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18篇 您的检索式:作者名="Barrie KA"
    题名 作者 年代 出处 被引量
1Internal fixation for intraarticular distal radius fractures显示文摘Barrie KA Wolfe SW 2002Tech Hand Up Extrem Surg2002,6,1:1
2Dimethyl methylphosphonate(DMMP):a 31P nuclear magnetic reoonailce spectroscopic probe of intracellular volume in mammalian cell cultures显示文摘 McGovern KA Lien YH 1993Biochemistry1993,32,17:1
3Internal fixation for intraartieular distal ra- dius fractures显示文摘Barrie KA Wolfe SW 2002Tech Hand Up Extren Surg2002,6,:1
4Gracilis freemuscle transfer for restoration of function after complete bra-chial plexus avulsion显示文摘Barrie KA Steinmann SP Shin AY 2004Neurosurg Focus2004,16,5:1
5Internal fixation for intraartieular distal radius fractures 显示文摘Barrie KA Wolfe SW 2002Tech Hand UP Extren Surg2002,6,1:1
6Results of nerve transfer techniques for restoration of shoulder and elbow function in the context of a meta-analysis of the English literature显示文摘Merrell GA Barrie KA Katz DL 2001J Hand Surg Am2001,26,2:1
7The role of eosinophih in the pathogenesis of asthma显示文摘Barry KA 2005Trends in Molecular Medicine2005,11,4:1
8Internal fixation for intraarticular distal radius fractures显示文摘Barrie KA Wolfe SW 0,,06:1
9Inappropriate prescribing in the elderly:a comparison of the Beers Criteria and the Improved Prescribing in the Elderly Tool (IPET) in acutely ill elderly hospitalized patients显示文摘Barry PJ O'Keefe N O'Connor KA 2006J Clin Pharm Ther2006,31,6:1
10Impaired conflict resolu- tion and alerting in children with ADHD: Evidence from the Atten- tion Network Task (ANT) 显示文摘Johnson KA Robertson IH Barry E 2008J Child Psychol Psychiatry2008,49,12:1
11Spatial attentional biasas amarker of genetic risk, symptom severity, and stimulant re- sponse in ADHD 显示文摘Bellgrove MA Barry E Johnson KA 2008Neuropsychopharmacology2008,33,10:1
12Separation and properties of cellular and scrapie prion proteins 显示文摘Meyer RK McKinley MP Bowman KA Braunfeld MB Barry RA Prusiner S8 1986Proc Natl Acad Sci USA1986,83,8:1
13The role of eosinophils in the pathogenesis of asthma显示文摘Barry KA 2005Trends in Molecular Medicine2005,11,4:1
14Results of nerve transfer techniques for restoration of shoulder and elbow function in the context of a mm - analysis of the English literature 显示文摘Merrell GA Barrie KA Katz DL 2001J Hand Surg ( Am )2001,26,:1
15Inappropriate prescribing in the elderly: a comparison of the Beers criteria and the improved prescribing in theelderly tool(IPET) in acutely ill elderly hospitalized patients显示文摘Barry P J O'Keefe N O'Connor KA 2006J Clin Pharm Ther2006,31,6:1
16The role of multiple strands and locking sutures on gap formation of flexor tendon repairs during cyclical loading 显示文摘Barrie KA Tomak SL Cholewicki J 2000Hand Surg America2000,25,:1
17Internal fixation for intraarticular distal radius fractures显示文摘Barrie KA Wolfe SW 2002Tech Hand Up Extren Surg2002,6,:1
18Effect of herpesvirus infection on pancreatic duct cell secretion显示文摘AIM: To examine the effect of acute infection caused by herpesvirus (pseudorabies virus, PRV) on pancreatic ductal secretion.METHODS: The virulent Ba-DupGreen (BDG) and nonvirulent Ka-RREpOlacgfp (KEG) genetically modified strains of PRV were used in this study and both of them contain the gene for green fluorescent protein (GFP). Small intra/interlobular ducts were infected with BDG virus (107 PFU/mL for 6 h) or with KEG virus (1010 PFU/mL for 6 h), while non-infected ducts were incubated only with the culture media. The ducts were then cultured for a further 18 h.The rate of HCO3- secretion [base efflux -J(B-)] was determined from the buffering capacity of the cells and the initial rate of intracellular acidification (1) after sudden blockage of basolateral base loaders with dihydro-4,4,-diisothiocyanatostilbene-2,2,-disulfonic acid (500 μmol/L)and amiloride (200 μmol/L), and (2) after alkali loading the ducts by exposure to NH4Cl. All the experiments were performed in HCO3--buffered Ringer solution at 37 ℃ (n = 5ducts for each experimental condition). Viral structural proteins were visualized by immunohistochemistry. Virallyencoded GFP and immunofluorescence signals were recorded by a confocal laser scanning microscope.RESULTS: The BDG virus infected the majority of accessible cells of the duct as judged by the appearance of GFP and viral antigens in the ductal cells. KEG virus caused a similarly high efficiency of infection. After blockage of basolateral base loaders, BDG infection significantly elevated -J(B-) 24 h after the infection, compared to the non-infected group. However, KEG infection did not modify -J(B-). After alkali loading the ducts, -J(B-) was significantly elevated in the BDG group compared to the control group 24 h after the infection. As we found with the inhibitor stop method, no change was observed in the group KEG compared to the non-infected group.CONCLUSION: Incubation with the BDG or KEG strains of PRV results in an effective infection of ductal epithelial cells. The BDG strain of PRV, which is able to initiate a lytic viral cycle, stimulates HcO3- secretion in guinea pig pancreatic duct by about four- to fivefold, 24 h after the infection. However, the KEG strain of PRV, which can infect,but fails to replicate, has no effect on HCO3- secretion.We suggest that this response of pancreatic ducts to virulent PRV infection may represent a defense mechanism against invasive pathogens to avoid pancreatic injury.Péter Hegyi Balázs rdg Zoltán Rakonczai Jr Tamás Takács János Lonovics Annamária Szabolcs Réka Sári András Tóth Julius G Papp András Varró Mária K Kovács Mike A Gray Barry E Argent Zsolt Boldogki 2005World Journal of Gastroenterology2005,11,38:0
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