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	题名	作者	年代	出处	被引量
1	Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.	Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel	2014	World Journal of Gastroenterology2014，20，42：	5
2	“两弹一星”工程的成功经验与启示显示文摘'两弹一星'工程是国家的重大科技工程,在中国20世纪所取得的重大科技成就中名列第一。在实施'两弹一星'工程中形成了一整套符合中国国情且行之有效的领导、组织和管理模式,主要有:实施科学决策和集中统一的组织领导、制定科学的战略规划、确立正确的指导方针、采取独具特色的组织管理机制和在工程实践中建设科研生产队伍等五个方面。梳理总结这些成功经验,对新时期国家重大科技专项的领导、组织、管理等具有特殊意义。	Atomic and Hydrogen Bomb and Artificial Satellite Historical Research Branch of National History Association of the People’s Republic of China	2013	当代中国史研究2013，20，5：	2
3	Effect of rofecoxib on platelet aggregation and blood loss in gynaecological and breast surgery compared with diclofenac 显示文摘	Hegi T Bombeli T Seifert B	2004	Br J Anaesth2004，92，3：	1
4	Endothelial cells undergoing apoptosis become proadhesive for nonactivated platelets显示文摘	Bombeli T Schwartz BR Harlan JM	1999	Blood1999，93，11：	1
5	Apoptosis vascular endothelial cells become procoagulant显示文摘	Bombeli T Karsan A	1997	Blood1997，89，：	1
6	Endocarditis due to Chryseobac-terium meningosepticum显示文摘	Bomb K Arora A Trehan N		0，，02：	1
7	Apoptotic vascular endothelial cells become procoagulant显示文摘	Bombeli T Karsan A Tait JF	1997	Blood1997，89，7：	1
8	Citrate storage affects Thrombelastograph analysis 显示文摘	Camenzind V Bombeli T Seifert B	2000	Anesthesiology2000，92，：	1
9	Apoptotic vascular endotheli- al cells become procoagulant 显示文摘	Bombeli T Karsan A Tait JF	1997	Blood1997，89，7：	1
10	Apoptotic vascular endothelial cells become procoagulant 显示文摘	Bombeli T Karsan A Tait JF Harlan JM	1997	Blood1997，89，7：	1
11	Vacuum seal- ing as treatment of soft tissue damage in open fractures 显示文摘	Fleischmann W Strecker W Bombeli M	1993	Unfallchirurg1993，96，9：	1
12	Role of the spacer of cationic Gemini amphiphiles in the condensation of DNA 显示文摘	Bombeli C Borocci S Diociaiuti M	2005	Langmuir2005，21，10：	1
13	Role of the spacer of cationic gemini amphiphiles in the condensation of DNA 显示文摘	Bombeli C Borocci S Diociaiuti M	2005	Langmuir2005，21，10：	1
14	Adhesion of activated platelets to endothelial cells :evidence for a GP Ⅱb/Ⅲa-dependent bridging mechanism and novel roles for endothelial intercellular adhesion molecule 1 ( ICAM-1 ), alphavbeta 3 integrin,and GP I balpha 显示文摘	Bombeli T Schwartz BR Harlan JM	1998	J Exp Med1998，187，3：	1
15	Low and medium-molecular weight hydroxyethyl starches :comparison of their effect on blood coagulation 显示文摘	Jamnicki M Bombeli T Seifert B	2000	Anesthesiology2000，93，5：	1
16	Low- and hydroxyethyl starches: on blood coagulation 显示文摘	JAMNICKI M BOMBELI T medium-molecular-weight comparison of their effect Anesthesiology 2000 93(5) SEIFERT B	2000	1231-12372000，，：	1
17	Endothelial ceils undergoing apoptosis become proadhesive for nonactivated platelets显示文摘	Bombeli T Schwartz BR Hadan JM	1999	Blood JT1999，93，11：	1
18	Vacuum sealing as treatment of soft tissue damage in open fraetures 显示文摘	Fleisehmann W Streeker W Bombeli M	1993	Unfall- chirurg1993，96，9：	1
19	Endothelial cells undergoing apoptosis become proadhesive for nonactivated platelets显示文摘	Bombeli T Schwartz BR Harlan JM	1999	Blood1999，93，：	1
20	Updates in perioperative coagulation: physiology and management of thromboembolism and haemorrhage 显示文摘	Bombeli T Spahn DR	2004	Br J Anaesth2004，93，2：	1

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