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| 1 | Meta-analysis of the relationship between Epstein-Barr virus infection and clinicopathological features of patients with gastric carcinoma显示文摘Epstein-Barr virus (EBV) infection has been causally associated with occurrence of many malignant neoplasms. EBV-encoded small RNAs (EBERs) have been detected from about 10% of gastric carcinoma tissue cells, suggesting that EBV infection is associated with the development of gastric carcinoma. The present study pooled the data from the papers concerning EBV-related gastric cancers and performed a meta-analysis of 22 research papers. Among these papers, a total of 5475 cases with gastric cancer were enrolled, of whom 411 cases were found EBV-positive, with the EBV-positive rate being 7.5%. Among the EBV-positive gastric cancer cases, the detection rate was 11.1% in males and 3.0% in females. Compared with EBV-negative gastric cancer, EBV-positive gastric cancer had less lymph node metastasis. Based on the histological typing, of the EBV-positive gastric cancers, the diffuse type was 8.1%, and intestinal type was 8.0%. The examined specimen types included stored paraffin blocks and fresh surgically removed specimens, their EBV positive rates were 7.9% and 6.5% respectively. In terms of geographical distribution, the detection rate of EBV-positive gastric cancer was 9.4% in America, 6.1% in Asia and 9.1% in Europe. Meta-analysis showed that EBV infection occurred only in gastric cancer tissue cells and was significantly associated with the patients’ gender, lymph node metastases, and the location where tumor tissue generated and geographical distribution (P<0.05), but was not significantly associated with the patients’ histological types of tumor and the types of specimens (P>0.05). These results suggested that EBV-positive gastric cancer has distinct clinicopathological features. | LI ShuYing1,2, DU HaiJun3, WANG Zhan3, ZHOU Ling3, ZHAO XiaoYu1 & ZENG Yi3 1 College of Life Sciences, Hebei University, Baoding 071002, China 2 Department of Pathogenic Biology, Faculty of Biological Science, North China Coal Medical College, Tangshan 063000, China 3 National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (Chinese CDC), State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing 100052, China | 2010 | Science China(Life Sciences)2010，53，4： | 17 |
| 2 | Study on method and mechanism for simultaneous desulfurization and denitrification of flue gas based on the TiO_2 photocatalysis显示文摘Based on the TiO2 photocatalysis mechanism, a new method of simultaneous desulfurization and denitrification from flue gas was proposed. Preparation of TiO2 photocatalyst, design of photocatalysis reactor and influencing factors for simul- taneous removal of SO2 and NO, and removal mechanism of SO2 and NO were studied. After the optimal values of concentration of O2 in flue gas, the relative humidity of flue gas and the irradiation time in the photocatalysis reactor were used, the efficiencies of removal for SO2 and NO can be achieved above 98% and about 67%, respectively. According to the results of removal products analysis, the re- moval mechanism of SO2 and NO based on TiO2 photocatlysis can be put forward, namely, SO2 was oxidized to SO3 partly, the bulk of NO was oxidized to NO2, and both were removed by resorbing finally. | ZHAO Yi, ZHAO Li, HAN Jing, XU YongYi & WANG ShuQin School of Environmental Science & Engineering, North China Electric Power University, Baoding 071003, China | 2008 | Science China(Technological Sciences)2008，51，3： | 9 |
| 3 | Surface modification of hydrophobic NaYF_4:Yb,Er upconversion nanophosphors and their applications for immunoassay显示文摘β-NaYF4:Yb,Er upconversion nanophosphor (UCNP) is known as one of the most efficient NIR-to-visible upconversion materials, which shows great potential in bioanalytical chemistry and bioimaging. However, its applications are greatly limited due to its low water dispersibility and thus poor biocompatibility. In this paper, poly(acrylic acid) (PAA)-based ligand exchange strategies are carried out to modify oleic acid-capped hydrophobic β-NaYF4:Yb,Er UCNPs into hydrophilic ones. After efficient surface modification, the presence of free carboxylic acid groups on the surfaces of UCNPs results in high solubility in water, and also allows further conjugation with NH2-containing biomolecules. Facilitated by the covalent linkage between the-COOH groups on UCNPs surfaces and -NH2 groups in antigen/antibody, a sensitive immunosensor is constructed by using PAA-functionalized β-NaYF4:Yb,Er UCNPs as biolabels. Through monitoring the upconversion fluorescence intensity or fluorescent imaging of the final immunocomplexes, high sensitivity is achieved for the proposed immunoassay and as low as 0.1 ng/mL goat anti-human immunoglobulin G (IgG) can be detected, which suggests that PAA-modified UCNPs may serve as an ideal candidate for use as bioanalysis and bioimaging probes. | LIU ChengHui, WANG Zhe, WANG XiaoKe & LI ZhengPing Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China | 2011 | Science China Chemistry2011，54，8： | 6 |
