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35篇 您的检索式：作者名="Barnoud"

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	题名	作者	年代	出处	被引量
1	Common genetic variants in the TP53 pathway and their impact on cancer显示文摘The TP53 gene is well known to be the most frequently mutated gene in human cancer.In addition to mutations,there are > 20 different coding region single-nucleotide polymorphisms (SNPs) in the TP53 gene,as well as SNPs in MDM2,the negative regulator of p53.Several of these SNPs are known to alter p53 pathway function.This makes p53 rather unique among cancer-critical genes,e.g.the coding regions of other cancer-critical genes like Ha-Ras,RB,and PI3KCA do not have non-synonymous coding region SNPs that alter their function in cancer.The next frontier in p53 biology will consist of probing which of these coding region SNPs are moderately or strongly pathogenic and whether they influence cancer risk and the efficacy of cancer therapy.The challenge after that will consist of determining whether we can tailor chemotherapy to correct the defects for each ofthese variants.Here we review the SNPs in TP53 and MDM2 that show the most significant impact on cancer and other diseases.We also propose avenues for how this information can be used to better inform personalized medicine approaches to cancer and other diseases.	Thibaut Barnoud Joshua L.D.Parris Maureen E.Murphy	2019	Journal of Molecular Cell Biology2019，11，7：	7
2	Prevalence and consequences of nutritional depletion in lung transplant candidates显示文摘	Schwebel C Pin I Barnoud D	2000	Eur Respir2000，16，：	1
3	The Lauren classification highlights the role of epithelial-to-mesenchymal transition in gastric carcinogenesis:an immunohistochemistry study of the STAT3and adhesion molecules expression显示文摘	Susman S Barnoud R Bibeau F	2015	J Gastrointestin Liver Dis2015，24，1：	1
4	The effectiveness of trastuzumab (Herceptin) combined with chemotherapy for gastric carcinoma with overexpression of the c-erbB-2 protein显示文摘	Rebischung C Barnoud R Stefani L	2005	Gastric Cancer2005，8，4：	1
5	The effectiveness of trastuzumab (Herceptin) combined with chemotherapy for gastric carcinoma with overexpression of the c-erbB-2 protein 显示文摘	Rebisc hung C Barnoud R Stefani L	2005	Gastric Cancer2005，8，4：	1
6	The effective- ness of trastuzumab (Herceptin) combined with chemotherapy for gastric carcinoma with overexpression of the C-erbB-2 protein 显示文摘	Rebischung C Barnoud R Stefani L	2005	Gastric Cancer2005，8，4：	1
7	Sclerosing polycystic ade-nosis of the parotid gland:diagnosis and management显示文摘	Perottino F Barnoud R Ambrun A	2010	Eur Ann Otorhinolaryngol Head Neck Dis2010，127，1：	1
8	The effectiveness of trastuzumab (Herceptin) combined with chemotherapy for gastric carcinoma with overexpression of the c-erbB-2 protein 显示文摘	Rebischung C Barnoud R Stefani L	2005	Gastric Cancer2005，8，4：	1
9	Immunohistochemical expression of WT1 by desmoplastic small round cell tumor: a comparative study with other small round cell tumors显示文摘	Barnoud R Sabourin JC Pasquier D	2000	Am J Surg Pathol2000，24，6：	1
10	Desmoplastic small round cell tumor:RT-PCR analysis and immunohistochemical detection of the Wilm's tumor gene WT1显示文摘	Barnoud R Delattre O Peoc'h M	1998	Pathol Res Pract1998，194，10：	1
11	Prevalence and consequences of nutritional depletion in lung transplant candidates 显示文摘	Schwebel C Pin I Barnoud D	2000	Eur Respir J2000，16，6：	1
12	A pancreatic metastasis from a colon cancer显示文摘	A. Stoltz R. Barnoud V. Plok C. Ducerf J. Baulieux J.-Y. Mabrut	2011	Clinics and Research in Hepatology and Gastroenterology2011，，8：	1
13	The effective- ness of trastuzumab(Herceptin) combined with chemother- apy for gastric carcinoma with over expression of the c- erbB-2 protein显示文摘	Rebischunge C Barnoud R Stefani L	2005	Gastric Cancer2005，8，4：	1
14	Sclerosing polycystic adenosis of the paretid gland : diagnosis and management 显示文摘	Perottino F Barnoud R Ambrun A	2010	Eur Ann Otorhinolaryngol Head Neck Dis2010，127，1：	1
15	Lipid membranes as solvents for carbon nanoparticles 显示文摘	Barnoud J Rossi G Monticelli L	2014	Physical Review Letters2014，112，06：	1
16	The effective- ness of trastuzumab (Herceptin) combined with chem- otherapy for gastric carcinoma with overexpression of the c - erbB - 2 protein 显示文摘	Rebischung C Barnoud R Stefani L	2005	Gastric Cancer2005，8，4：	1
17	Stress metabolism and nutritional support in acute renal failure显示文摘	Leverve X Barnoud D		0，，66：	1
18	Chemical and 13C-NMR studies on two arabinans from the inner bark of young stems of Rosa glauca显示文摘	Joseleau J.-P Chambat G Vignon M Barnoud F		0，，：	1
19	The effectiveness of trastuzumab (Herceptin) combined with chemotherapy for gastric carcinoma with overexpreasion of the c-erhB-2 protein显示文摘	Rebischung C Barnoud R Stefani L	2005	GastricCancer2005，8，4：	1
20	Synovial sarcoma of the lateral pharyngeal wall显示文摘	C. Daveau G. Buiret M. Poupart R. Barnoud J.-C. Pignat	2012	European Annals of Otorhinolaryngology Head and Neck diseases2012，，6：	1

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