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| 1 | Nat Chem Biol:利用CRISPR-Cas9激活细菌中沉默的基因簇,有望发现新的药物显示文摘为了抵抗疾病,很多医药库中的武器是从细菌当中获得的。如今,利用CRISPR-Cas9基因编辑技术。研究人员揭示出沉默基因中隐藏着的更多潜在的宝藏。作为一类常见的细菌。链霉菌被用来产生很多作为抗生素、抗癌试剂和其他药物的化合物。在一项新的研究中。来自美国伊利诺伊大学和新加坡科技研究局的研究人员利用CRISPR-Cas9技术激活链霉菌中不表达的或者说沉默的基因簇。 | Mingzi M Zhang, Wan Lin Yeo, Ee Lui Ang, Huimin Zhao Fong Tian Wong, Elena Heng Yajie Wang, Shangwen Luo, Ryan E Cobb, Behnam Enghiad, Huimin Zhao Yee Hwee Lim | 2017 | 现代生物医学进展2017,17,17: | 12 |
| 2 | Smac is required for cytochrome C - induced apoptosis in prostate cancer LNCaP cells 显示文摘 | Carson JP Behnam M Jennifer N | 2002 | Cancer Research2002,62,: | 1 |
| 3 | Effect of Noise Factors in Energy Management of Series Plug-in Hybrid Electric Vehicles显示文摘 | SHAMS-ZAHRAEI M KOUZANI A Z BEHNAM G | 2011 | International Review of Electrical Engineering2011,6,4: | 1 |
| 4 | Effectsof Infantile Repeated Hyperglycemia on Neuronal Density ofHippocampus and Pentylentetrazol Induced Convulsions inMale Wistar Rats显示文摘 | Moghadami M’Moghimi A Behnam'Rasouli M | 2012 | Iran J Basic Med Sci2012,15,4: | 1 |
| 5 | Directional Antenna Multipath Location Aided Routing(DA-MLAR)显示文摘 | SANJAYA G WANGT Limin BEHNAM M | 2006 | IEEE2006,,05: | 1 |
| 6 | Scheduling analysis of flexible job shop system by improved gravitational search algorithm 显示文摘 | BEHNAM B HOMAYUN M MOTAHAREH Z | 2012 | African Journal of Business Management2012,6,23: | 1 |
| 7 | An analysis of net energy production and feedstock availability for biobutanol and bioethanol显示文摘 | Swana J Yang Y Behnam M etal | 2011 | Bioresou roe Tech nology2011,102,2: | 1 |
| 8 | Reliable Design of aLogistics Network under Uncertainty : A Fuzzy Possibilitic-queuing Model显示文摘 | Behnam V Reza T M Fariborz J | 2013 | Applied Mathematical Modeling2013,,37: | 1 |
| 9 | Imperialist competitive algorithm for solving non-convex dynamic economic power dispatch 显示文摘 | Behnam M Abbas R Alireza S | 2012 | Energy2012,44,1: | 1 |
| 10 | Tandem oxidation process using eerie ammonium nitrate: Three-compo- nent synthesis of trisubstituted imidazdes under aero- bic oxidation conditions 显示文摘 | Shaabani A Maleki A Behnam M | 2009 | Synth Commtm2009,39,1: | 1 |
| 11 | Primary ovarian undifferentiated non-small cell carcinoma, neuroendocrine type 显示文摘 | Behnam K Kabus D Behnam M | 2004 | Gynecol Oneol2004,92,1: | 1 |
| 12 | CAD/CAM system selection: A multi-eomponent hybrid fuzzy MCDM显示文摘 | Roshanaei V Behnam Vahdani Mousavi S M | 2013 | Arabian Journal of Science and Engineering2013,38,: | 1 |
| 13 | Steady-State modeling of electroultrafiltration at constant concentration 显示文摘 | Radovich J M Behnam B M C | 1985 | Separation Science and Technology1985,20,4: | 1 |
| 14 | Inkjet printing technology for increasing the I/O density of 3D TSV interposers显示文摘Interposers with through-silicon vias(TSVs)play a key role in the three-dimensional integration and packaging of integrated circuits and microelectromechanical systems.In the current practice of fabricating interposers,solder balls are placed next to the vias;however,this approach requires a large foot print for the input/output(I/O)connections.Therefore,in this study,we investigate the possibility of placing the solder balls directly on top of the vias,thereby enabling a smaller pitch between the solder balls and an increased density of the I/O connections.To reach this goal,inkjet printing(that is,piezo and super inkjet)was used to successfully fill and planarize hollow metal TSVs with a dielectric polymer.The under bump metallization(UBM)pads were also successfully printed with inkjet technology on top of the polymer-filled vias,using either Ag or Au inks.The reliability of the TSV interposers was investigated by a temperature cycling stress test(−40℃ to+125℃).The stress test showed no impact on DC resistance of the TSVs;however,shrinkage and delamination of the polymer was observed,along with some micro-cracks in the UBM pads.For proof of concept,SnAgCu-based solder balls were jetted on the UBM pads. | Behnam Khorramdel Jessica Liljeholm Mika-Matti Laurila Toni Lammi Gustaf Mårtensson Thorbjörn Ebefors Frank Niklaus Matti Mäntysalo | 2017 | Microsystems & Nanoengineering2017,3,1: | 1 |
| 15 | A new approach to fixed bed radial heat transfer modeling using velocity fields from com- putational fluid dynamics simulations显示文摘 | BEHNAM M DIXON A G NIJEMEISLAND M | 2013 | Indus- trial Engineering Chemistry Research2013,52,15: | 1 |
| 16 | the effect ofrepetitive spreading depression on neuronal damage in juvenilerat brain 显示文摘 | JAFARIAN M RAHIMI S BEHNAM F | 2010 | Neuroscience2010,169,1: | 1 |
| 17 | Effect of cooling rate on microstructure and mechanical properties of gray cast iron 显示文摘 | M M J Behnam P Davami N Varahrarm | 2010 | Materials Science and Engineering2010,528,2: | 1 |
| 18 | Steady-State modeling of electrouhrafihration at constant concentration 显示文摘 | Radovich J M Behnam B M C | 1985 | Separation Science and Technology1985,20,4: | 1 |
| 19 | BMP binding peptide:a BMP-2 enhancing factor deduced from the sequence of native bovine bone morphogenetic protein/non-collagenous protein显示文摘 | Behnam K Phillips M L Silva J D | 2005 | Journal of Orthopaedic Research2005,23,1: | 1 |
| 20 | Reliable design of a logis- tics network under uncertainty: A fuzzy possibilitic - queuing model 显示文摘 | BEHNAM V REZA T M FARIBORZ J | 2013 | Applied Mathematical Modeling2013,,37: | 1 |