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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Effect of sodium replacement on the quality characteristics of pastırma(a dry-cured meat product)显示文摘This study aims to investigate the effect of sodium replacement on the quality characteristics of pastırma.For this purpose,pastırma production with four different salt mixtures(Ⅰ.100%NaCl;Ⅱ.50%NaCl+50%KCl;Ⅲ.40%NaCl+40%KCl+20%CaCl_(2);Ⅳ.30%NaCl+40%KCl+20%CaCl_(2)+10%MgCl_(2))were carried out using traditional method.The use of different salt mixtures for pastırma had no statistically significant effect on the microbial counts and residual nitrite of the final product.The a*and b*values were affected by this treatment.The salt mixture containing CaCl_(2) or CaCl_(2)+MgCl_(2) significantly decreased the pH values and sensory scores.The eighteen volatile compounds were affected by the salt mixtures.Na^(+),K^(+),Ca^(2+),and Mg^(2+)had a certain increase depending on their ratio in the salt mixtures.The highest Cathepsin activity in all pastırma samples was observed in Cathepsin B+L.The salt mixture with NaCl+KCl+CaCl_(2)+MgCl_(2) increased acid lipase activity.However,this mixture had no significant effect on neutral lipase activity. | BarışYalınkılıç Güzin Kaban Mükerrem Kaya | 2023 | Food Science and Human Wellness2023，12，1： | 2 |
| 3 | Efficacy,tolerability,and effects on quality of life of losartan,alone or with hydrochlorothiazide,in patients with essential hypertension显示文摘 | Bar E Elkins M | 1996 | Clin Ther1996，18，： | 1 |
| 4 | Refining vegetation simulation models: From plant functional types to bioclimatic affinity groups of plants 显示文摘 | Laurent J M Bar - Hen A Fran ois L | 2004 | Journal of Vegetation Science2004，15，： | 1 |
| 5 | Tolerability and safety of peram-panel :two randomized dose-escalation studies 显示文摘 | Krauss GL Bar M Biton V | 2012 | Acta NeurolScand2012，125，1： | 1 |
| 6 | Inflammatory markers predict late cardiac events in patients who are exhausted after percu- taneous coronary intervention 显示文摘 | Kwaijtaal M van Diest R Bar FW | 2005 | Atherosclerosis2005，182，2： | 1 |
| 7 | A proposed scheme for viroid classification and nomenclature 显示文摘 | Flores R Randles J W Bar Joseph M | 1998 | Arch Virol1998，143，： | 1 |
| 8 | Effects of enoxaparin on late pregnan- cy complications and neonatal outcome in women with recurrent preg- nancy loss and thrembophilia: resultsfrem the Live-Enox study 显示文摘 | Brenner B Bar J Ellis M | 2005 | Fertil Steril2005，84，3： | 1 |
| 9 | Pathology teach and tell: eosinophilic granuloma 显示文摘 | Khalil F K Wallis Crespo M C Gilbert Barness E | 2004 | Fetal Pediatr Pathol2004，23，4： | 1 |
| 10 | Postmortem stability of DNA显示文摘 | Bar W Kratzer A Machler M | 1988 | Forensic Sci Int1988，39，1： | 1 |
| 11 | Cell adhesion: im- plication in tumor progression 显示文摘 | Zigler M Dobroff AS Bar - Eli M | 2010 | Minerva Med2010，101，3： | 1 |
| 12 | Early domesticated fig in the Jordan Valley显示文摘 | Kislev M E Hartmann A Bar Yosef O | 2006 | Science2006，312，： | 1 |
| 13 | Radiation-induced apoptosis 显示文摘 | Verheij M Bar telink H | 2000 | Cell Tissue Res2000，301，1： | 1 |
| 14 | EHD2 inhibits ligand-induced endocytosis and signaling of the leucine-rich repeat receptor-like protein LeEix2 显示文摘 | Bar M Avni A | 2009 | Plant J2009，59，： | 1 |
| 15 | ImmuKnow: a new parameter in immune monitoring of pediatric liver transplantation recipients 显示文摘 | Israeli M Klein T Sredni B Avitzur Y Mor E Bar Nathen N | 2008 | Liver Transpl2008，14，： | 1 |
| 16 | Q-T dispersion and sudden unexpected death in chronic heart failure 显示文摘 | Bar C Nass A Freeman M | 1994 | Lancet1994，343，： | 1 |
| 17 | Spiral break up and defect dynamics in a model for intracellular Ca^2+ dynamics 显示文摘 | Falcke M Bar M Lechleiter J D | 1999 | Physica D1999，129，： | 1 |
| 18 | Postmortem stability of DNA 显示文摘 | Bar W Kratzer A Machler M | 1988 | Forensic Sci Int1988，39，1： | 1 |
| 19 | Identification of failure modes in GFRP using PDVF sensors:ANN approach显示文摘 | H N Bar M R Bhat | 2004 | Composite Structures2004，65，： | 1 |
| 20 | Influence of olanzap- ine on QT variability and complexity measures of heart rate in pa- tients with schizophrenia 显示文摘 | BAR K J KOSCHKE M BERGER S | 2008 | J Clin Psychopharmacol2008，28，6： | 1 |
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