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| 1 | Expression of PEA3/ E1AF/ ETV4,an Ets-related transcription factor,in breast tumors:positive links to MMP2,NRG1 and CGB expression显示文摘 | Bièche I Tozlu S Girault I | 2004 | Carcinogenesis2004，25，3： | 1 |
| 2 | Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection显示文摘 | Bièche I Asselah T Laurendeau I | | 0，，01： | 1 |
| 3 | In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C显示文摘 | Asselah T Bièche I Mansouri A | | 0，，03： | 1 |
| 4 | Molecular pro-filing of inflamma-tory breast cancer:identification of a poor-prognosis gene expression signature显示文摘 | Bièche I Lerebours F Tozlu S | | 0，，： | 1 |
| 5 | Gene expression study of Aurora-A reveals implication during bladder carcinogenesis implication during bladder carcinogenesis urothelial cancer显示文摘 | Compérat E Bièche I Dargère D | 2008 | Urology2008，72，4： | 1 |
| 6 | Overexpression of the stathmin gene in a subset of human breast cancer显示文摘 | Bièche I Lachkar S Becette V | 1998 | Br J Cancer1998，78，6： | 1 |
| 7 | SWI/SNF chromatin remodeling and human malignancies显示文摘 | MASLIAH-PLANCHON J BIèCHE I GUINEBRETIèRE JM | 2015 | Annu Rev Pathol2015，10，1： | 1 |
| 8 | Identification of novel gene expression targets for the Ras association domain family 1A (RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma显示文摘 | Agathanggelou A Bièche I Ahmed-Choudhury J | 2003 | Cancer Res2003，63，17： | 1 |
| 9 | Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin Ⅱ AT2 receptor-interacting proteins, ATIP 显示文摘 | Di Benedetto M Bièche I Deshayes F | 2006 | Gene2006，380，2： | 1 |
| 10 | Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma显示文摘 | Bièche I Girault I Urbain E Tozlu S Lidereau R | | 0，，03： | 1 |
| 11 | Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay显示文摘 | Bièche I Noguès C Paradis V | 2000 | Clini Cancer Res2000，6，2： | 1 |
| 12 | 巴德-基亚里综合征的定量基因表达:一项分子学发病机制显示文摘Background: Budd-Chiari syndrome (BCS) is associated with parenchymal changes leading to major architecture remodelling. In order to gain further insight int o the pathogenesis of BCS, we investigated expression of a set of genes involved in the course of chronic liver diseases. Methods: Quantitative expression of 35 selected genes involved in extracellular matrix regulation, growth factors, and angiogenesis was investigated in 13 cases of BCS and compared with 10 normal li vers and 13 cirrhosis cases by real time reverse transcription-polymerase chain reaction. Differential gene expression was considered significant for genes sho wing at least a two-fold variation, with p< 0.05. Results: Expression of 14 gen es was significantly increased in BCS versus normal liver, with the highest incr ease in superior cervical ganglion 10 (SCG10) gene. BCS cases were classified ac cording to their evolution and morphological pattern as either acute or chronic in six and seven cases, respectively. Unsupervised hierarchical clustering of ac ute and chronic BCS cases on the basis of similarity in gene expression pattern led to distinction between the two groups. Expression of three genes was signifi cantly different in acute versus chronic BCS (increase in matrix metalloproteina se 7 and SCG10, decrease in thrombospondin-1 for chronic BCS). Seventeen and 10 genes, mainly involved in extracellular matrix and vascular remodelling, were s ignificantly deregulated in acute BCS versus normal liver and cirrhosis, respect ively. Conclusion: These results show that BCS cases display a specific gene exp ression profile that is different from that of normal liver and cirrhosis; the m olecular configuration of BCS can be readily distinguished by its evolution and morphological pattern. | Paradis V Bièche I Dargère D. 郑世成 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，0，4： | 0 |
| 13 | Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues显示文摘 | Ivan Bièche Cèline Narjoz Tarik Asselah Sophie Vacher Patrick Marcellin Rosette Lidereau Philippe Beaune Isabelle de Waziers | 2007 | Pharmacogenetics and Genomics2007，，9： | 1 |
| 14 | Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection显示文摘 | Ivan Bièche Tarik Asselah Ingrid Laurendeau Dominique Vidaud Claude Degot Valérie Paradis Pierre Bedossa Dominique-Charles Valla Patrick Marcellin Michel Vidaud | 2004 | Virology2004，，1： | 1 |
| 15 | Liver Gene Expression Signature of Mild Fibrosis in Patients With Chronic Hepatitis C显示文摘 | Tarik Asselah Ivan Bièche Ingrid Laurendeau Valérie Paradis Dominique Vidaud Claude Degott Michelle Martinot Pierre Bedossa Dominique Valla Michel Vidaud Patrick Marcellin | 2005 | Gastroenterology2005，，6： | 1 |
| 16 | Telangiectatic focal nodular hyperplasia: a variant of hepatocellular adenoma显示文摘 | Valerie Paradis Asmae Benzekri Delphine Dargère Ivan Bièche Ingrid Laurendeau Valerie Vilgrain Jacques Belghiti Michel Vidaud Claude Degott Pierre Bedossa | 2004 | Gastroenterology2004，，5： | 1 |
| 17 | Liver Gene Expression Signature of Mild Fibrosis in Patients With Chronic Hepatitis C显示文摘 | Tarik Asselah Ivan Bièche Ingrid Laurendeau Valérie Paradis Dominique Vidaud Claude Degott Michelle Martinot Pierre Bedossa Dominique Valla Michel Vidaud Patrick Marcellin | 2005 | Gastroenterology2005，，6： | 1 |
| 18 | IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C显示文摘 | Tarik Asselah Simon De Muynck Philippe Bro?t Julien Masliah-Planchon Maud Blanluet Ivan Bièche Martine Lapalus Michelle Martinot-Peignoux Olivier Lada Emilie Estrabaud Qian Zhang Ahmed El Ray Dominique Vidaud Marie-Pierre Ripault Nathalie Boyer Pierre Bed | 2011 | Journal of Hepatology2011，，3： | 1 |
| 19 | Cortical branched actin determines cell cycle progression显示文摘The actin cytoskeleton generates and senses forces. Here we report that branched actin networks from the cell cortex depend on ARPC1B-containing Arp2/3 complexes and that they are specifically monitored by type I coronins to control cell cycle progression in mammary epithelial cells. Cortical ARPC1B-dependent branched actin networks are regulated by the RAC1/WAVE/ARPIN pathway and drive lamellipodial protrusions. Accordingly, we uncover that the duration of the G1 phase scales with migration persistence in single migrating cells. Moreover, cortical branched actin more generally determines S-phase entry by integrating soluble stimuli such as growth factors and mechanotransduction signals, ensuing from substratum rigidity or stretching of epithelial monolayers. Many tumour cells lose this dependence for cortical branched actin. But the RAC1-transformed tumour cells stop cycling upon Arp2/3 inhibition. Among all genes encoding Arp2/3 subunits, ARPC1B overexpression in tumours is associated with the poorest metastasis-free survival in breast cancer patients. Arp2/3 specificity may thus provide diagnostic and therapeutic opportunities in cancer. | Nicolas Molinie Svetlana N. Rubtsova Artem Fokin Sai P. Visweshwaran Nathalie Rocques Anna Polesskaya Anne Schnitzler Sophie Vacher Evgeny V. Denisov Lubov A. Tashireva Vladimir M. Perelmuter Nadezhda V. Cherdyntseva Ivan Bièche Alexis M. Gautreau | 2019 | Cell Research2019，29，6： | 0 |
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