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| 1 | Synchronous occurrence of gastrointestinal stromal tumors and other primary gastrointestinal neoplasms显示文摘AIM: To review clinical and pathologic features of Gas-trointestinal stromal tumors (GISTs) occurring synchro-nously with other primary gastrointestinal neoplasms.METHODS: Twenty-eight patients with primary GIST were treated at our institution between 1989 and 2005. Clinical and pathologic records were reviewed. RESULTS: The gastrointestinal stromal tumor occurred simultaneously with other primary GI malignancies in 14% of all patients with GIST. The synchronous stromal tumors were located in the stomach and were incidentally found during the operation. The coexistent neoplasms were colon adenocarcinoma, gastric cancer (2 cases) and gastric lymphoma.CONCLUSION: The synchronous occurrence of GISTs and other gastrointestinal malignancies is more common than it has been considered. The development of gastrointestinal stromal tumors and other neoplasms may involve the same carcinogenic agents. | Marek Wronski Bogna Ziarkiewicz-Wroblewska Barbara Gornicka Wlodzimierz Cebulski Maciej Slodkowski Aleksander Wasiutynski Ireneusz W Krasnodebski | 2006 | World Journal of Gastroenterology2006，12，33： | 14 |
| 2 | High on food: the interaction between the neural circuits for feeding and for reward显示文摘饥饿,主要在精力由缺乏开始了,导致寻求的食物和吸入。然而,向食物的开车是不仅由生理的需要调整了,而且被从食物的摄取导出的快乐激发,特别地好吃的食物。因此,喂被看作包含在喂电路和报酬电路的 homeostatic 之间的综合通讯的适应激发的行为。一个喂的事件的开始和结束被许多 neuronal 信号,和不适应的粘性在几乎任何东西指示网络的部件可以导致病理学的吃的混乱的开发。在这评论,我们将总结在大脑的喂的电路和报酬电路怎么交往的最近的理解。我们将强调在视下丘和 mesolimbic 多巴胺系统之间的通讯并且为这块地加亮复杂性,差异,待研究的问题和未来方向。 | Jing-Jing Liu Diptendu Mukherjee Doron Haritan Bogna Ignatowska-Jankowska Ji Liu Ami Citri Zhiping P. Pang | 2015 | Frontiers in Biology2015，10，2： | 3 |
| 3 | Gastroenterology service in a teaching hospital in rural New Zealand, 1991-2003显示文摘AIM: To retrospectively collect inpatient and outpatient data and to assess the use of endoscopic procedures during the years 1991, 1997 and 2003 to analyse for trends. METHODS: This retrospective survey was conducted in a University-associated Gastroenterology Unit offering secondary and tertiary health care services for a population of approximately 182 000 people in Southern New Zealand. Data collected included patient contacts (inand outpatients), gastroscopic and colonoscopic investigations. RESULTS: We observed a significant increase in the absolute numbers of patient contacts over the years (1991: 2308 vs 1997: 2022 vs 2003: 2783, P < 0.0001) with inflammatory bowel disease, other diseases of the colon, anus and rectum and iron studies related disorders decreasing significantly but liver disease and constipation increasing linearly over time. The use of endoscopy services remained relatively stable but colonoscopic investigations for a positive family history of colorectal cancer increased significantly while more gastroscopies were performed for unexplained anaemia. CONCLUSION: The whole spectrum of gastroenterology contacts was studied. A substantial proportion of colonoscopies and outpatient consultations were undertaken to screen for colorectal cancer. This proportion is likely to grow further. Our fi ndings have implications for the recruitment and training of the next generation of gastroenterologists. | Michael Schultz Andrew Davidson Sarah Donald Bogna Targonska Angus Turnbull Susan Weggery Vicki Livingstone John D Dockerty | 2009 | World Journal of Gastroenterology2009，15，5： | 3 |
| 4 | The evaluation of IL-12 concentration, PAF-AH, and PLA 2 activity in patients with type 1 diabetes treated with intensive insulin therapy显示文摘 | Ma?gorzata Wegner Aleksandra Araszkiewicz Anna Pioruńska-Miko?ajczak Dorota Zozulińska-Zió?kiewicz Bogna Wierusz-Wysocka Maria Pioruńska-Stolzmann | 2009 | Clinical Biochemistry2009，，16： | 1 |
| 5 | Effect of zirconia surface treatments on the shear strength of zirconia A, eneering ceramic composites 显示文摘 | Jens F Philipp G Bogna S | 2008 | Dent Mater J2008，27，3： | 1 |
| 6 | Prevalence of IFNL3 rs4803217 single nucleotide polymorphism and clinical course of chronic hepatitis C显示文摘AIM To evaluate the association of IFNL3(IL28B) SNP rs4803217 with severity of disease and treatment outcome in chronic hepatitis C(CHC).METHODS The study enrolled 196 CHC Polish patients(82 women and 114 men in age 20-64) infected with hepatitis C virus(HCV) genotype 1. They were treatment na?ve and qualified to pegylated interferon alpha(PEG-IFN-α) and ribavirin(RBV) therapy. The analyzed baseline parameters included: degree of inflammation, stage of fibrosis, viral load as well as alanine aminotransferase(ALT), asparagine aminotransferase(AST) and total bilirubin(TBIL). The analysis of response to therapy included: sustained virological response(SVR), defined as undetectable serum HCV RNA level six month after completion of 48-wk therapy, and relapse, defined as achieving undetectable viral load at the end of treatment but not SVR. HCV genotyping and HCV RNA quantification