods2000，41，1： | 1 |
| 4 | Extraction of heavy metals from soils using biodegradable chelating agents显示文摘 | Tandy S Bossart K Mueller R | 2004 | Environ Sci Technol2004，38，3： | 1 |
| 5 | Rapid detection of Mycoplasma pneumoniae in clinical samples by real-time PCR显示文摘 | Hardegger D Nadal D Bossart W | 2000 | J Microbiol Methods2000，41，1： | 1 |
| 6 | The role of CD80 and CD86 in enhancing CD8+cell suppression of HIV replication显示文摘 | Bossart K N Fujimura S H | 1999 | Cell Immunol1999，196，： | 1 |
| 7 | The role of CD80 and CD86 in enhancing CD8^+ cell suppression of HIV replication显示文摘 | BARKER E BOSSART K N FUJIMURA S H | 1999 | Cell Immunol1999，196，： | 1 |
| 8 | Extraction of heavy metals from soils using biodegradable chelating agents 显示文摘 | Tandy S Bossart K Mueller R | 2004 | Environ Sci Teehnol2004，38，3： | 1 |
| 9 | Commuuity-aequired pneumonia in children due to Mycoplasma pneumoniae:diagnostic performance of a seminested 16S rDNA-PCR显示文摘 | NADAL D BOSSART W ZUCOL F | 2001 | Diagn Microbiol Infect Dis2001，39，： | 1 |
| 10 | Rare primary sarcomas of the heart显示文摘 | Milam J D Bossart M I | 1986 | Arch Pathol Lab Med1986，110，12： | 1 |
| 11 | Potent neutralization of Hendra and Nipah viruses by human monoclonal antibodies显示文摘 | Zhu Z Dimitrov AS Bossart KN | 2006 | J Virology2006，80，2： | 1 |
| 12 | Improved impression cytology techniques for the immunopathological diagnosis of super-ficial viral infections显示文摘 | Thiel MA Bossart W Bernauer W | 1997 | Br J Ophthalmol1997，81，： | 1 |
| 13 | The Mont Terri Rock Laboratory,a new international research project in a Mesozoic shale formation in Switzerland显示文摘 | THURY M BOSSART P | 1999 | Engineering Geology1999，52，34： | 1 |
| 14 | Genetic estimates ot popula- tion structure and geneflow: limitations, lessons and new direc- tions 显示文摘 | Bossart J L Prowell D P | 1998 | Trends in Ecology & Evolution1998，13，： | 1 |
| 15 | Potent neutralizaantibodies显示文摘 | Dimitrov AS Bossart KN | 2006 | J Virol2006，80，2： | 1 |
| 16 | Structural and hydro-geological characterisation of the excavation-disturbed zone in the Opalinus Clay(Mont terri Project,Switzerland)显示文摘 | BOSSART P TRICKB T PETER M M | 2004 | Applied Clay Science2004，26，： | 1 |
| 17 | Genetic Architecture of Host Use in a Widely Distributed, Polyphagous Buttesqy (Lepidoptera: Papilionidae ): Adaptive Inferences Based on Comparison of Spatio Temporal Populations 显示文摘 | BOSSART J L | 1998 | Biological Journal of the Linnean Society1998，65，3： | 1 |
| 18 | Membrane fusion tropism and heterotypic functional activities of the Nipah virus and Hendra virus envelope glycoproteins 显示文摘 | Bossart K N Wang Lin-Fa Flora M N | 2002 | J Virol2002，76，11： | 1 |
| 19 | Polybrominated Diphenyl Ethers (PBDEs) in Blubber of Free-Ranging Bottlenose Dolphins (Tursiops Truncatus) from Two Southeast Atlantic Estuarine Areas显示文摘 | Patricia A. Fair Gregory Mitchum Thomas C. Hulsey Jeff Adams Eric Zolman Wayne McFee Ed Wirth Gregory D. Bossart | 2007 | Archives of Environmental Contamination and Toxicology2007，，3： | 1 |
| 20 | The potential impact of biomarker-guided triage decisions for patients with urinary tract infections显示文摘 | A. Litke R. Bossart K. Regez U. Schild M. Guglielmetti A. Conca P. Sch?fer B. Reutlinger B. Mueller W. C. Albrich | 2013 | Infection2013，，： | 1 |
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