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| 1 | Cardiac and non-cardiac causes of T-wave inversion in the precordial leads in adult subjects: A Dutch case series and review of the literature显示文摘AIM: To describe the electrocardiographic(ECG) phenomena characterized by T-wave inversion in the precordial leads in adults and to highlight its differential diagnosis. METHODS: A retrospective chart review of 8 adult patients who were admitted with ECG T-wave inversion in the anterior chest leads with or without prolongation of corrected QT(QTc) interval. They had different clinical conditions. Each patient underwent appropriate clinical assessment including investigation for myocardial involvement. Single and multimodality noninvasive, semi-invasive and invasive diagnostic approach were used to ascertain the diagnosis. The diagnostic assessment included biochemical investigation, cardiac and abdominal ultrasound, cerebral and chest computed tomography, nuclear medicine and coronary angiography.RESULTS: Eight adult subjects(5 females) with a mean age of 66 years(range 51 to 82) are analyzed. The etiology of T-wave inversion in the precordial leads were diverse. On admission, all patients had normal blood pressure and the ECG showed sinus rhythm. Five patients showed marked prolongation of the QTc interval. The longest QTc interval(639 ms) was found in the patient with pheochromocytoma. Giant T-wave inversion(≥ 10 mm) was found in pheochromocytoma followed by electroconvulsive therapy and finally ischemic heart disease. The deepest T-wave was measured in lead V3(5 ×). In 3 patients presented with mild T-wave inversion(patients 1, 5 and 4 mm), the QTc interval was not prolonged(432, 409 and 424 msec), respectively.CONCLUSION: T-wave inversion associated with or without QTc prolongation requires meticulous history taking, physical examination and tailored diagnostic modalities to reach rapid and correct diagnosis to establish appropriate therapeutic intervention. | Salah AM Said Rene Bloo Ramon de Nooijer Andries Slootweg | 2015 | World Journal of Cardiology2015，7，2： | 7 |
| 2 | Intensive insulin therapy and pentastarch resuscitation in severe sepsis显示文摘 | Brunkhorst FM Engel C Bloos F | | New England Journal of Medicine0，，： | 2 |
| 3 | Role of fiberoptic bronchosco- py in conjunction with the use of double-lumen tubes for thoracic anesthesia : a prospective study显示文摘 | Klein U Karzai W Bloos F | 1998 | Anesthesiology1998，88，2： | 1 |
| 4 | Intensive insulin therapy and pentastarch resuscitation in severe sepsis 显示文摘 | BRUNKHORST FM ENGEL C BLOOS F | 2008 | N Engl Med2008，358，2： | 1 |
| 5 | Intensive insul-in therapy and pentastarch resuscitation in severe sepsis显示文摘 | Brunkhorst FM Engel C Bloos F | 2008 | N Engl J Med2008，358，2： | 1 |
| 6 | Role of fiberoptic bronchoscopy in conjunction with the use of double-lumen tubes for thoracic anesthe- sia显示文摘 | Klein U Karzai W Bloos F | 1998 | Anesthesiology1998，88，2： | 1 |
| 7 | A role of fibreoptic bronchoscopy in conjunction with the use of double-lumen tubes for thoracic anesthesia 显示文摘 | Klein U Karrai W Bloos F | 1998 | Anesthesiology1998，88，2： | 1 |
| 8 | Role of fiberoptic bronchoscopy in conjunction with the use of double-lumen tubes for thoracic anesthesia:a prospective study显示文摘 | Klein U Karzai W Bloos F | 1998 | Anesthesiology1998，88，2： | 1 |
| 9 | A muhicenter trial to compare blood culture with polymerase chain reaction in severe human sepsis 显示文摘 | Bloos F Hinder F Becker K | 2010 | Intens Care Med2010，36，： | 1 |
| 10 | Effects of Staff Training on the Care of Mechanically Ventilated Patients:A Prospec- tive Cohort Study显示文摘 | Bloos F Mtiller S Harz A | 2009 | Br J Anaesth2009，103，2： | 1 |
| 11 | Muhinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study显示文摘 | Bloos F Marshall JC Dellinger RP | 2011 | Crit Care2011，15，2： | 1 |
| 12 | Intensive insulin therapy and pentastarch resuscitation in severe sepsis显示文摘 | Brunkhorst FM Engel C Bloos F | 2008 | N Engl J Med2008，358，2： | 1 |
| 13 | Multinational, observa- tional study of procalcitonin in ICU patients with pneumonia re- quiring mechanical ventilation: a multieenter observational study 显示文摘 | Bloos F Marshall JC Dellinger RP | 2011 | Crit Care2011，15，2： | 1 |
| 14 | Rapid diagnosis of sepsis 显示文摘 | Bloos F Reinhart K | 2014 | Virulence2014，5，1： | 1 |
| 15 | Multinational,ob- servational study of procalcitonin in ICU patients with pneumonia re- quiting mechanical ventilation: a multieemer observational study显示文摘 | BLOOS F MARSHALL JC DELLINGER RP | 2011 | Crit Care2011，15，2： | 1 |
| 16 | Role of Fiberoptic Bronchoscopy in Conjunction with the Use of Double-lumenTubes for Thoracis Anesthesia:A Prospective Study显示文摘 | Klein U Karzai W Bloos F | 1998 | Anesthesiology1998，88，2： | 1 |
| 17 | Multinational,observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation:a multicenter observational study显示文摘 | Bloos F Marshall JC Dellinger RP | 2011 | Crit Care2011，15，2： | 1 |
| 18 | Role of fiberoptic bronchoscopy in conjunction with the use of double-lumen tubes for thoracic anesthesia显示文摘 | Klein U Karzai W Bloos F | 2003 | Anesthesiology2003，88，2： | 1 |
| 19 | Role of fiberoptic bronchos-racic anesthesia:a prospective study显示文摘 | Klein U Karzai W Bloos F | 1998 | Anesthesiology1998，88，2： | 1 |
| 20 | Intensive insulin therapy and pentastarch resuscitationin severe sepsis显示文摘 | Brunkhorst FM Engel C Bloos F | | 0，，： | 1 |
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