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| 1 | Accuracy and responses of genomic selection on key traits in apple breeding显示文摘The application of genomic selection in fruit tree crops is expected to enhance breeding eficiency by increasing prediction accuracy,increasing selection intensity and decreasing generation interval.The objectives of this study were to assess the accuracy of prediction and selection response in commercial apple breeding programmes for key traits.The training population comprised 977 individuals derived from 20 pedigreed fllsib families.Historic phenotypic data were available on 10 traits related to productivity and fruit external appearance and genotypic data for 7829 SNPs obtained with an llumina 20K SNP array.From these data,a genome-wide prediction model was built and subsequently used to calculate genomic breeding values of five application fllsib families.The application families had genotypes at 364 SNPs from a dedicated 512 SNP array,and these genotypic data were extended to the high-density level by imputation.These five families were phenotyped for 1 year and their phenotypes were compared to the predicted breeding values.Accuracy of genomic prediction across the 10 traits reached a maximum value of 0.5 and had a median value of 0.19.The accuracies were strongly affected by the phenotypic distribution and heritability of traits.In the largest family,significant selection response was observed for traits with high heritability and symmetric phenotypic distribution.Traits that showed non-significant response often had reduced and skewed phenotypic variation or low heritability.Among the five application families the accuracies were uncorrelated to the degree of relatedness to the training population.The results underline the potential of genomic prediction to accelerate breeding progress in outbred fruit tree crops that still need to overcome long generation intervals and extensive phenotyping costs. | Hélène Muranty Michela Troggio Inès Ben Sadok Mehdi Al Rifaï Annemarie Auwerkerken Elisa Banchi Riccardo Velasco Piergiorgio Stevanato W.Eric van de Weg Mario Di Guardo Satish Kumar François Laurens Marco C.A.M.Bink | 2015 | Horticulture Research2015，2，1： | 14 |
| 2 | ExtraperitoneaL Laparoscopic repair of ureteropeLvic junction obstruction:initiaL experience in 15 cases显示文摘 | Ben SLama M R SaLomon L Hoznek A et aL | 2000 | UroLogy2000，56，： | 1 |
| 3 | The knoevenagel condensa- tion of aromatic aldehydes with malononitrile of ethyl cyano- acetate in the presence of CTMAB in water显示文摘 | Wang S Ben Z Cao W ct al | 2001 | Synth Com- mun2001，31，5： | 1 |
| 4 | The International Criteria for Beh?et’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria显示文摘 | F. Davatchi S. Assaad‐Khalil K.T. Calamia J.E. Crook B. Sadeghi‐Abdollahi M. Schirmer T. Tzellos C.C. Zouboulis M. Akhlagi A. Al‐Dalaan Z.S. Alekberova A.A. Ali A. Altenburg E. Arromdee M. Baltaci M. Bastos S. Benamour I. Ben Ghorbel A. Boyvat L. Carvalho | 2014 | J Eur Acad Dermatol Venereol2014，，3： | 1 |
| 5 | Polyphasic study ofthe spalial dislribulion of microorgan -isms in mexican pozol, afermented maize dough,demonstrates the need for cultivation -independent methods to investigate traditional fermentations 显示文摘 | Ampe b\ Ben Omar N Moizan C el al | 1999 | Applied and Environmental Microbiology1999，，65： | 1 |
| 6 | Role of anti-tumor necrosis factor-alpha in ischemia/reperfusion injmy in isolated rat pancreas in a blood free environment显示文摘 | Hochhansor E Burstein L el al | 2002 | Transplauaion2002，73，12： | 1 |
| 7 | ,von Schulz,,Rojas Matas,Early reperfusion and late clinical outcomes in patients presenting with acute myocardial infarction randomly assigned to primary percutaneous coronary intervention or streptokinase显示文摘 | Berrocal D H Cohen M G Spinetta A D Ben M G C A Gabay J M Magni J M Nogareda G Oberti P C et al Am Heart J E22 | | 0，，： | 1 |
| 8 | Male breast cancer:about 123 cases collected at the Institate Salah-Azaiz of Tunis from 1979 to 1999显示文摘 | Ben Dhiab T Bouzid T Gamoudi A er al | 2005 | Bull Cancer2005，92，3： | 1 |
| 9 | The Tetrad BMI, Leptin, Leptin/Adiponectin (L/A) Ratio and CA 15‐3 are Reliable Biomarkers of Breast Cancer显示文摘 | Jonnathan G. Santillán‐Benítez Hugo Mendieta‐Zerón Leobardo M. Gómez‐Oliván Juan J. Torres‐Juárez Juan M. González‐Ba?ales Lorena V. Hernández‐Pe?a Angel Ordó?ez‐Quiroz | 2013 | J Clin Lab Anal2013，，1： | 1 |
| 10 | Early age-related changes in adult hippocampal neurogenesis in C57mice显示文摘 | Ben Abdallah NM Slomianka L Vyssotski AL | 2010 | Neurobiology of Aging2010，31，1： | 1 |
| 11 | How to protect liver graft with nitric oxide显示文摘 | Ben Abotennebi H Zaouali MA Alfany-Fernandez 1 et al | 2011 | World J Gastroenterol2011，17，24： | 1 |
| 12 | Cerebral glucose utili- zation and platelet mitoehondrial coroplex I activity in schizophreni- a : A FDG - PET study显示文摘 | Ben Shachar D Bonne O Chisin R el al | 2007 | Prog Neurol~sychophannaeol Biol Psy- chiatry2007，31，4： | 1 |
| 13 | Occurrence of a variant of cucumber green mottle mosaic virus in Israel 显示文摘 | Antigus Y Pearslman M Ben -Yoseph R e t al | 1990 | Phyto- parasitica1990，18，1： | 1 |
| 14 | Non-alcohol syndrome: a M, Cont i ic fatty hepatic consequence of common metabolic diseases显示文摘 | Ange 1 R et liver ico F De1 Ben al | 2003 | GastroenterolHepatol2003，18，： | 1 |
| 15 | Erosion of the telomericsingle-strand overhang at replicative senescence显示文摘 | Stewart SA’Ben Porath I Carey VJ ei al | 2003 | NatGenet2003，33，4： | 1 |
| 16 | Phenotypic and molecular epidemiology of Acinetobacter baumannli strains isolated in Rabta Hospital, Tunisia 显示文摘 | BEN OTHMAN A ZRIBI M MASMOUDI A ct al | 2007 | Arch Inst Pasteur Tunis2007，84，14： | 1 |
| 17 | Pancreatic pseudoeyst in children: what is the best therapeutic approach?显示文摘 | Nouira F Ben Ahmed Y SalTai N el al | 2011 | Arch Fedialr2011，8，11： | 1 |
| 18 | Induction of Myc-intron-binding polypeptides MIBP1 and RFX1 during retinoic acid-mediated differentiation of haemopoietic cells显示文摘 | Zajac KM Ben BN Kastanos E et al | 2000 | Biochem J2000，345，： | 1 |
| 19 | Case report : Primary pure squamous cell carcinoma of the gallbladder 显示文摘 | Rekik W Ben Fadhel C Boufaroua AL | 2011 | J Visc Surg2011，148，2： | 1 |
| 20 | Report of thirteen cases显示文摘 | Sauvage P Grimault L Ben Salem D et aL Lumbar intraspinal syno- vial cysts : imaging and treatment by percutaneous injection | 2000 | J Radiol2000，1，： | 1 |
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