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| 1 | Anti-HIV Ⅰ/Ⅱ Activity and Molecular Cloning of a Novel Mannose/Sialic Acidbinding Lectin from Rhizome of Polygonatum cyrtonema Hua显示文摘 | Jie AN Jin-Zhi LIU Chuan-Fang WU Jian LI Lei DAI Els Van DAMME Jan BALZARINI Erik De CLERCQ Fang CHEN Jin-Ku BAO | 2006 | Acta Biochimica et Biophysica Sinica2006，38，2： | 8 |
| 2 | Computer animations of color markings revealthe function of visual threat signals inNeolamprologus pulcher显示文摘Visual signals, including changes in coloration and color patterns, are frequently used by animalsto convey information. During contests, body coloration and its changes can be used to assess anopponent's state or motivation. Communication of aggressive propensity is particularly importantin group-living animals with a stable dominance hierarchy, as the outcome of aggressive inter-actions determines the social rank of group members. Neolamprologus pulcher is a cooperativelybreeding cichlid showing frequent within-group aggression. Both sexes exhibit two vertical blackstripes on the operculum that vary naturally in shape and darkness. During frontal threat displaysthese patterns are actively exposed to the opponent, suggesting a signaling function. To investi-gate the role of operculum stripes during contests we manipulated their darkness in computeranimated pictures of the fish. We recorded the responses in behavior and stripe darkness of testsubjects to which these animated pictures were presented. Individuals with initially darker stripeswere more aggressive against the animations and showed more operculum threat displays.Operculum stripes of test subjects became darker after exposure to an animation exhibiting a paleoperculum than after exposure to a dark operculum animation, highlighting the role of the dark-ness of this color pattern in opponent assessment. We conclude that (i) the black stripes on theoperculum of N. pulcherare a reliable signal of aggression and dominance, (ii) these markings playan important role in opponent assessment, and (iii) 2D computer animations are well suited to elicitbiologically meaningful short-term aggressive responses in this widely used model system ofsocial evolution. | Valentina BALZARINI Michael TABORSKY Fabienne VILLA Joachim G. FROMMEN | 2017 | Current Zoology2017，63，1： | 3 |
| 3 | 非核苷类逆转录酶抑制剂的研究XVⅢ:4-烯丙基和4-叠氮基取代的三嗪类化合物的合成及抗HIV活性(英文)显示文摘在已有工作基础上,基于分子对接设计合成了8个新的4-烯丙基取代和4-叠氮基取代的二芳基三嗪类衍生物。抗HIV-1活性的测试结果表明所有新化合物均具有抗HIV-1活性。其中化合物7c不仅抑制HIV-1野生株的复制(IC50=0.034μmol·L-1,SI=6475),且对Y181C和K103C双突变酶显示出较强的抑制活性,其IC50值为9.39μmol·L-1,高于奈韦拉平。 | 熊远珍 胡海荣 陈芬儿 Jan Balzarini Christophe Pannecouque Erik De Clercq | 2009 | 药学学报2009，44，2： | 2 |
| 4 | Esophageal squamous cell:MRI evaluation of mediastinum显示文摘 | Petrillo R Balzarini L Bidoli P | 2001 | Gastrointest Radiol2001，16，： | 1 |
| 5 | Pronounced cytostatic activity and bystander effect of a novel series of fluorescent tricyclic acyclovir and ganciclovir derivatives in herpes simplex virus thymidine kinase gene-transduced tumor cell lines显示文摘 | Balzarini J Ostrowski T Goslinski T | 2002 | Gene Ther2002，9，17： | 1 |
| 6 | Microbicide drug candidates to prevent HIV infection显示文摘 | Balzarini J Van Damme L | 2007 | Lancet2007，369，9563： | 1 |
| 7 | Identificationof novel thiocarboxanilide derivatives that suppress a va-riety of drug-resistant mutant human immunodeficiencyvirus type 1 strains at a potency similar to that for wild-type virus显示文摘 | Balzarini J Brouwer W G Dao D C | 1996 | Antimicrob Agents Chemother1996，40，： | 1 |
| 8 | Retention of marked sensitivity to HBY097 in the combined presence of quinoxaline HBY097 and lamivudine 显示文摘 | Balzarini J Pelemans H Riess G | 1998 | Biochem Pharmacol1998，55，5： | 1 |
| 9 | Diagnostic implications of LI , P16,and Ki-67 proteins and HPV DNA in low-grade cervical intraepithelialneoplasia显示文摘 | Gatta LB Berenzi A Balzarini P | 2011 | Int J Gynecol Pathol2011，30，6： | 1 |
| 10 | Pharmacokinetics in mice of the anti-retrovirus agent 9-(2-phosphonylmethoxyethyl)adenine显示文摘 | Naesens L Balzarini J De Clercq E | 1992 | Drug Metab Dispos1992，20，： | 1 |
| 11 | SIV/HIV-1 hybrid virus expressing the reverse transcriptase gene of HIV-1 remains sensitive to HIV-1-specific reverse transoriptase inhibitors after passage in rhesus macaques显示文摘 | BALZARINI J DE CLERCQ E UBERLA K | 1997 | J Acquir Immune Defic Syndr Hum Retrovirol1997，15，1： | 1 |
| 12 | 5'-Nor carbocychc 5'-deoxy 5'-(isobutylthio)adenosine and a 2', 3'-dideoxy -2', 3'-didehydro derivative 显示文摘 | Das SR Schneller SW Balzarini J | 2001 | Antivir Chem Chemother2001，12，2： | 1 |
| 13 | Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics显示文摘 | Balzarini J Keyaerts E Vijgen L | 2006 | Antiviral Research2006，72，1： | 1 |
| 14 | The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine) n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro 显示文摘 | Neyts J Schols D | 1992 | Antiviral Res1992，18，2： | 1 |
| 15 | Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro显示文摘 | Pauwels R Balzarini J | 1988 | Proe Natl Acad Sci1988，85，： | 1 |
| 16 | The mannosespecific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine) n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro显示文摘 | Balzarini J Neyts J Schols D | 1992 | Antiviral Research1992，18，2： | 1 |
| 17 | Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodefficiency virus in vitro显示文摘 | Baba M Pauwels R Balzarini J | 1988 | Proc Natl Acad Sci1988，85，16： | 1 |
| 18 | Diagnostic implications of L1,p16,and Ki-67 proteins and HPV DNA in low-grade cervi-cal intraepithelial neoplasia显示文摘 | Gatta LB Berenzi A Balzarini P | | 0，，06： | 1 |
| 19 | Mannose-specific plant lectins from the Amaryllidaeeae family qualify as efficient microbicides for prevention of infection 显示文摘 | Balzarini J Hatse S Vermeire K | | Antimicrob0，48，10： | 1 |
| 20 | Esophageal squamous cell car- cinoma : MRI evaluation of mediastinum显示文摘 | Petrillo R Balzarini L Bidoli P | 1990 | Gastrointest Radiol1990，15，： | 1 |
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