| 4 | Real-variable characterizations of anisotropic product Musielak-Orlicz Hardy spaces显示文摘Let A :=(A_1, A_2) be a pair of expansive dilations and φ : R^n×R^m×[0, ∞) → [0, ∞) an anisotropic product Musielak-Orlicz function. In this article, we introduce the anisotropic product Musielak-Orlicz Hardy space H~φ_A(R^n× R^m) via the anisotropic Lusin-area function and establish its atomic characterization, the g-function characterization, the g_λ~*-function characterization and the discrete wavelet characterization via first giving out an anisotropic product Peetre inequality of Musielak-Orlicz type. Moreover, we prove that finite atomic decomposition norm on a dense subspace of H~φ_A(R^n× R^m) is equivalent to the standard infinite atomic decomposition norm. As an application, we show that, for a given admissible triplet(φ, q, s), if T is a sublinear operator and maps all(φ, q, s)-atoms into uniformly bounded elements of some quasi-Banach spaces B, then T uniquely extends to a bounded sublinear operator from H~φ_A(R^n× R^m) to B. Another application is that we obtain the boundedness of anisotropic product singular integral operators from H~φ_A(R^n× R^m) to L~φ(R^n× R^m)and from H~φ_A(R^n×R^m) to itself, whose kernels are adapted to the action of A. The results of this article essentially extend the existing results for weighted product Hardy spaces on R^n× R^m and are new even for classical product Orlicz-Hardy spaces. | FAN XingYa HE JianXun LI BaoDe YANG DaChun | 2017 | Science China Mathematics2017，60，11： | 5 |
| 5 | Epigenetic reprogramming in mammalian nuclear transfer显示文摘Somatic cloning has been succeeded in some species, but the cloning efficiency is very low, which limits the application of the technique in many areas of research and biotechnology. The cloning of mammals by somatic cell nuclear transfer (NT) requires epigenetic reprogramming of the differentiated state of donor cell to a totipotent, embry-onic ground state. Accumulating evidence indicates that in-complete or inappropriate epigenetic reprogramming of do-nor nuclei is likely to be the primary cause of failures in nu-clear transfer. This review summarizes the roles of various epigenetic mechanisms, including DNA methylation, histone acetylation, imprinting, X-chromosome inactivation, te-lomere maintenance and expressions of development-related genes on somatic nuclear transfer. | LI Shijie1,2, DU Weihua1 & LI Ning1 1. State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing 100094, China 2. Department of Biochemistry and Molecular Biology, College of Life Science, Hebei Agriculture University, Baoding 071001, China Correspondence should be addressed to Li Ning (e-mail: ninglbau@ public3.bat.net.cn) | 2004 | Chinese Science Bulletin2004，49，8： | 5 |
| 6 | Absorption,Accumulation and Distribution of Zinc in Highly-Yielding Winter Wheat显示文摘Zinc(Zn) is an important essential microelement for wheat.In order to study the characteristics of Zn absorption,accumulation and distribution in highly-yielding winter wheat(with a grain yield of 9 000 kg ha-1),field experiments were conducted in Gaocheng County of Hebei Province,China.Four winter wheat cultivars,i.e.,Shimai 14,Jifeng 703,Shimai 12,and Shixin 828,and four cultivars,i.e.,Temai 1,Shimai 12,Shixin 531,and Shixin 828,were used in the experiment,during 2004-2005 and 2005-2006,respectively.Plant samples were taken from the plots at each growing stage for Zn concentration analysis.The main results showed that the concentration of Zn in various above-ground organs of wheat was 9.5-112.5 mg kg-1 at different growing stages.The organ with the highest Zn concentration differed with the change of growth center at different growing stages.Accumulation of Zn in leaf blades was the highest among all the organs during early growing period,and more than 50% of the Zn accumulation was distributed to leaf blades before jointing,and higher than that to other organs.In late growing period,however,the accumulation