|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Heteroscorpionate-based Co2+, Zn2+, and Cu2+ complexes: coordination behavior, aerobic oxidation, and hydrogen sulfide detection显示文摘 | Strianese M Milione S Bertolasi V | 2011 | Inorg Chem2011,50,3: | 1 |
| 2 | Somatosensory disinhibition in dystonia显示文摘 | Frasson E Priori A Bertolasi L | 2001 | Mov Disord2001,16,4: | 1 |
| 3 | Somatosensory disinhibition in dystonia显示文摘 | Frasson E Priori A Bertolasi L | 2001 | Mov Disord2001,16,4: | 1 |
| 4 | Functional analysis of peach ACC oxidase promoters in transgenic tomato and in ripening peach fruit显示文摘 | RASORI A BERTOLASI B FURINI A | 2003 | Plant Science2003,165,3: | 1 |
| 5 | Sympathetic skin response asymmetry in early stage idiopathic Parkinson's disease 显示文摘 | FUSINA S CONTE S BERTOLASI L | 1999 | Clin Nenrophysiol1999,110,2: | 1 |
| 6 | Synthesis and photophysical properties of a trans-biscyclometalated complex containing the Terdentate hgand 2,6-Diphenylpyridine 显示文摘 | POLSON M FRACASSO S BERTOLASI V | 2004 | Inorg Chem2004,43,6: | 1 |
| 7 | The role of muscle biopsy in investigating isolated muscle pain显示文摘 | M Filosto P Tonin G Vattemi L Bertolasi A Simonati N Rizzuto G Tomelleri | 2007 | Neurology2007,,3: | 1 |
| 8 | Ti- tanium complexes bearing a hemilabile heteroscorpionate ligand : Synthesis, reactivity, and olefin polymer- ization activity显示文摘 | MILIONE S BERTOLASI V CUENCA T | 2005 | Organometallics2005,24,21: | 1 |
| 9 | Iridium cyclometalated complexes with axial symmetry: Synthesis and photophysical properties of a trans-biscyclometalated complex containing the terdentate ligand 2,6-diphenylpyridine 显示文摘 | POLSON M FRACASSO S BERTOLASI V | 2004 | Inorg Chem2004,43,6: | 1 |
| 10 | Enantioselective inclusion in bile acids : resolution of cyclic ketones 显示文摘 | Valerio Bertolasi Olga Bortolini Marco Fogagnolo | 2001 | Tetrahedron : Asymme Trym2001,,12: | 1 |
| 11 | 查看详情显示文摘 | Dondoni A Massi A Minghini E Bertolasi V | | 0,,: | 1 |
| 12 | Sympathetic skin response asymmetry in early stage idiopathic Parkinson's disease显示文摘 | Fusina S Conte S Bertolasi L | 1999 | Clin Neurophysiol1999,110,2: | 1 |
| 13 | Timing of tactile and visuo-tactile events is impaired in patients with cervical dystonia显示文摘 | Tinazzi M Fiorio M Bertolasi L | | 0,,: | 1 |
| 14 | Functional analysis ofpeach ACC oxidase promoters in transgenic tomato and in ripening peach fruit显示文摘 | Rasori A Bertolasi B Furini A | 2003 | Plant Science2003,165,: | 1 |
| 15 | Abnormal central integration of a dual somatosensory input in dystonia显示文摘 | Tinazzi M Priori A Bertolasi L | 2000 | Brain2000,123,1: | 1 |
| 16 | Abnormal central integration of a dual somatosensory input in dystonia Evidence for sensory overflow显示文摘 | Tinazzi M Priori A Bertolasi L | 2000 | Brain2000,123,1: | 1 |
| 17 | Functional analysis of peach ACC oxidase promoters in transgenic tomato and in ripening peach fruit显示文摘 | Rasori A Bertolasi B Furini A | | 0,,: | 1 |
| 18 | Olfactory swab sampling optimization for α-synuclein aggregate detection in patients with Parkinson’s disease显示文摘Background: In patients with Parkinson’s disease (PD), real-time quaking-induced conversion (RT-QuIC) detection of pathological α-synuclein (α-syn) in olfactory mucosa (OM) is not as accurate as in other α-synucleinopathies. It is unknown whether these variable results might be related to a different distribution of pathological α-syn in OM. Thus, we investigated whether nasal swab (NS) performed in areas with a different coverage by olfactory neuroepithelium, such as agger nasi (AN) and middle turbinate (MT), might affect the detection of pathological α-syn. Methods: NS was performed in 66 patients with PD and 29 non-PD between September 2018 and April 2021. In 43 patients, cerebrospinal fluid (CSF) was also obtained and all samples were analyzed by RT-QuIC for α-syn. Results: In the first round, 72 OM samples were collected by NS, from AN (NSAN) or from MT (NSMT), and 35 resulted positive for α-syn RT-QuIC, including 27/32 (84%) from AN, 5/11 (45%) from MT, and 3/29 (10%) belonging to the non-PD patients. Furthermore, 23 additional PD patients underwent NS at both AN and MT, and RT-QuIC revealed α-syn positive in 18/23 (78%) NSAN samples and in 10/23 (44%) NSMT samples. Immunocytochemistry of NS prepara-tions showed a higher representation of olfactory neural cells in NSAN compared to NSMT. We also observed α-syn and phospho-α-syn deposits in NS from PD patients but not in controls. Finally, RT-QuIC was positive in 22/24 CSF samples from PD patients (92%) and in 1/19 non-PD. Conclusion: In PD patients, RT-QuIC sensitivity is significantly increased (from 45% to 84%) when NS is performed at AN, indicating that α-syn aggregates are preferentially detected in olfactory areas with higher concentration of olfactory neurons. Although RT-QuIC analysis of CSF showed a higher diagnostic accuracy compared to NS, due to the non-invasiveness, NS might be considered as an ancillary procedure for PD diagnosis. | Matilde Bongianni Mauro Catalan Daniela Perra Elena Fontana Francesco Janes Claudio Bertolotti Luca Sacchetto Stefano Capaldi Matteo Tagliapietra Paola Polverino Valentina Tommasini Giulia Bellavita Elham Ataie Kachoie Roberto Baruca Andrea Bernardini Mariarosaria Valente Michele Fiorini Erika Bronzato Stefano Tamburin Laura Bertolasi Lorenzo Brozzetti Maria Paola Cecchini Gianluigi Gigli Salvatore Monaco Paolo Manganotti Gianluigi Zanusso | 2022 | Translational Neurodegeneration2022,11,1: | 1 |
| 19 | Sympathetic skin response asymmetry in early stage idiopathic Parkinson’s disease 显示文摘 | Fusina S Conte S Bertolasi L | 1999 | Clin Neurophysiol1999,110,: | 1 |
| 20 | Temporal processing of visuotaetile and tactile stimuli in writer's eramp显示文摘 | Fiorio M Tinazzi M Bertolasi L | 2003 | Ann Neu- rol2003,53,5: | 1 |