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| 1 | Transformation of wheat with high molecular weight subunit genes results in improved functional properties显示文摘 | Barro F Rooke L Bekes F Gras P Tatham A S Fido R Lazzeri P A Shewry P R Barcelo P | 1997 | Nat Biotechnol1997，15，12： | 2 |
| 2 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 3 | Trace ele- ment behaviour at the root-soil interface: Implications in phytoremediation显示文摘 | KIDD P BARCELO J BERNAL M P | 2009 | Eviron Exp Bot2009，67，： | 1 |
| 4 | Dietary carotenoid lutein protects against DNA damage and alterations of the redox status induced by cisplatin in human derived HepG2 cells显示文摘 | Serpeloni J M Barcelos G R Friedmann Angeli J P | 2012 | Toxicology in Vitro2012，26，2： | 1 |
| 5 | Can the maturity concept be used to separate the autogenous shrinkage and thermal deformation of a cement paste at early age?显示文摘 | TURCRY P LOUKILI A BARCELO L | 2002 | Cement and Concrete Research2002，32，9： | 1 |
| 6 | Field evaluation and agronomic performance of transgenic wheat显示文摘 | BARRO F BARCELO P LAZZERI P A | 2002 | Theor Appl Genet2002，105，： | 1 |
| 7 | Simuhaneous determination of hexabromocyclododecane, tetrabromobisphenol A, and related compounds in sewage sludge and sediment samples from Ebro River basin (Spain) 显示文摘 | Guerra P Eljarrat E Barcelo D | 2010 | Anal Bioanal Chem2010，397，7： | 1 |
| 8 | Transgene inheritance,segregation and expression in bread wheat显示文摘 | Leonie R Steele S H Barcelo P | 2003 | Euphytica2003，129，： | 1 |
| 9 | Effects of dipyridamole,soluflazine and related molecules on adnosine uptake and metabolism by isolated human red blood cells显示文摘 | Barcelo B Perche JC | 1995 | Fundom Clin Pharmacol1995，9，： | 1 |
| 10 | Can the maturity concept be used to separate the autogenous shrinkage and the thermal deformation of a cement paste at early age? 显示文摘 | P Turcry A Loukili L Barcelo J M Casabonne | 2002 | Cement and Concrete Research2002，，32： | 1 |
| 11 | Comparative analysis of the spindle and chromosome configurations of in vitro-matured oocytes from patients with endometriosis and from control subjects: a pilot study显示文摘 | BARCELOS I D VIEIRA R C FERREIRA E M MARTINS W P FERRIANI R A NAVARRO P A | 2009 | Fertil Steril2009，92，： | 1 |
| 12 | Dynamic economic dispatch using the extended security constrained economic dispatch algorithm 显示文摘 | Barcelo W R Rastgoufard P | 1997 | IEEE Trans on Power Systems1997，12，2： | 1 |
| 13 | Transgenic cereal ( tritordeum) Plant obtained at high efficiency by microprojectile bombardment of inflorescence tissue显示文摘 | Barcelo P Hagel C Becker D | 1994 | Plant J1994，5，： | 1 |
| 14 | Effects of Dipyridamole, soluflazine and related molecules on adnosineuptake and metabolism by isolated human red blood cells显示文摘 | Ferrandon P Barcelo B Perche JC | 1995 | Fundom Clin Pharmacol1995，9，2： | 1 |
| 15 | Regenerative response of hepatocytes implanted in the spleen显示文摘 | GARCIA-ALONSO I BARCELO P PORTUGAL V | 1991 | Rev Esp Enferm Dig1991，80，4： | 1 |
| 16 | Phosphoinositide 3-ki- nase gamma gene knockout impairs postischemie neovasculariza- tion and endothelial progenitor cell functions 显示文摘 | Madeddu P Kraenkel N Barcelos LS | 2008 | Arterioscler Thromb Vasc Biol2008，28，1： | 1 |
| 17 | Transgenic cereal ( tritordeum) Plant obtained at high efficiency by microprojectile bombardment of inflorescence tissue显示文摘 | Barcelo P Hagel C Becker D | 1994 | Plant J1994，5，： | 1 |
| 18 | Effects of cyclosporine A on Na+-K+- ATPase expression in the renal epithelial cell line NBL - 1 显示文摘 | Ferrer - Martinez A Felipe A Barcelo P | 1996 | Kidney Int1996，50，5： | 1 |
| 19 | Enantiomerie specific determination of hexabromoeyelododecane by liquid chromatography- quadrupole linear ion trap mass speetremetry in sediment samples显示文摘 | GUERRA P ELJARRAT E BARCELO D | 2008 | Journal of Chromatography A2008，1203，1： | 1 |
| 20 | Simultaneous determination of hexabromocyclododecane, tetrabromobisphenol A, and related compounds in sewage sludge and sediment samples from Ebro River Basin (Spain) 显示文摘 | GUERRA P ELJARRAT E BARCELO D | 2010 | Analytical and Bioanalytieal Chemistry2010，397，7： | 1 |
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