of Zn in grains was the highest,and 58.1% of the Zn accumulation was distributed in grains at maturity.The total accumulation of Zn in wheat plant during its life span ranged from 384.9 to 475.9 g ha-1.The amount of Zn required for the formation of 100 kg grain yield ranged from 4.3 to 5.2 g.All the organs were ordered in such a sequence that leaf blades > spikes > leaf sheaths > stems according to their net absorption and transportation of Zn as well as their contribution to Zn accumulation in grains.58.2-60.3% of the Zn accumulated in grains was redistributed from other organs,mostly from leaf blades.Concentration and accumulation of Zn in all the organs of wheat was high during early and middle growing periods,while accumulation of Zn in grains during late growing period mainly depended on the redistribution from other organs.According to these characteristics of Zn absorption and accumulation,Zn should be applied as seed dressing or basal fertilizer,so as to accelerate the early growth and Zn absorption of wheat. | DANG Hong-kai,LI Rui-qi,SUN Ya-hui,ZHANG Xin-wen and LI Yan-ming College of Agronomy,Agricultural University of Hebei,Baoding 071000,P.R.China | 2010 | Agricultural Sciences in China2010，9，7： | 5 |
| 7 | Weighted Estimates for Marcinkiewicz Integrals with Non-Doubling Measures显示文摘Let μ be a nonnegative Radon measure on R d which satisfies the growth condition μ(B(x,r)) ≤ C0rn for all x ∈Rd and r >0,where C0 is a fixed constant and 0 | Songbai WANG Yinsheng JIANG Baode LI | 2012 | Journal of Mathematical Research with Applications2012，32，2： | 4 |
| 8 | Microstructure and mechanical properties at elevated temperature of Mg-Al-Ni alloys prepared through powder metallurgy显示文摘Mg-Al-Ni alloys were prepared by powder metallurgy, and their microstructure and elevated temperature mechanical properties were investigated. Results indicate that, in addition to α-Mg matrix, both coarse Al_3Ni_2 particles and fine Al Ni nano-particles exist in the Mg-Al-Ni alloys. The strength at 150?C is improved with the increase in Ni content. Mg-18.3Al-8Ni alloy possesses a compressive strength of234.7 MPa and a yield strength of 146.5 MPa. Plasticity is also improved with a low concentration of Ni. Mg-11.3Al-2Ni alloy possesses a compression ratio of 17.3%. The phases of Al_3Ni_2 and Al Ni in the alloys block the movements of grain boundaries and dislocations during the deformation at elevated temperature. The existence of Al Ni phase provides a non-basal slip system, leading to the improvement in plasticity. Finally, the formation mechanism of Al-Ni phases in the process is discussed with thermodynamics and kinetics. | Legan Hou Bingcheng Li Ruizhi Wu Lin Cui Peng Ji Ruiying Long Jinghua Zhang Xinlin Li Anping Dong Baode Sun | 2017 | Journal of Materials Science & Technology2017，33，9： | 4 |
| 9 | Comprehensive Evaluation on Consumption Structure of Rural Residents with Principal Component Analysis in China显示文摘In order to make analysis on consumption structure of rural residents,the paper makes a principle component analysis on consumption expenditure per capita of rural residents in different areas of 2009 based on statistics of China statistical yearbook of 2010.Selecting a principal component,the paper arranges 31 provinces in China in order.Shanghai lists the 1st place with highest marks;coastal provinces in southeastern part,the Northeast,Beijing and Tianjin are at the top;the northern and central parts with Hebei,Shanxi,Hubei as representatives scores minus which is a little lower than that of average;the western part,such as Guizhou,Xizang,Gansu and so on are in far behind.The paper also makes analysis on the consumption structure of rural residents and proposes suggestions on how to accelerate consumption of rural residents. | GUAN Lin,LI Chun-lan,ZHANG Bo School of Science,Hebei Agricultural University,Baoding 071000,China | 2011 | Asian Agricultural Research2011，3，3： | 3 |
