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| 1 | Effects of estrogen replacement therapy on apoptosis and vascular endothelial growth factor expression in ocular surface epithelial cells:An experimental study显示文摘AIM:To investigate the effects of estrogen replacement therapy (ERT) on apoptosis and vascular endothelial growth factor (VEGF) expression in ocular surface in an experimental rat model.· METHODS:Forty female,Wistar rats were randomized in 4 groups in the study.Subcutaneous ERT (17β-estradiol,10g/kg/day) was administered to the first group without ovariectomy and to the second group with ovariectomy for three months.Third group had only ovariectomy and fourth group had sham operation.All rats were sacrificed in estrous cycles determined by vaginal smear test and their right eyes were enucleated at the end of the third month.Enucleated eyes were analyzed by immunohistochemical method for expressions of caspase-3,bcl-2,VEGF and TUNEL assay.· RESULTS:Caspase-3 expression of conjunctival epithelium was significantly higher in group 3 than group 1 (P =0.005),and group 2 (P =0.007).TUNEL score of conjunctival epithelium was significantly higher in group 3 than group 1 (P =0.006).TUNEL score of corneal epithelium was significantly higher in group 3 than group 2 (P =0.012),and group 4 (P =0.002).There was no significant difference between groups in that bcl-2 and VEGF expressions.· CONCLUSION:We determined increased apoptosis in ocular surface epithelial cells in ovariectomized rats.ERT and endogen estrogen decreased the apoptosis,and did not result in difference in VEGF expression between the groups.Estrogen may be beneficial for the treatment of apoptosis-mediated ocular surface disorders such as dry eye.Further studies are needed on this subject for a better understanding of the role of estrogen and to provide a new insight for treatment and prevention of apoptosis-mediated ocular surface disorders. | Fatih zcura Sema Oru Dndar Emel Dikicioglu etin Nahit Beder Mehmet Dndar | 2012 | International Journal of Ophthalmology(English edition)2012，5，1： | 7 |
| 2 | Zn含量对Al-12Si-3Cu合金强度和磨损性能的影响(英文)显示文摘系统研究Zn含量对重力铸造Al-12Si-3Cu合金强度和磨损性能的影响。通过OM、XRD、SEM、硬度、拉伸、压缩和Charpy冲击测试等手段对合金的显微组织和力学性能进行评价。干滑动磨损测试采用球-盘式摩擦磨损仪。显微镜观察结果显示,基体显微组织含有α(Al)枝晶、针状和粗Si颗粒及CuAl2(θ)相。添加Zn导致合金中α-固溶体的形成和粗Si颗粒含量的增加。随着Zn含量的增加,Al-12Si-3Cu-Zn合金的硬度、屈服强度、抗拉强度、抗压强度、断裂伸长率和冲击韧性均增加;但是,当Zn含量为1.5%~2%时,合金的抗拉强度、抗压强度和伸长率均降低。此外,Al-12Si-3Cu-Zn合金的摩擦因数和体积磨损量随Zn含量的增加而减小。总之,在Al-12Si-3Cu合金中加入Zn可以提高其作为摩擦材料的应用潜力。 | Yasin ALEMDAG Murat BEDER | 2019 | Transactions of Nonferrous Metals Society of China2019，29，12： | 2 |
| 3 | Cardiac pacing in children: a 15 - year experience显示文摘 | BEDER SD HANISCH DG COHEN MH | 1985 | AM Hcart J1985，109，： | 1 |
| 4 | Three-dimensional computed tomography and surgical treatment for Eagle's syndrome 显示文摘 | Beder E Ozgursoy OB Karatayli Ozgursoy S | 2006 | Ear Nose Throat J2006，85，7： | 1 |
| 5 | Ways of improving the comfort properties of textiles composed of acrylic fibers显示文摘 | TSCHEGOLJA A S WEIMAN E J BEDER N M | 1980 | Melliand TextilberichteInternational Textile Reports1980，，9： | 1 |
| 6 | Current diagnosis and transoral surgical treatment of Eagle's syndrome显示文摘 | Beder E Ozgursoy O B Karatayli Ozgursoy S | 2005 | J Oral Maxillofac Surg2005，63，12： | 1 |
| 7 | Functional results of plastipore prostheses formiddle ear ossicular chain reconstruction显示文摘 | Bayazit YN Goksu N Beder L | 1999 | Laryngoscope1999，109，5： | 1 |
| 8 | Diagnostic accuracy of cytokine levels (TNF-alpha,IL-2 and IFN-gamma) in bronchoalveolar lavage fluid of smear-negative pulmonary tuberculosis patients显示文摘 | KUPELI E KARANK D BEDER S | 2008 | Respiration2008，75，1： | 1 |
| 9 | Role of miR-200c/miR-141 in the regulation of epithelial-mesenchymaltransition and migration in head and neck squamous cell carcinoma显示文摘 | Shunji Tamagawa Levent Beder Muneki Hotomi Mehmet Gunduz Kazuya Yata Reidar Grenman Noboru Yamanaka | 2014 | International Journal of Molecular Medicine2014，，4： | 1 |
| 10 | Diagnostic accuracy of cyto- kine levels (TNF-alpha, IL-2 and IFN-gamma) in bronchoalveolar lavage fluid of smear-negative pulmonary tuberculosis patients 显示文摘 | Kupeli E Karank D Beder S | 2008 | Respiration2008，75，1： | 1 |
| 11 | Downregulation of ING3 mRNA expression predicts poor prognosis in head and neck cancer 显示文摘 | Gunduz M Beder LB Gunduz E | 2008 | Cancer Sci2008，99，3： | 1 |
| 12 | Enlargement of the bone component in different parts of compensatorily hypertrophied inferior turbinate显示文摘 | Uzun L Savranlar A Beder LB | 2004 | Am J Rhinol2004，18，6： | 1 |
| 13 | H ypereosinophilic syndrome with pulmonary and cardiac involvement in a patient with asthma 显示文摘 | Karnak D Kayaean O Beder S | 2003 | CMAJ2003，168，： | 1 |
| 14 | Genome-wide analyses on loss of heterozygosity in head and neck squamous cell carcinomas显示文摘 | Gunduz M Ouchida M | 2003 | Lab Invest2003，83，1： | 1 |
| 15 | VaR:Seductive but dangerous显示文摘 | Beder T | 1995 | Financial Analysis Journal1995，，： | 1 |
| 16 | Ways of improving the comfort properties of textiles composed of acrylic fibers显示文摘 | Tschegolja A S Weiman E J Beder N M | 1980 | Melliand Texrtilberichte1980，9，11： | 1 |
| 17 | Genome-wide analyses on loss of heterozygosity in head and neck squamous cell carcinomas显示文摘 | Beder LB Gunduz M Ouchida M | 2003 | Lab Invest2003，83，1： | 1 |
| 18 | Hypereosinosinophilie syn- drome with pulmonary and cardial involvement in a patient with asthma 显示文摘 | Karnak D Kayalan O Beder S | 2003 | CMAJ2003，168，： | 1 |
| 19 | Can the effect of anti-biother apy and anti-inflammatory therapy on serum PSA levels discriminate between benign and malign prostatic pathologies?显示文摘 | Erol H Beder N Caliskan T | 2006 | Urol Int2006，76，1： | 1 |
| 20 | Neuron specific enolase and lung cancer显示文摘 | Karnak D Beder S Kayacan O | 2005 | Am J Clin Oncol2005，28，6： | 1 |
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