|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hypolipidemic and anti-atherosclerogenic effects of aqueous extract of Ipomoea batatas leaves in diet-induced hypercholesterolemic rats显示文摘Objective:Ipomoea batatas(L.)Lam.is a food plant used in African traditional medicine to treat cardiovascular diseases and related conditions.We assessed the hypolipidemic and anti-atherosclerogenic properties of the aqueous extract of I.batatas leaves in a rat model of diet-induced hypercholesterolemia.Methods:Hypercholesterolemia was induced in male Wistar rats by exclusive feeding with a cholesterolenriched(1%)standard diet for four weeks.Then,rats were treated once daily(per os)with I.batatas extract at doses of 400,500 and 600 mg/kg or with atorvastatin(2 mg/kg),for four weeks.Following treatment,animals were observed for another four weeks and then sacrificed.Aortas were excised and processed for histopathological studies,and blood glucose level and lipid profile were measured.Results:Hypercholesterolemic animals experienced a 21.5%faster increase in body weight,significant increases in blood glucose and blood lipids(148.94%triglycerides,196.97%high-density lipoprotein cholesterol,773.04%low-density lipoprotein cholesterol,148.93%very low-density lipoprotein cholesterol and 210.42%total cholesterol),and increases in aorta thickness and atherosclerotic plaque sizes compared to rats fed standard diet.Treatment of hypercholesterolemic rats with the extract mitigated these alterations and restored blood glucose and blood lipid levels to normocholesterolemic values.Conclusion:Our findings suggest that I.batatas leaves have hypolipidemic and anti-atherosclerogenic properties and justify their use in traditional medicine. | Fidele Ntchapda Fernand C.Tchatchouang David Miaffo Barthelemy Maidadi Lorella Vecchio Rodrigue E.Talla Christian Bonabe Paul F.Seke Etet Theophile Dimo | 2021 | Journal of Integrative Medicine2021，19，3： | 2 |
| 2 | Phase 1 trial of autologous bone marrow mesenchymal stem cell transplantation in patients with decompensated liver cirrhosis显示文摘 | Mohamadnejad M Alimoghaddam K Mohyeddin- Bonab M | 2007 | Arch Iranian Med2007，10，4： | 1 |
| 3 | Effects of depositional and diagenetic characteristics on carbonate reservoir quality: A case study from the South Pars gas field in the Persian Gulf显示文摘 | Dizaji B E Bonab H R | 2009 | Petroleum Geoscience2009，15，： | 1 |
| 4 | Aging of mesenchymal stem cellin vitro显示文摘 | Bonab MM Alimoghaddam K Talebian F | | 0，，： | 1 |
| 5 | Aging of mesenehymal stem cell in vitro 显示文摘 | BONAB MM ALIMOGHADDAM K TALEBIAN F | 2006 | BMC Cell Biol2006，7，： | 1 |
| 6 | Aging of mesenchymal stem cell in vitro 显示文摘 | Bonab M M Alimoghaddam K Talebian F | 2006 | BMC Cell Biol2006，7，： | 1 |
| 7 | Aging of mesenchymal stem celt in vitro显示文摘 | BONAB M M ALIMOGHADDAM K TALEBIAN F | 2006 | BMC Cell Biol2006，7，： | 1 |
| 8 | Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo 显示文摘 | Carter EA Bonab AA Hamrahi V | 2011 | Life Sci2011，89，34： | 1 |
| 9 | Aging of mesenchymal stem cell in vitro显示文摘 | BONAB M M ALIMOGHADDAM K TALEBIAN F | 2006 | Bio Med Central Cell Biology2006，7，14： | 1 |
| 10 | Aging of mesenchymal stem cell in vitro显示文摘 | Bonab MM Alimoghaddam K Talebian F | 2006 | BMC Cell Biol2006，7，3： | 1 |
| 11 | Does mesenchymal stem cell therapy help multiple sclerosis patients? Report of a pilot study显示文摘 | Mohyeddin Bonab M Yazdanbakhsh S Lotfi J | | 0，，01： | 1 |
| 12 | Aging of mesenchymal stem cell in vitro 显示文摘 | Mandana Mohyeddin Bonab Kamran alimoghaddam Fatemeh Talebian | 2006 | BMC Cell Biol2006，7，： | 1 |
| 13 | Which factors can affect cord blood variables显示文摘 | Oyeddin Bonab MA Alimoghaddam KA Goliaei ZA | 2004 | Transfusion2004，44，50： | 1 |
| 14 | Globalization and the Role of E-commerce in Its Expansion显示文摘 | Ali Ghorbani Mohammah Bakhtazmay Bonab | 2013 | Journal of Basic and Apply Scientific Research2013，3，： | 1 |
| 15 | Association of heat production with 1 8F-FDGaccumulation in murine brown adipose tissueafter stress显示文摘 | CARTER E A BONAB A A PAUL K | | J Nuc! Med0，52，10： | 1 |
| 16 | Aging of mes- enchymal stem cell in vitro显示文摘 | Bonab MM Alimoghaddam K Talebian F | 2006 | BMC Cell Biol2006，7，： | 1 |
| 17 | Which factors can affect cord blood variables显示文摘 | MOHYEDDIN BONAB MA ALIMOGHADDAM KA | 2004 | Transfusion2004，44，5： | 1 |
| 18 | Aging of mesenchymal stem cell in vitro显示文摘 | Bonab MM Alimoghaddam K Talebian F | 2006 | BMC Cell Biol2006，7，： | 1 |
| 19 | Impact of pregnancy on the outcome of kidney transplantation 显示文摘 | Kashanizadeh N Nemati E Sharifi- Bonab M | 2007 | Transplant Proc2007，39，4： | 1 |
| 20 | Effects of depositional and diagenetic characteristics on carbonate reservoir quality: A case study from the South Pars gas field in the Persian Gulf显示文摘 | Dizaji B E Bonab H R | 2009 | Petroleum Geoscience2009，15，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员