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| 1 | Proposal of a computed tomography classification for hepatic alveolar echinococcosis显示文摘AIM: To establish a computed tomography(CT)-morphological classification for hepatic alveolar echinococcosis was the aim of the study. METHODS: The CT morphology of hepatic lesions in 228 patients with confirmed alveolar echinococcosis(AE) drawn from the Echinococcus Databank of the University Hospital of Ulm was reviewed retrospectively. For this reason, CT datasets of combined positron emission tomography(PET)-CT examinations were evaluated. The diagnosis of AE was made in patientswith unequivocal seropositivity; positive histological findings following diagnostic puncture or partial resection of the liver; and/or findings typical for AE at either ultrasonography, CT, magnetic resonance imaging or PET-CT. The CT-morphological findings were grouped into the new classification scheme.RESULTS: Within the classification a lesion was dedicated to one out of five 'primary morphologies' as well as to one out of six 'patterns of calcification'. 'primary morphology' and 'pattern of calcification' are primarily focussed on separately from each other and combined, whereas the 'primary morphology' V is not further characterized by a 'pattern of calcification'. Based on the five primary morphologies, further descriptive sub-criteria were appended to types Ⅰ-Ⅲ. An analysis of the calcification pattern in relation to the primary morphology revealed the exclusive association of the central calcification with type Ⅳ primary morphology. Similarly, certain calcification patterns exhibited a clear predominance for other primary morphologies, which underscores the delimitation of the individual primary morphological types from each other. These relationships in terms of calcification patterns extend into the primary morphological sub-criteria, demonstrating the clear subordination of those criteria.CONCLUSION: The proposed CT-morphological classification(EMUC-CT) is intended to facilitate the recognition and interpretation of lesions in hepatic alveolar echinococcosis. This could help to interpret different clinical courses better and shall assist in the context of scientific studies to improve the comparability of CT findings. | Tilmann Graeter Wolfgang Kratzer Suemeyra Oeztuerk Mark Martin Haenle Richard Andrew Mason Andreas Hillenbrand Thomas Kull Thomas F Barth Peter Kern Beate Gruener | 2016 | World Journal of Gastroenterology2016，22，13： | 10 |
| 2 | 通过业余时间运动的中老年的运动心电图:100次运动试验足以确定一个无症状心肌缺血的心脏事件风险显示文摘运动心电图在预防运动员心脏事件方面的重要性一直存在争议。为了确定运动心电图中无症状心肌缺血(silent myocardial ischemia,SMI)的频率及运动心电图与冠状动脉造影评估结果和潜在可预防的心脏事件的关系。Hupin等纳入2011-2014年就诊于Saint-Etienne大学医院运动医学科年龄≥35岁的无症状业余运动员,进行前瞻性队列研究。 | 刘青 叶鹏 Hupin D Edouard P Oriol M Laukkanen J Abraham P Doutreleau S Guy JM CarréF Barthélémy JC Roche F Chatard JC | 2018 | 中华高血压杂志2018，26，4： | 6 |
| 3 | Neutralizing antibodies in hepatitis C virus infection显示文摘Hepatitis C virus (HCV) is a major cause of hepatitis world-wide. The majority of infected individuals develop chronic hepatitis which can then progress to liver cirrhosis and hepatocellular carcinoma. Spontaneous viral clearance occurs in about 20%-30% of acutely infected individuals and results in resolution of infection without sequaelae. Both viral and host factors appear to play an important role for resolution of acute infection. A large body of evidence suggests that a strong, multispecific and long-lasting cellular immune response appears to be important for control of viral infection in acute hepatitis C. Due too the lack of convenient neutralization assays, the impact of neutralizing responses for control of viral infection had been less defined. In recent years, the development of robust tissue culture model systems for HCV entry and infection has finally allowed study of antibody-mediated neutralization and to