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| 1 | 查看详情显示文摘 | Derbyshire F J De Beer V H J Abotsi G M K Scaroni A W, Solar J M, Skrovanek D J | | 0，，： | 2 |
| 2 | Central line-associated bloodstream infection among children with biliary atresia listed for liver transplantation显示文摘BACKGROUND Pre-transplant nutrition is a key driver of outcomes following liver transplantation in children.Patients with biliary atresia(BA) may have difficulty achieving satisfactory weight gain with enteral nutrition alone,and parenteral nutrition(PN) may be indicated.While PN has been shown to improve anthropometric parameters of children with BA listed for liver transplantation,less is known about the risks,particularly infectious,associated with this therapy among this specific group of patients.AIM To describe the incidence,microbiology,and risk factors of central line-associated bloodstream infection(CLABSI) among children with BA listed for liver transplantation.METHODS Retrospective review of children aged ≤ 2-years of age with BA who were listed for primary liver transplantation at Texas Children's Hospital from 2008 through2015(n = 96).Patients with a central line for administration of PN(n = 63) were identified and details of each CLABSI event were abstracted.We compared the group of patients who experienced CLABSI to the group who did not,to determine whether demographic,clinical,or laboratory factors correlated with development of CLABSI.RESULTS Nineteen of 63 patients(30%,95%CI:19,43) experienced 29 episodes of CLABSI during 4800 line days(6.04 CLABSI per 1000 line days).CLABSI was predominantly associated with Gram-negative organisms(14/29 episodes,48%)including Klebsiella spp.,Enterobacter spp.,and Escherichia coli.The sole polymicrobial infection grew Enterobacter cloacae and Klebsiella pneumoniae.Grampositive organisms(all Staphylococcus spp.) and fungus(all Candida spp.)comprised 9/29(31%) and 6/29(21%) episodes,respectively.No demographic,clinical,or laboratory factors were significantly associated with an increased risk for the first CLABSI event in Cox proportional hazards regression analysis CONCLUSION There is substantial risk for CLABSI among children with BA listed for liver transplantation.No clinical,demographic,or laboratory factor we tested emerged as an independent predictor of CLABSI.While our data did not show an impact of CLABSI on the short-term clinical outcome,it would seem prudent to implement CLABSI reduction strategies in this population to the extent that each CLABSI event represents potentially preventable hospitalization,unnecessary healthcare dollar expenditures,and may exact an opportunity cost,in terms of missed allograft offers. | Nicole D Triggs Stacey Beer Sonam Mokha Kat Hosek Danielle Guffey Charles G Minard Flor M Munoz Ryan W Himes | 2019 | World Journal of Hepatology2019，11，2： | 2 |
| 3 | Successful knowledge management projects显示文摘 | Davenport T T De Long D W Beers M C | 1998 | Sloan Management Review1998，，11： | 2 |
| 4 | Creep cavitations by vacancy diffusion in plastically deforming solid显示文摘 | BEERE D SPEIGHT M V | 1978 | Metal Science1978，12，： | 1 |
| 5 | Quantitative real- time PCR assay for determining transgene copy num- ber in transformed plants 显示文摘 | Ingham D J Beer S Money S | 2001 | Bioteehniques2001，31，1： | 1 |
| 6 | Anion Recognition and Sensing:The State of the Art and Future Perspectives显示文摘 | Beer P D and Gale P A | 2001 | Angew Chem Int Ed Engl2001，40，： | 1 |
| 7 | Antioxidant enzyme activities and mitoehondrial fatty acids in pulmonary hyperten sion syndrome (PHS) in broilers显示文摘 | Iqbal M Cawthon D Beers K | 2002 | Pouh Sci2002，81，2： | 1 |
| 8 | Dimethylthiourea reduces ischemia brain edema without affecting cerebral blood flow 显示文摘 | Martz D Beer M Betz AL | 1990 | Cereb Blood Flow Metab1990，，10： | 1 |
| 9 | Diethylstilbestrol and docetaxel:a PhaseⅡ study of tubulin active agents in patents with metastatic,androgen-independent prostate cancer显示文摘 | Montgomery RB Nelson PS lin D Ryan CW Garzotto M Beer TM | 2007 | Cancer2007，110，5： | 1 |
| 10 | Antioxidant activity ofSouth African red and white cultivar wines:free radical scavenging显示文摘 | de BEER D JUBERT E WENTZEL C A | 2003 | Journal of Agricultural and Food Chemistry2003，51，： | 1 |
| 11 | An investigation into the influence of longitudinal creepage on railway squeal noise due to lateral creepage显示文摘 | Monk-Steel A D Thompson D J De Beer F G | 2006 | Journal of Sound and Vibration2006，293，35： | 1 |
| 12 | Successful knowle dgemanagement projects显示文摘 | DAVENPORT T DE L D BEERS M | 1998 | Sloan Management Review1998，39，2： | 1 |
| 13 | Manganese oxidation by microbial consortia from sand filters显示文摘 | VANDENABEELE J DE BEER D | 1992 | Microb Eco11992，24，： | 1 |
| 14 | Advances in three dimensional printing-state of the art and future Perspectives 显示文摘 | DIMITROV D SEHREVE K DE BEER N | 2006 | Rapid prototyping Journal2006，12，3： | 1 |
| 15 | Quantita- tive real-time PCR assay for determining transgene copy number in transformed plants显示文摘 | INGHAM D J BEER S MONEY S | 2001 | Biotechniques2001，31，1： | 1 |
| 16 | A regional synergy approach to en- ergy recovery: the case of the Kwinana industrial area, Western Australia 显示文摘 | Beers D Biswas W K | 2008 | Energy Conversion and Manage- ment2008，49，： | 1 |
| 17 | Influence of grain size on hot working stresses and microstructures in Mg-3Al-1Zn 显示文摘 | BARNETT M R BEER A G ATWELL D OUDIN A | 2004 | Scripta Mater2004，51，1： | 1 |
| 18 | Microelectrode measurements of the activity distribution in nitrifying bacterial aggregates显示文摘 | BEER D HEUVEL J C OTTENGRAF S P P | 1993 | Applied and Environmental Microbiology1993，59，2： | 1 |
| 19 | Shade management in cof fee and cacao plantations显示文摘 | Beer J Muschler R Kass D | 1998 | Agroforestry Systems1998，38，： | 1 |
| 20 | Liquid flow in heterogeneous biofilms显示文摘 | Beer D Stoodley P Lewandowski Z | 1994 | Biotechnol Bioeng1994，44，5： | 1 |
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