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| 1 | Endothelial dysfunction as a predictor of cardiovascular disease in type 1 diabetes显示文摘Macro and microvascular disease are the main cause of morbi-mortality in type 1 diabetes(T1DM).Although there is a clear association between endothelial dysfunction and atherosclerosis in type 2 diabetes,a cause-effect relationship is less clear in T1 DM.Although endothelial dysfunction(ED) precedes atherosclerosis,it is not clear weather,in recent onset T1 DM,it may progress to clinical macrovascular disease.Moreover,endothelial dysfunction may either be reversed spontaneously or in response to intensive glycemic control,long-term exercise training and use of statins.Acute,long-term and post-prandial hyperglycemia as well as duration of diabetes and microalbuminuria are all conditions associated with ED in T1 DM.The pathogenesis of endothelial dysfunction is closely related to oxidative-stress.NAD(P)H oxidase over activity induces excessive superoxide production inside the mitochondrial oxidative chain of endothelial cells,thus reducing nitric oxide bioavailability and resulting in peroxynitrite formation,a potent oxidant agent.Moreover,oxidative stress also uncouples endothelial nitric oxide synthase,which becomes dysfunctional,inducing formation of superoxide.Other important mechanisms are the activation of both the polyol and protein kinase C pathways as well as the presence of advanced glycation end-products.Future studies are needed to evaluate the potential clinical applicability of endothelial dysfunction as a marker for early vascular complications in T1 DM. | Marcello C Bertoluci Gislaine V Cé Antonio MV da Silva Marco V Wainstein Winston Boff Marcia Punales | 2015 | World Journal of Diabetes2015，6，5： | 5 |
| 2 | Computer-aided-design/computer-assisted-manufactured adhesive restoration of molars with a compromised cusp:effect of fiber-reinforced immediate dentin sealing and cusp overlap on fatigue strength显示文摘 | Magne P Boff LL Oderich E | 2012 | J Esthet Restor Dent2012，24，2： | 1 |
| 3 | Structural and magnetic properties of Fe-Al2O3 films显示文摘 | TEIXEIRAA S R BOFF M A S FLORES W H | 2001 | J Magn Magn Mater2001，233，1： | 1 |
| 4 | Physieoehemieal properties of cassava starch oxidized by sodium hypoehlorite显示文摘 | GARRIDO L SCHNITZLER E de BOFF S | 2014 | Journal of Food Science and Technology2014，51，10： | 1 |
| 5 | Important aspects regarding the role of microorganisms in bisphosphonate-related osteonecrosis of the jaws显示文摘 | Boff RC Salum FG Figueiredo MA | 2014 | Arch Oral Biol2014，59，8： | 1 |
| 6 | Clinician’s guide to prevention and treatment of osteoporosis显示文摘 | Cosman F De Beur S J Le Boff M S | 2014 | Osteoporosis international2014，25，10： | 1 |
| 7 | Reaching Out to the Underserved: More Than Thirty Years of Outreach Job Ads显示文摘 | Colleen Boff Carol Singer Beverly Stearns | 2005 | The Journal of Academic Librarianship2005，，2： | 1 |
| 8 | A 2-screw fixation technique for subtalarjoint fusion: a retrospective case series introducing a novel 2-screwfixation construct with operative pearls显示文摘 | Boffeli TJ Reinking RR | 2012 | J Foot Ankle Surg2012，51，6： | 1 |
| 9 | Reaching out to the underserved: More than thirty years of outreach job ads 显示文摘 | Boff C Singer C | 2006 | The Journal of Academic Librarianship2006，32，2： | 1 |
| 10 | R&D/technology management:A framework for putting technology to work显示文摘 | Rouse W B Boff K R | 1998 | IEEE Transactions on Systems Man and Cybernetics1998，28，4： | 1 |
| 11 | Structural and magnetic properties of Fe-Al2O3 films显示文摘 | Teixeira S R Boff M A S Flores W H | 2001 | J Magn Magn Mater2001，233，： | 1 |
| 12 | Effect of thermal processing and carbon dioxide-assisted high-pressure processing on pectinmethylesterase and chemical changes in orange juice 显示文摘 | Boff J M Truong T T Min D B | 2003 | Journal of Food Science2003，68，4： | 1 |
| 13 | Important aspects regarding the role of microorganisms in bisphosphonate-related osteonecrosis of the jaws显示文摘 | Boff RC Salum FG Figueiredo MA | 2014 | Arch Oral Biol2014，59，8： | 1 |
| 14 | Modified Dwyer osteotomy with rotation and reinsertion of autograft bone wedge for residual heel deformity de- spite previous delayed subtalar joint arthrodesis after calcaneal fracture 显示文摘 | BOFFELI TJ ABBEN KW | 2014 | J Foot Ankle Surg2014，53，6： | 1 |
| 15 | Identification of up-regulated genes in flag leaves during rice grain filling and characterization of OsNAC5,a new ABA-dependent transcription factor显示文摘 | Sperotto RA Ricachenevsky FK Duarte GL Boff T Lopes KL Sperb ER Grusak MA Fett JP | | 0，，05： | 1 |
| 16 | Reaching Out to the Underserved: More Than Thirty Years of Outreach Job Ads 显示文摘 | Boff C Singer C | 2006 | The Journal of Academic Librarianship2006，，2： | 1 |
| 17 | Nickel complexes based on tridentate pyrazolyl ligands for highly efficient dimerization of ethylene to 1-butene显示文摘 | Ajellal N Kuhn M C A Boff A D G | 2006 | Organometallics2006，25，5： | 1 |
| 18 | Assessing cost/benefits of research and development investments显示文摘 | Rouse W B Boff K R Sutlry Thomas B G | 1997 | IEEE Trans on Systems Man and Cybernetics-Part A1997，27，4： | 1 |
| 19 | Assessing cost benefits of research and development investments 显示文摘 | Rouse W B Boff K R Sutiry Thomas B G | 1997 | IEEE Transactions on Systems Man and Cybernet- ics-Part A: Systems and Humans1997，27，4： | 1 |
| 20 | Effects of carbon dioxide and high pressure processing on pectinmethylesterase in single-strength orange juice显示文摘 | TRUONG T T BOFF J M MIND B | 2002 | Journal of Food Science2002，67，8： | 1 |
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