| 10 | Effects of Low Temperature Stress and INA Bacteriaon Chlorophyll a Fluorescence Induction Kineticsin Young Fruit of Two Apricot Cultivars显示文摘Effects of low temperature and INA bacteria on the change of chlorophyll a fluorescence inyoung fruit from two apricot cultivars were investigated. Low temperature decreased the potential activity(Fv/Fo) ,conversion efficiency of primary light energy (Fv/Fm)of PS Ⅱ and photochemical quenching (qP) inyoung fruit of two apricot cultivars. Low temperature enhanced non-photochemical quenching qN, decreasingthe quantum yield of photosynthetic electron transfer. The presence of ice nucleating active (INA) bacteria in-tensified the effects of low temperature, raised the injury temperature threshold from - 4℃ to - 2 - - 3℃.INA bacteria can be a factor to induce frost susceptibility of apricot fruit. The amount of damaged PS Ⅱ activi-ty center was related to apricot fruit size and cultivar. | YANG Jian-min , MENG Qing-rui, PENG Wei-xiu, WANG Xue-dong , ZHANG Yuan-hui , SUN Fu-zai, ZHAO Ting-chang and LI Shao-hua(College of Forestry , Hebei Agricultural University, Baoding 071000 , P. R. China Institute of Plant Protection ,Chinese Aeademy of Argricultural Sciences , Beijing 100094 , P. R. China College of Horticultural Sciences ,China Agricultural University , Beijing 100094 , P. R. China) | 2002 | Agricultural Sciences in China2002，1，12： | 3 |
| 11 | Kinetics and Mechanism of Oxidation of Glycol by Dihydroxydiperiodatonickelate ( Ⅳ )Complex in Aqueous Alkaline Medium显示文摘The kinetics of oxidation of glycol by dihydroxydiperiodato nickelate ( Ⅳ) complex (DDN) was studied by spectrophotometry in aqueous alkaline medium in a temperature range of 25-40℃. The reaction was found to be first order with respect to Ni( Ⅳ ) and also to be first order with respect to glycol. The rate increases with the increase in [OH ] and decreases with the increase in [IO-4], showing that dihydroxymonoperiodatonickelate ( Ⅳ )(DMN) is the reactive species of oxidant. Salt effect indicated that the reaction is of ion-dipole type. No free radical was detected. A mechanism of an inner-sphere two-electron transfer reaction involving a preequilibrium between DDN and DMN is proposed, and the rate equation derived from the mechanism can explain all experimental observations. Activation parameters of the rate-determing step and the equilibrium constants were calculated. | WANG An-zhou, LI Feng-mai, LI Zhi-ting, DING Tian-hui and SHAN Jin-huan (Department of Chemistry, Hebei University, Baoding, 071002) | 1992 | Chemical Research in Chinese Universities1992，8，4： | 3 |
| 12 | Cloning and Characterization of a Tau Glutathione S-transferase Subunit Encoding Gene in Gossypium hirsutum显示文摘A predicted tau glutathione S-transferase(GST) subunit encoding gene,named GhGST,was isolated from Gossypium hirsutum with RACE method from SSH library based on Verticillium | MA Zhi-ying,LI Zhi-kun,WANG Xing-fen,MA Jun,ZHANG Gui-yin(Agricultural University of Hebei,Baoding 071001,China) | 2008 | 棉花学报2008，20，S1： | 3 |
| 13 | Effects of novel Fufang Biejia Ruangan Tablets with sheep placenta as substitute for Hominis Placenta on CCl4-induced liver fibrosis显示文摘Objective:Fufang Biejia Ruangan Tablet(FBRT) is widely used for the treatment of liver fibrosis.However,Hominis Placenta(HP),as an important adjuvant of FBRT,has been restricted for medicinal using due to the limited availability,ethical controversy and safety issues.The present study aimed to investigate the therapeutic effects of novel FBRT(N-FBRT) with sheep placenta(SP) as substitute for HP on liver fibrosis and explore its possible mechanisms.Different dosages of SP in N-FBRT were also evaluated.Methods:Rats were subcutaneously injected with CCl_(4)to induce liver fibrosis and then treated with NFBRT and FBRT.The anti-hepatic fibrosis effect was determined based on biomarkers analysis of liver function and hepatic fibrosis,and the liver pathology was visualized by H&E staining and Masson staining.The oxidative stress and inflammatory cytokines were also detected.Immunohistochemical staining of a-SMA,real time PCR and Western blotting were performed to evaluate hepatic stellate cells(HSCs)activation and TGF-β1/Smad signaling pathway.Results:N-FBRT and FBRT could ameliorate CCl_(4)-induced liver fibrosis and improve liver function,as evidenced by lowering serum biomarkers levels of liver function and hepatic fibrosis,and decreasing hepatic Hyp content and collagen deposition,and improving the hepatic morphology and architecture changes.Moreover,the anti-liver fibrosis effect was better when the dosage of SP used in N-FBRT was 1/2 of HP in FBRT.Administration of N-FBRT markedly alleviated oxidative stress and inflammatory cytokines,and inhibited a-SMA expression.Furthermore,the mRNA expression of Col Ⅰ,Col Ⅲ,a-SMA and TGF-β1,and proteins expression of a-SMA,TGF-β1,Smad2/3 and p-Smad2/3 were significantly down-regulated by N-FBRT treatment.Conclusion:SP can be used as substitute for HP to prepare N-FBRT for the treatment of liver fibrosis and the anti-liver fibrosis effect of N-FBRT is achieved by eliminating oxidative stress and inflammation,and inhibiting HSCs activation and ECM production by blocking TGF-β1/Smad signaling pathway. | Baode Shen Li Deng Yuan Liu Ruisheng Li Chengying Shen Xiao Liu Yinchao Li Hailong Yuan | 2022 | Chinese Herbal Medicines2022，14，1： | 2 |