gain further insights into viral targets of host neutralizing responses. In addition, detailed analysis of antibody-mediated neutralization in individual patients as well as cohorts with well defined viral isolates has enabled the study of neutralizing responses in the course of HCV infection and characterization of the impact of neutralizing antibodiesfor control of viral infection. This review will summarize recent progress in the understanding of the molecular mechanisms of antibody-mediated neutralization and its impact for HCV pathogenesis. | Mirjam B Zeisel Samira Fafi-Kremer Isabel Fofana Heidi Barth Franoise Stoll-Keller Michel Doffo■l Thomas F Baumert | 2007 | World Journal of Gastroenterology2007，13，36： | 3 |
| 4 | The water framework directive and European water policy显示文摘 | Barth F Fawell J | 2001 | Ecotoxicology and Environmental Safety2001，50，： | 2 |
| 5 | Cellular antitumor immune response to a branched lysine multiple antigenic peptide containing epitopes of a common tumor-specific antigen in a rat glioma model 显示文摘 | M J Ciesielski A L Kazim R F Barth | 2005 | Cancer Immunol Immunother2005，54，2： | 1 |
| 6 | The clinical and topographic spectrum of cerebellar infarcts: a clinical magnetic resonance imaging correlation study显示文摘 | Barth A Bogousslavsky J Regli F | 1993 | Ann Neurol1993，33，： | 1 |
| 7 | Intratumoral de-livery of boronated epidermal growth factor for neutron cap-ture therapy of brain tumors显示文摘 | Yang W Barth R F Adams D M | 1997 | Carcer Res1997，57，19： | 1 |
| 8 | Tracking the budget of Nb and Ta in the continental crust显示文摘 | Barth M G McDonough W F Rudnick R L | 2000 | Chemical Ge- ology2000，165，34： | 1 |
| 9 | Boron neutron capture therapy of brain tumors:Past history,current status,and future potential显示文摘 | BARTH R F SOLOWAY A H BRUGGER R M | 1996 | Cancer Invest1996，14，6： | 1 |
| 10 | Synthesisand applications of one-dimensional semiconductors显示文摘 | BARTH S RAMIREZ F H HOLMES J D | 2010 | Progressin Materials Science2010，55，6： | 1 |
| 11 | The Clinical and Topographic Spectrum of Cerebellar Infarcts:a Clinical-Magnetic Resonance Imaging Correlation Study 显示文摘 | Barth A Bogousslavsky J Rei F | 1993 | Ann Neurol ( S0364 - 5134 )1993，33，： | 1 |
| 12 | A new method of 3-D cephalometry Part I: the anatomic Cartesian 3-D reference system 显示文摘 | Swennen GR Schutyser F Barth EL | 2006 | J Craniofac Surg2006，17，2： | 1 |
| 13 | Data pro- cessing algorithms used by NOAA's wind p~ofiler demonstra- tion network显示文摘 | Barth M F Chadwick R B van de Kamp D W | 1994 | Annales Geophysicae1994，12，6： | 1 |
| 14 | Oscillatory interlayer exchange and magnetoresistance in Fe/Cu multilayers显示文摘 | PETROFF F BARTH(E)LEMY A MOSCA D H | 1991 | Phys Rev B1991，44，10： | 1 |
| 15 | Spinel Structures with and without Variate Atom Equipoints 显示文摘 | Barth T F W Posnjak E | 1932 | Z Kristallogr Kristallgeom Kristallphys Kristallchem1932，82，56： | 1 |
| 16 | An evaluation of two automated quality control methods designed for use with hourly wind profiler data显示文摘 | MILLER P A BARTH M F van de KAMP D W | 1994 | Ann Geophysieae1994，12，8： | 1 |
| 17 | Silicon displacement threshold energy determined by electron paramagnetic resonance and positron annihilation spectroscopy in cubic and hexagonal poly types of silicon carbide显示文摘 | Kerbiriou X Barthe M F Esnouf S | 2007 | J Nucl Mater2007，362，3： | 1 |
| 18 | Start-up of autotrophic nitrogen removal reactors via sequential biocatalyst addition 显示文摘 | Pynaert K Barth F beheydt D | 2004 | Environmental Science and Technology2004，38，4： | 1 |
| 19 | Autophagy: assays and arti- facts显示文摘 | Barth S Glick D Macleod K F | 2010 | J Pathol2010，221，2： | 1 |
| 20 | Population Pharmaeokineties and its Role in Anti-tuberculosis Drug Development & Optimization of Treatment 显示文摘 | Egelund E F Barth A B Peloquin C A | 2011 | Curr Pharm Des2011，17，27： | 1 |
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