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151篇 您的检索式:作者名="Boecker"
    题名 作者 年代 出处 被引量
1Fibroadhesive scarring of grafted collagen scaffolds interferes with implant–host neural tissue integration and bridging in experimental spinal cord injury显示文摘Severe traumatic spinal cord injury(SCI)results in a devastating and permanent loss of function,and is currently an incurable condition.It is generally accepted that future intervention strategies will require combinational approaches,including bioengineered scaffolds,to support axon growth across tissue scarring and cystic cavitation.Previously,we demonstrated that implantation of a microporous type-I collagen scaffold into an experimental model of SCI was capable of supporting functional recovery in the absence of extensive implant–host neural tissue integration.Here,we demonstrate the reactive host cellular responses that may be detrimental to neural tissue integration after implantation of collagen scaffolds into unilateral resection injuries of the adult rat spinal cord.Immunohistochemistry demonstrated scattered fibroblast-like cell infiltration throughout the scaffolds as well as the presence of variable layers of densely packed cells,the fine processes of which extended along the graft–host interface.Few reactive astroglial or regenerating axonal profiles could be seen traversing this layer.Such encapsulation-type behaviour around bioengineered scaffolds impedes the integration of host neural tissues and reduces the intended bridging role of the implant.Characterization of the cellular and molecular mechanisms underpinning this behaviour will be pivotal in the future design of collagen-based bridging scaffolds intended for regenerative medicine.Haktan Altinova Sebastian Hammes Moniek Palm Jose Gerardo-Nava Pascal Achenbach Ronald Deumens Emmanuel Hermans Tobias Fuhrmann Arne Boecker Sabien Geraldine Antonia van Neerven Ahmet Bozkurt Joachim Weis Gary Anthony Brook 2019Regenerative Biomaterials2019,6,2:4
2Mutations inthe gene encoding the synaptic scaffolding protein SHANK3are associated with autism spectrum disorders显示文摘Durand CM Betancur C Boeckers TM 2007Nat Gen-et2007,39,:1
3Differential surface plasmon resonance imaging for high-throughput bioanalyses 显示文摘BOECKER D ZYBIN A HORVATIC V 2007Analytical Chemistry2007,79,:1
4The Flame Retardants Tetrabromobisphenol A-Bisallylether Suppress the Induction of Interleukin-2 Receptor a Chain (CD25) in Murine Splenocytes显示文摘Sabine Pullen Ronald Boecker Gisa Tiegs 2003Toxicology2003,184,:1
5Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ显示文摘Boecker W Moll R Dervan P 2002J Pathol2002,198,4:1
6Sensory processing in Parkinson's and Huntington's disease: Investigations with 3d H(2)(15)O-PET显示文摘Boecker H Ceballos-Baumann A Bartenstein P 1999Brain1999,122,:1
7The flame retardants tetrabromobisphenol A and tetrabromobisphenol A- bisallylether suppress the induction of interleukin-2 receptor alpha chain (CD25) in murine splenocytes 显示文摘Pullen S Boecker R Tiegs G 2003Toxicology2003,184,1:1
8Postsynaptic density assembly is fundamentally different from presynaptic active zone assembly显示文摘BRESLER T SHAPIRA M BOECKERS T 2004J Neurosci2004,24,6:1
9Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders 显示文摘Durand CM Betancur C Boeckers TM 2007Nat Genet2007,39,1:1
10QRS duration:a simple marker for predicting cardiac mortality in ICD patients with heart failure显示文摘Bode-Schnurbus L Boecker D Block M 2003Heart2003,89,10:1
11Silicon carbide:from acheson's invention to new industrial products显示文摘Boecker W D G 1997Cfi/Ber DKG1997,74,5:1
12The flame retardantstetrabromobisphenol A and tetrabromobisphenol A-bisallylether suppress theinduction of interleukin-2 receptor alpha chain(CD25)in murinesplenocytes显示文摘PULLEN S BOECKER R TIEGS G 2003Toxicology2003,184,1:1
13Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages:a new cell biological concept显示文摘Boecker W Moll R Poremba C 2002Lab Invest2002,82,:1
14Usual ductal hyperplasia of the breast is a committed stem(progenitor) cell losion distinct from atypical ductal hyperplasia and ductal carcinoma in situ显示文摘Boecker W Moll R Dervan P 2002J Pathol2002,198,:1
15Pathological work-up of sentinel lymph nodes in breast cancer. Review of current data to be considered for the formulation of guidelines显示文摘G. Cserni I. Amendoeira N. Apostolikas J.P. Bellocq S. Bianchi G. Bussolati W. Boecker B. Borisch C.E. Connolly T. Decker P. Dervan M. Drijkoningen I.O. Ellis C.W. Elston V. Eusebi D. Faverly P. Heikkila R. Holland H. Kerner J. Kulka J. Jacquemier M. Lace 2003European Journal of Cancer2003,,12:1
16Experiences with ultrasound-guidedport implatations via the lateral subclavain vein: a retrospective analysis of 1532 patients 显示文摘Chang DH Boecker J Hellmich M 2012Rofo2012,184,8:1
17Usual ductal hyperplasia of the breast is a commited stem(progenitor) cell lesion distinct from a- typical ductal hyperplasia and ductal carcinoma in situ 显示文摘Boecker W Moll R Dervan P 2002J Pathol2002,198,4:1
18Ductal epithelial proliferations of the breast: a bioiogical continuum? Comparative genomic hybridization and high-molecular-weight cytokeralin expression pat terns 显示文摘Boecker W Buerger H Schmitz K 2001J Pathol2001,195,4:1
19Distraction modulates connectivity of the cingulo-frontal cortex and the midrain during pain--an MRI analysis显示文摘Valet M Sprenger T Boecker H 2004Pain2004,109,3:1
20Ductal epithelial proliferations of the breast: a biological continum? Comparative genomic hybridization and high-moleular-weight cytokeratin expression patterns显示文摘Boecker W Buerger H Schimitz K 2001J Pathol2001,195,:1
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