| 14 | Determination of Trace Amount of Polycyclic Aromatic Hydrocarbons in Urban Sewage by Solid-phase Extraction Coupled with High Performance Liquid Chromatograph显示文摘[Method] This study aimed to determine trace amount of polycyclic aromatic hydrocarbons(PAHs) in urban sewage by using solid-phase extraction(SPE) coupled with high performance liquid chromatograph(HPLC).[Method] From the aspects of solid-phase extraction column,elution solvent,elution volume,elution speed and so forth,the test conditions of SPE-HPLC method were optimized,and trace amount of PAHs in urban sewage was determined.[Result] The optimized solid-phase extraction conditions were SUPELCLEAN LC-18 solid-phase extraction column,methylene dichloride as elution solvent,15 ml elution volume,2 ml/min elution speed,5 ml/min loading speed,1 000 ml water with 200 ml methanol loading volume.Under the optimized extraction conditions,the recovery was high,namely 76.3%-105.2%;relative standard deviation was 3.8%-6.0%,showing good precision;detection limit was low,only 0.000 8-0.048 0 μg/L.[Conclusion] This method is user-friendly,with high sensitivity and good precision,and suitable for continuous determination of a large volume of water samples. | WANG Jing-fei1,KANG Quan-ying1,RONG Nan1,2,WU Yi-hong1,LI Hong-bo1 1.Hebei Provincial Academy of Environmental Science,Hebei Provincial Laboratory of Water Environmental Science,Shijiazhuang 050037,China 2.College of Chemistry and Environmental Science,Hebei University,Baoding 071002,China | 2011 | Meteorological and Environmental Research2011，2，10： | 2 |
| 15 | Kinetics and Mechanism of the Oxidation of Glycol by Dihydroxyditelluratoargentate(Ⅲ) with Spectrophotometry显示文摘The kinetics of the oxidation of glycol by dihydroxyditelluratoargentate (Ⅲ) complex(DDA) was studied in alkaline medium with spectrophotometry(in a temperature range of 16\^6—40 ℃). The first order rates with respect to glycol and Ag(Ⅲ) were all found. The rates increased with the increase in [OH -] and decreased with the increase in [TeO 2- 4]. No effect was found with the addition of KNO 3 and no free radical was detected. In view of this, the dihydroxymonotelluratoargentate(Ⅲ) species(DMA) is assumed to be the active species. A plausible mechanism involving a two electron transfer is proposed, and the rate equation derived from the mechanism can explain all experimental observations. Activation parameters of the rate determining step and constants are evaluated. | SHAN Jin huan ** , WANG Li, SHEN Shi gang, SUN Han wen and WANG An zhou (Department of Chemistry, Hebei University, Baoding 071002, P. R. China) | 2000 | Chemical Research in Chinese Universities2000，16，3： | 1 |
| 16 | A sufficent and necessary condition for credibility measures显示文摘 | LI Xiang LIU Baoding | 2006 | International Journal of Uncertainty Fuzziness & Knowledge-Based Systems2006，14，： | 1 |
| 17 | Theoretical analysis for sound wave scattering by parallel cylindrical tubes in boilers显示文摘Although the sonic soot cleaning techniques have been applied in boilers in power plants, petrochemical works and general industries world wide, most of the correlated basic problems have not been well solved yet. By using Helmholtz integral equation, sound wave scattered by heat-exchanger tubes is numerically calculated. Sound field distribution characteristics on the tube surfaces and around the tube group is obtained. The results can be applied to the development of sonic soot cleaning techniques in boilers. | JIANG Genshan (North China Electric Power University Baoding 071003) TIAN Jing LI Xiaodong (Institute of Acoustics, Academia Sinica Beijing 100080) | 2000 | Chinese Journal of Acoustics2000，19，2： | 1 |
| 18 | The role of arbuscular mycorrhiza in zinc uptake by red clover growing in a calcareous soil spiked with various quantities of zinc显示文摘 | CHENG Baode LI X L TAO H Q | 2003 | Chemosphere2003，50，6： | 1 |
| 19 | Influence of high-intensity ultrasound on grain refining performance of Al–5Ti–1B master alloy on aluminium显示文摘 | Yanfeng Han Ke Li Jun Wang Da Shu Baode Sun | 2005 | Materials Science & Engineering A2005，，1： | 1 |
| 20 | Microstructure and strength of needle coke modified ceramic casting molds显示文摘 | Fei Wang Fei Li Bo He Baode Sun | 2013 | Ceramics International2013，，： | 1 |
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