were performed using commercially available tests. DNA was isolated from peripheral blood mononuclear cells or from buccal cell swabs. In addition to rs4803217, also single nucleotide polymorphisms(SNPs)(rs12979860, rs8099917 and rs12980275) of known significance in predicting of HCV clearance were analyzed. SNPs were determined by high resolution melt analysis and confirmed by sequencing of amplicons. RESULTS Frequency of rs4803217 genotypes in studied group was as follows: 27.55%; 54.59% and 17.86% for CC, CA and AA, respectively. The rs4803217 SNP, similar to other analyzed SNPs, was not associated with severity of CHC(grade of inflammation, stage of fibrosis, baseline viral load as well as biochemical parameters: ALT, AST, TBIL). It was demonstrated that the rs4803217 C allele is associated with SVR(C vs A: P < 0.0001; dose of C allele: P = 0.0002) and nonrelapse(C vs A: P = 0.001; dose of C allele: P = 0.002). Moreover, it was found that patients with CC genotype have significantly higher response rates as compared with CA/AA patients(P < 0.0001), whereas patients carrying A allele are significantly predisposed to relapse after treatment(P = 0.0007). Moreover, the association of rs4803217 with SVR was comparable to that of rs12979860 and stronger as observed for rs12980275 and rs8099917. Association of rs4803217 with relapse, was the strongest as compared with the other SNPs. The analysis of combined rs4803217 and rs8099917 genotypes demonstrated that additional genotyping of rs8099917 had no significant impact on the prediction of SVR. Multivariate analysis revealed that among analyzed SNPs only rs4803217 is an independent predictor of SVR(P = 0.016) and relapse(P = 0.024). CONCLUSION The rs4803217 SNP is a strong, independent and superior predictor of SVR and relapse in HCV genotype 1 infected CHC patients treated with PEG-IFN-α and RBV. | Bogna Swiatek-Koscielna Ewelina Kaluzna Ewa Strauss Jerzy Nowak Iwona Bereszyńska Ewelina Gowin Jacek Wysocki Jolanta Rembowska Dominika Barcińska Iwona Mozer-Lisewska Danuta Januszkiewicz-Lewandowska | 2017 | World Journal of Gastroenterology2017，23，21： | 1 |
| 7 | Challenging the “Grago” double float process Ⅱ aminefatty acid flotation of siliceoue phosphate显示文摘 | Zhang P Yu Y Bogna M | 1997 | Minerals Engineering1997，10，9： | 1 |
| 8 | The diagnostic value of matrix metalloproteinase 9(MMP-9)and tissue inhibitor of matrix metalloproteinases 1(TIMP-1)determination in the sera of colorectal adenoma and cancer patients显示文摘 | Barbara M Magdalena G Bogna O | 2010 | Int J Colorectal Dis2010，25，10： | 1 |
| 9 | cBN - TiN, cBN - TiC composites: chemical equilibria, mi- crostructure and hardness mechanical investigations显示文摘 | Benko Ewa Stanislaw Jan Skrzypek licka Bogna Kro | 1999 | Dia- mond and Related Materials1999，8，： | 1 |
| 10 | Is interleukin-10 gene polymorphism a predictive marker in HCV infection?显示文摘 | Bogna J. ?wi?tek | 2012 | Cytokine and Growth Factor Reviews (-)2012，，1： | 1 |
| 11 | Load-bearing capacity and failuretypes of anterior zireonia Cr Owl FIS veneerled with overpressing and layering teehniques显示文摘 | Bogna S Mutlu O Malgorzata R | 2011 | Dental Materials2011，27，10： | 1 |
| 12 | Fracture load and failure analysis of zirconia sigle crowns veneered with pressed and layered ceramics after Chewing simulation 显示文摘 | Bogna S Mutlu O Malgorzata R | 2011 | Dental Materials Journal2011，30，4： | 1 |
| 13 | Mesenteric fibromatosis with intestinal involvement mimicking a gastrointestinal stromal tumour 显示文摘 | Marek W Bogna Z W Maciej S | 2011 | Radial Oncol2011，45，1： | 1 |
| 14 | Load-bearing capacity and fail- ure xirconia cro types of anterior wns veneered with overpressing and layering techniques 显示文摘 | Bogna S Mutlu O Malgorzata R | 2011 | Dental Materials2011，27，10： | 1 |
| 15 | Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications a review显示文摘 | Bogna G G | 2014 | Nutrition2014，13，： | 1 |
| 16 | Load-bearing capacity and failure types of anterior zirconia crowns veneered with overpressing and layering techniques 显示文摘 | Bogna S Mutlu O Malgorzata R | 2011 | Dental Materials2011，27，10： | 1 |
| 17 | Repair of silorane com- posite : using the same substrate or a methacrylate-based composite 显示文摘 | Annette W Bogna S Wolfgang B | 2012 | Dent Mater2012，28，3： | 1 |
| 18 | Effect of Zirconia Surface Treatments on the Shera of Zirconia/Veneering Ceramic Composites显示文摘 | Jens F Philipp G Bogna S | 2008 | Dental Materials Journal2008，279，3： | 1 |
| 19 | Arrhythmogenic right ventricular cardiomyopathy in two pairs of monozygotic twins显示文摘 | Elzbiet K. Wlodarska Marek Konka Teresa Zaleska Rafal Ploski Krzysztof Cedro Bogna Pucilowska Monika Bekiesinska-Figatowska Wanda Rydlewska-Sadowska Witold Ruzyllo Piotr Hoffman | 2005 | International Journal of Cardiology2005，，2： | 1 |
| 20 | Peroxisome proliferator-activated recep- tors and their ligands: nutritional and clinical implications a review显示文摘 | Bogna Grygiel-G6rniak | 2014 | Nutr J2014，13，： | 1 |
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