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7篇 您的检索式：作者名="Bashmakov A"

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		题名	作者	年代	出处	被引量
	1	Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding proteinlc (SREBP-lc) gene by antagonizing ligand-dependent activation of the LXR显示文摘	Ou J Tu H Shan B Luk A DeBose-Boyd RA Bashmakov Y Goldstein JL Brown MS		0，，11：	1
	2	显示文摘	Gover L V Bashmakov I A Kiebooms R	2001	Advanced Materials2001，13，8：	1
	3	Selforganized formation of low- dimensional network structures starting from a nitrocellulose solution显示文摘	Gover L V Bashmakov I A Kaputski F N	2000	Macromol Chem Phys2000，201，：	1
	4	Modulating proxi- mal cell signaling by targeting Btk ameliorates humoral autoim- munity and end-organ disease in murine lupus 显示文摘	Hutcheson J Vanarsa K Bashmakov A	2012	Arthritis Res Ther2012，14，6：	1
	5	Self-organized networks based on conjugated poly- mers 显示文摘	GOVOR L V BASHMAKOV I A KIEBOOMS R	2001	Advanced Materials2001，13，8：	1
	6	Preparation and electrical characterization of low-dimensional net structures made out of GaAs epitaxial layers 显示文摘	GOVOR L V GOLDBACH M BASHMAKOV I A	1999	Phys Lett A1999，261，3：	1
	7	ApoB-containing lipoproteins promote infectivity of chlamydial species in human hepatoma cell line显示文摘AIM:To evaluate the direct binding of two main chlamydial biovars(C.trachomatis and C.pneumoniae) to plasma lipoproteins and its effect on chlamydial infection rate in human hepatoma cell line(HepG2 cells). METHODS:Murine plasma lipoproteins were fractionated and isolated using fast-performance liquid chromatography(FPLC),spotted on nitrocellulose membrane and incubated with chlamydial suspensions. Direct binding of chlamydial particles to lipoprotein fractions has been studied using lipopolysaccharide-specific antibodies in immuno-dot blot binding assay and immunoprecipitation analysis.Immunostaining protocol as well as flow cytometry analysis have been employed to study the infectivity rate of chlamydial species in HepG2 cells. RESULTS:Elementary bodies of both C.trachomatis and C.pneumoniae bind ApoB-containing fractions of plasma lipoproteins.That binding becomes stronger when heat-denatured FPLC fractions are used, suggesting a primary role of apolipoproteins in interaction between chlamydial particle and lipoprotein. Both chlamydial biovars efficiently propagate in human hepatoma cell line-HepG2 cells even in serum free conditions forming late-stage inclusion bodies and releasing extracellular elementary bodies.Preincubation of C.trachomatis and C.pneumoniae with native ApoB-containing lipoproteins enhances the rate of chlamydial infection in HepG2 cells.CONCLUSION:A productive infection caused by C. trachomatis and C.pneumoniae may take place in human-derived hepatocytes revealing hepatic cells as possible target in chlamydial infection.Obtained results may suggest the participation of lipoprotein receptors in the mechanism of attachment and/or entry of chlamydial particles into target cells.	Yuriy K Bashmakov Nailia A Zigangirova Alexander L Gintzburg Petr A Bortsov Ivan M Petyaev	2010	World Journal of Hepatology2010，2，2：	0

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