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62篇 您的检索式：作者名="Bonaz"

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	题名	作者	年代	出处	被引量
1	Brain-gut-microbiota axis in Parkinson's disease显示文摘Parkinson's disease(PD) is characterized by alphasynucleinopathy that affects all levels of the braingut axis including the central, autonomic, and enteric nervous systems. Recently, it has been recognized that the brain-gut axis interactions are significantly modulated by the gut microbiota via immunological,neuroendocrine, and direct neural mechanisms. Dysregulation of the brain-gut-microbiota axis in PD may be associated with gastrointestinal manifestations frequently preceding motor symptoms, as well as with the pathogenesis of PD itself, supporting the hypothesis that the pathological process is spread from the gut to the brain. Excessive stimulation of the innate immune system resulting from gut dysbiosis and/or small intestinal bacterial overgrowth and increased intestinal permeability may induce systemic inflammation, while activation of enteric neurons and enteric glial cells may contribute to the initiation of alpha-synuclein misfolding.Additionally, the adaptive immune system may be disturbed by bacterial proteins cross-reacting with human antigens. A better understanding of the brain-gutmicrobiota axis interactions should bring a new insight in the pathophysiology of PD and permit an earlier diagnosis with a focus on peripheral biomarkers within the enteric nervous system. Novel therapeutic options aimed at modifying the gut microbiota composition and enhancing the intestinal epithelial barrier integrity in PD patients could influence the initial step of the following cascade of neurodegeneration in PD.	Agata Mulak Bruno Bonaz	2015	World Journal of Gastroenterology2015，21，37：	60
2	Corticotropin-releasing factor receptors and stress-related alterations of gut motor function 显示文摘	Tach6 Y Bonaz B	2007	J Clin Invest2007，117，：	1
3	Irritable bowel syndrome:a model of thebrain-gut interactions显示文摘	Mulak A T Bonaz B	2004	Med Sci Monit2004，10，4：	1
4	Corticotropin - releasing factor receptors and stress - related alterations of gut motor function 显示文摘	Tache Y Bonaz B	2007	J Clin Invest2007，117，1：	1
5	Technical and functional results after laparoscopic rectopexy to the promontory for complete rectal prolapse显示文摘	Thomas Auguste Alain Dubreuil Richard Bost Bruno Bonaz Jean-Luc Faucheron	2006	Gastroenterologie Clinique et Biologique2006，，5：	1
6	Central processing of rectal pain in patients with irritable bowel syndrome:an fMRI study显示文摘	Bonaz B Baciu M Papillon E	2002	Am J Gastroenterol2002，97，3：	1
7	Brain-gut interactions in inflammatory bowel disease 显示文摘	Bonaz BL Bernstein CN	2013	Gastroenterology2013，144，1：	1
8	Primary biliary cirrhosis显示文摘	Roblin X Bonaz B	2005	N Engl J Med2005，353，：	1
9	Acute exacerbation of pain in irritable bowel syndrome:efficacy of phloroglucinol/ trimethylphlorog lucinol 显示文摘	CHASSANY O BONAZ B BRULEY S	2007	Aliment Phannacol Ther2007，25，9：	1
10	The cholinergic anti-inflammatory pathway and the gastrointestinal tract显示文摘	Bonaz B	2007	Gastroenterology2007，133，4：	1
11	Effect of a chronic stress on CRF neuronal activity and expression of its type 1 receptor in the rat brain显示文摘	Rivest S	1998	Am J Physiol1998，275，52：	1
12	Irritable bowel syndrome:a model of the brain-gut interactions显示文摘	Mulak A Bonaz B	2004	Med Sci Monit2004，10，4：	1
13	Effect of a chronic stress on CRF neuronal activity and expression of its type 1 receptor in the rat brain显示文摘	Rivest S	1998	AM J Physiology1998，，52：	1
14	Central processing of rectal pain in IBS patients:an MRI study显示文摘	Bonaz B L Papillon E Baciu M	2000	Gastroenterology2000，，：	1
15	Peripheral bombesin induces c-fos protein in the brain显示文摘	Bonaz B deGiorgio Tache Y	1993	Brain Res1993，600，：	1
16	Neuronal pathways involved in abdominal surgery-induced gastric ileus in rats显示文摘	Barquist E Bonaz B Martinez V	1996	Am J Physiol1996，270，：	1
17	Corticotropin-releasing factor and systemic capsaicin-sensitive afferents are involved in abdominal surgery-induced Fos expression in the paraventricular nucleus of the hypothalamus 显示文摘	Bonaz B Tache Y	1997	Brain Res1997，748，12：	1
18	Cen- tral processing of metal pain in patients with irritable bowel syndrome: an fMRI study 显示文摘	Bonaz B Baciu M Papillon E	2002	Am J Gastroenterology2002，97，3：	1
19	Corticotropin - releasing factor receptors and stress - related alterations of gut motor function 显示文摘	Tach6 Y Bonaz B	2007	J Clin Invest2007，117，1：	1
20	Vagus nerve stimulation : from epilepsy to the cholinergic anti-inflammatory pathway 显示文摘	Bonaz B Picq C Sinniger V	2013	Neurogastroenterol Moti12013，25，3：	1

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