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| 1 | Transformation of wheat with high molecular weight subunit genes results in improved functional properties显示文摘 | Barro F Rooke L Bekes F Gras P Tatham A S Fido R Lazzeri P A Shewry P R Barcelo P | 1997 | Nat Biotechnol1997，15，12： | 2 |
| 2 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 3 | Trimeric autotransporters of Haemo philus parasuis , generation of an extensive passenger domain repertoire specific for pathogenic strains显示文摘 | Pina S Olvera A BarcelO A | 2009 | BacteriolJ2009，191，： | 1 |
| 4 | Hydrogen peroxide production is a general property of the lignifying xylem from vascular plants 显示文摘 | Rao Barcelo A | 1998 | Ann Bot1998，82，： | 1 |
| 5 | Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry显示文摘 | JELIC A PETROVIC M BARCELO D | 2009 | Talanta2009，80，1： | 1 |
| 6 | Biweekly administration of eisplatin/gemcitabine in advanced nonsmall cell lung cancer 显示文摘 | Lopez-Vivanco G Viteri A Barcelo R | 2005 | Am J Clin Oncol2005，28，5： | 1 |
| 7 | Can the maturity concept be used to separate the autogenous shrinkage and thermal deformation of a cement paste at early age?显示文摘 | TURCRY P LOUKILI A BARCELO L | 2002 | Cement and Concrete Research2002，32，9： | 1 |
| 8 | Field evaluation and agronomic performance of transgenic wheat显示文摘 | BARRO F BARCELO P LAZZERI P A | 2002 | Theor Appl Genet2002，105，： | 1 |
| 9 | Trimric autotransporters of Haemophilus parasuis:generation of an extensive passenger domain repertoire secific for pathogenic strains显示文摘 | Pina S Olvera A Barcelo A | 2009 | J Bacteriol2009，191，2： | 1 |
| 10 | Potential chlorinated and brominated interferences on the polybrominated diphenyl ether determinations by gas chromatography-mass spectrometry显示文摘 | ELJARRAT E de LA CAL A BARCELO D | 2003 | J Chromatogr A2003，1008，： | 1 |
| 11 | Peptide YY, gluca gon-like peptide-1, and neurotensin responses to luminal factors in the isolated vascularly perfused rat ileum显示文摘 | Dumoulin V Moro F Barcelo A | 1998 | Endocrinology1998，139，9： | 1 |
| 12 | Assessment of Priority Pesticides, Degradation Products, and Pesticide Adjuvants in Groundwaters and Top Soils From Agricultural Areas of the Ebro River Basin 显示文摘 | Hildebrandt A Lacorte S Barcelo D | 2007 | Anal Bioanal Chem2007，387，4： | 1 |
| 13 | Heat flow and related minimization problem in image restoration显示文摘 | Barcelos C A Z Chen Y | 2000 | Computers and Mathematics with Applications2000，39，： | 1 |
| 14 | Aluminum tolerance of maize cultivars as assessed by callose production and root elongation 显示文摘 | Llugany M Massot N Wissemeier A H Poschenrieder C Horst W J Barcelo' J | 1994 | J Plant Nutr Soil Sci1994，157，： | 1 |
| 15 | Determination of nonylphenol an octylphenol in paper by microwave-assisted extraction coupled to headspace solidphase microextraction and gas chromatography-mass spectrometry 显示文摘 | LATORRE A LACORTE S BARCELO D | 2005 | J Chromatogr A2005，1065，： | 1 |
| 16 | Biweekly administration of cisplatin/gemcitabine in advanced nonsmall cell lung cancer显示文摘 | Lopez-Vivanco G Viteri A Barcelo R | 2005 | Am J Clin Oncol2005，28，5： | 1 |
| 17 | Automated trace determination of earthy-musty odorous compounds in water samples by on-line purge-and-trap-gas chromatography-mass spectrometry显示文摘 | SALEMI A LACORTE S BAGHERI H BARCELO D | 2006 | Journal of Chromatography A2006，1136，2： | 1 |
| 18 | Camparative degradation kinetics of alachlor in water by photocatalysis with FeCl3 , TiO2 and photolysis,studied by solid phase disk extraction followed by gas chromatographic techniques显示文摘 | Penuela G A Barcelo D 1996 | 1996 | J Chrom1996，754，： | 1 |
| 19 | Chemotherapy for bladder cancer显示文摘 | MUNOZ A BARCELO J R LOPEZ-VIVANCO G | 2003 | N Engl J Med2003，349，23： | 1 |
| 20 | Adhesion properties and stabi- lity of polyurethane adhesive to synthetic rubber joints显示文摘 | MARTIN-MARTINEZ J M FERNANDEZ GARCIA J C ORGILES BARCELO A C | 1991 | International Journal of Adhesion and Adhesives1991，11，3： | 1 |
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