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64篇 您的检索式:作者名="Blix"
    题名 作者 年代 出处 被引量
1The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells显示文摘Streptococcus mitis(S. mitis) is a pioneer commensal bacterial species colonizing many of the surfaces of the oral cavity in healthy individuals. Yet, not much information is available regarding its interaction with the host. We used examination of its transcriptional regulation in oral keratinocytes to elucidate some of its potential roles in the oral cavity. Transcription factor analysis of oral keratinocytes predicted S. mitis-mediated activation of aryl hydrocarbon receptor(Ah R). Activation and functionality of Ah R was confirmed through nuclear translocation determined by immunofluorescence microscopy and real-time polymerase chain reaction with reverse transcription analysis of CYP1A1, the hallmark gene for Ah R activation. Addition of Streptococcus mutans or Streptococcus gordonii did not induce CYP1A1 transcription in the keratinocyte cultures. Introduction of an Ah R-specific inhibitor revealed that S. mitis-mediated transcription of CXCL2 and CXCL8 was regulated by Ah R. Elevated levels of prostaglandin E2(enzyme-linked immunosorbent assay) in supernatants from S. mitis-treated oral epithelial cells were also attenuated by inhibition of Ah R activity. The observed Ah R-regulated activities point to a contribution of S. mitis in the regulation of inflammatory responses and thereby to wound healing in the oral cavity. The concept that the oral commensal microbiota can induce Ah R activation is important, also in view of the role that Ah R has in modulation of T-cell differentiation and as an anti-inflammatory factor in macrophages.stian a engen gro h rørvik olav schreurs inger js blix karl schenck 2017International Journal of Oral Science2017,9,3:2
2What is the duration of normal labour显示文摘Blix E Kumle M Oian P 2008Tidsskr Nor Laegeforen2008,12,:1
3Episiotomy characteristics and risks for obstetric anal sphincter injuries: a case-control study显示文摘Stedenfeldt M Pirhonen J Blix E 2012BJOG2012,119,6:1
4Avoiding disturbance: midwifery practice in home birth settings in Norway 显示文摘Blix E 2011Midwifery2011,27,:1
5Characteristics of drug-related problems discussed by hospital pharmacists in multidisciplinary teams显示文摘Hege Salvesen Blix Kirsten K. Viktil Tron Anders Moger ?smund Reikvam 2006Pharmacy World & Science2006,,3:1
6Review of the use of defined daily dose concept in drug utilisation research in China 显示文摘Teng L Xin HW Blix HS 2012Pharmaeoepidemiol Drug SM2012,21,10:1
7Methadone Maintenance programs in Sweden 显示文摘Blix 0 2002JA-MA2002,261,15:1
8Agricultural land use in life cycle assessment (LCA):case studies of three vegetable oil crops显示文摘Berit Mattsson Christel Cederberg Lisa Blix 2000Journal of Cleaner Production2000,,8:1
9Proposed nomenclature in the field of aeuraminic and sialie acid显示文摘BLIX G GOTTSCHARLK A KLENK E 1957Nature1957,179,:1
10Methadone Maintenance Programs in Sweden显示文摘Blix O 1989JAMA1989,261,15:1
11Infant feeding in relation to islet autoimmunity and type 1 diabetes in genetically susceptible children : the MIDIA Study 显示文摘Lund - Blix NA Stene LC Rasmussen T 2015Diabetes Care2015,38,2:1
12Review of the use of defined daily dose concept in drug utilisation research in China显示文摘Teng L Xin HW Blix HS 2012Pharmacoepidemiol Drug Saf2012,21,10:1
13Occupational stress among university teachers显示文摘Blix A G Cruise R J Mitchell B M 0,,2:1
14Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems显示文摘Viktil KK Blix HS Moger TA 2007Br J Clin Pharmacol2007,63,2:1
15Anal incontinence, urinary in- eontinence and sexual problems in primiparous women - a comparison between women with episiotomy only and women with episiotomy and ob- stetric anal sphincter injury显示文摘Stedenfeldt M Pirhonen J Blix E 2014BMC Womeus Health2014,14,:1
16Proposed nomenclature in the field of neuraminic and siallc acids 显示文摘Blix F G Gottschalk A Klenk E 1957Nature1957,179,:1
17Methadone maintenance programs in Sweden显示文摘 1989JAMA1989,261,15:1
18Agricultural Land-use in Life Cycle Assessment (LCA): Case Studies of Three Vegetable Oil Crops显示文摘Mattsson B Cederberg C Blix L 2000Journal of Cleaner Production2000,8,:1
19Prognostic value of the labour admission test and its effectiveness compared with auscultation only: a systematic review 显示文摘Blix E Reiner LM Klovning A 2005BJOG2005,112,12:1
20White blood cell count measured prior to cancer development is associated with future risk of venous thromboembolism-the tromsqb study显示文摘Blix K Jensvoll H Braekkan SK 2013PLoS ONE2013,8,73:1
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