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| 1 | Crohn's disease environmental factors in the developing world: A case-control study in a statewide catchment area in Brazil显示文摘AIM To identify environmental risk factors associated with the development of Crohn's disease(CD) in order to reassess the hygiene hypothesis.METHODS A hospital-based, case-control study was carried out with CD patients(n = 145) and controls(n = 163)representing a socioeconomically diverse statewide catchment area in Brazil. Controls were recruited from caregivers of patients seen in different outpatient clinics at the same hospital. A multi-item survey with 94 questions regarding family history of CD, perinatal and childhood circumstances, living conditions, tobacco use and familial socioeconomic status was carried out by interviewers. RESULTS On the univariate analysis, predictive variables for CD included being male, under age of 40, a high education level, urban dweller, smaller family size, exposure to enteric pathogens and user of treated water(P < 0.005). On the multivariate analysis, variables significantly associated with CD were male gender(OR = 2.09), under age 40(OR = 3.10), white(OR = 2.32), from a small family in childhood(OR = 2.34) and adulthood(OR = 3.02), absence of viral infections in childhood(OR = 2.23), exposure to enteric pathogens(OR = 2.41), having had an appendectomy(OR = 2.47) and prior or current smoker(OR = 2.83/1.12). CONCLUSION Most variables supporting the 'hygiene hypothesis' are associated with the development of CD but are not independent predictors of the diagnosis. | Valéria Cristina Loureiro Salgado Ronir Raggio Luiz Neio Boechat Bianca C Schorr Isabella S Leao Tiago Nunes Cyrla Zaltman | 2017 | World Journal of Gastroenterology2017，23，30： | 2 |
| 2 | Estimated cumulative radiation dose from PET/CT in children with malignancies: a 5-year retrospective review显示文摘 | Soni C. Chawla Noah Federman Di Zhang Kristen Nagata Soujanya Nuthakki Michael McNitt-Gray M. Ines Boechat | 2010 | Pediatric Radiology2010，，： | 2 |
| 3 | Idiopathic infantile arterial calcification:imaging evaluation and the usefulness of MR angiography显示文摘 | Tran KH Boechat MI | 2006 | Pediatr Radiol2006，36，： | 1 |
| 4 | Cardiac MR ima ging and MR angiography for assessment of complex tetralogy of Fal|ot and pulmonary atresia 显示文摘 | Boechat MI Ratib O Williams PL | 2005 | Radiographics2005，，： | 1 |
| 5 | Transoralapproach to the craniovertebral junction 显示文摘 | Landeiro JA Boechat S Christoph Dde H | 2007 | Arq Neuropsiqu-iatr2007，65，： | 1 |
| 6 | Culture at high density improves the ability of human macrophages to control mycobacterial growth显示文摘 | Boechat N Bouchonnet F Bonay M | | 0，，10： | 1 |
| 7 | Symptoms prevalence amongoffice workers of a sealed versus a non-sealed building : associa-tions to indoor air quality 显示文摘 | Rios JL Boechat JL Gioda A | 2009 | Environ Int2009，35，8： | 1 |
| 8 | Transoral approach to the craniovertcbral junction显示文摘 | Landeim JA Boechat S Christeph Dde H | 2007 | Arq Neuropsiqu-iatr2007，65，： | 1 |
| 9 | The influence of a TNF gene polymorphism on the severity of rheuma- toid arthritis in the Brazilian Amazon 显示文摘 | BOECHAT A L BOECHAT NDE O OGUSKU M M | 2013 | Cytokine2013，61，2： | 1 |
| 10 | Coagulase gene polymorphism of Staphylococcus aureus isolated from goat mastitis in Brazilian Dairy Herds显示文摘 | Da Silva E R Boechat J U D Da Silva N | 2006 | Letters in Applied Microbiology2006，42，1： | 1 |
| 11 | The influence of a TNF gene polymorphism on the severity of rheumatoid arthritis in the Brazilian Amazon显示文摘 | Boechat AL Boechat Nde O Ogusku MM | 2013 | Cytokine2013，61，2： | 1 |
| 12 | Transoral approach to the craniovertebral junction显示文摘 | Landeiro JA Boechat S Christoph Dde H | 2007 | Arq Neuropsiqu-iatr2007，65，： | 1 |
| 13 | Impacts of fish farm pollution on ecosystem structure and function of tropical headwater streams 显示文摘 | Rosa R S Aguiar A C Boechat I G | 2013 | Environmental Pollution2013，174，： | 1 |
| 14 | Cardiac MR imaging and MR angiography for assessment of complex tetralogy o{ Fallot and pulmonary atresia 显示文摘 | BOECHAT M I RATIB O WILLIAMS P L | 2005 | Radiographics2005，25，6： | 1 |
| 15 | Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv ( ATCC 27294 ) strain显示文摘 | BOECHAT N FERREIRA V F FERREIRA S B | 2011 | J Med Chem2011，54，17： | 1 |
| 16 | Magnetic resonance imaging of abdominal and pelvic masses in children显示文摘 | Boechat M | 1990 | Top Magn Reson Imaging1990，3，： | 1 |
| 17 | The influence of a TNF gene polymorphism on the severity of rheumatoid arthritis in the Brazilian Amazon显示文摘 | Boechat AL Boechat Nde O Ogusku MM | 2013 | Cytokine2013，61，2： | 1 |
| 18 | Transoral approach to the craniovertebral junction 显示文摘 | Landeiro JA Boechat S Christoph DH | 2007 | Arq Neuropsiquiatr2007，65，4： | 1 |
| 19 | Cardiac MR imaging and MR angiography for assessment of complex tetralogy of Fallot and pulmonary atresia显示文摘 | Boechat MI Ratib O Williams PL | 2005 | Radiographics2005，25，6： | 1 |
| 20 | Cardiac MR imaging and MR angiography for assessment of complex tetralogy of Fallot and pulmonary atresia显示文摘 | Boechat MI Ratib O Williams PL | 2005 | Radiographics2005，25，6： | 1 |
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