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116篇 您的检索式:作者名="Balan S"
    题名 作者 年代 出处 被引量
1Epidermal stem cells and skin tissue engineering in hair follicle regeneration显示文摘The reconstitution of a fully organized and functional hair follicle from dissociated cells propagated under defined tissue culture conditions is a challenge stillpending in tissue engineering. The loss of hair follicles caused by injuries or pathologies such as alopecia not only affects the patients' psychological well-being, but also endangers certain inherent functions of the skin. It is then of great interest to find different strategies aiming to regenerate or neogenerate the hair follicle under conditions proper of an adult individual. Based upon current knowledge on the epithelial and dermal cells and their interactions during the embryonic hair generation and adult hair cycling, many researchers have tried to obtain mature hair follicles using different strategies and approaches depending on the causes of hair loss. This review summarizes current advances in the different experimental strategies to regenerate or neogenerate hair follicles, with emphasis on those involving neogenesis of hair follicles in adult individuals using isolated cells and tissue engineering. Most of these experiments were performed using rodent cells, particularly from embryonic or newborn origin. However, no successful strategy to generate human hair follicles from adult cells has yet been reported. This review identifies several issues that should be considered to achieve this objective. Perhaps the most important challenge is to provide threedimensional culture conditions mimicking the structure of living tissue. Improving culture conditions that allow the expansion of specific cells while protecting their inductive properties, as well as methods for selecting populations of epithelial stem cells, should give us the necessary tools to overcome the difficulties that constrain human hair follicle neogenesis. An analysis of patent trends shows that the number of patent applications aimed at hair follicle regeneration and neogenesis has been increasing during the last decade. This field is attractive not only to academic researchers but also to the companies that own almost half of the patents in this field.María Eugenia Balaná Hernán Eduardo Charreau Gustavo Jose Leirós 2015World Journal of Stem Cells2015,7,4:7
2An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gIor the putative gJ显示文摘Balan P Davis-Poynter N Bell S 1994J Gen Virol1994,75,6:1
3State-space exact linearization and stabilization with feedback control in SODE economic models显示文摘BALAN V STAMIN C S 2008Journal of Applied Mathematics and Computing2008,28,:1
4In vitro-in vivo correlation models for metformin after administration of modifiedrelease oral dosage forms to healthy human volunteers显示文摘BALAN G TIMMINS P GREENE D S 2001J Pharm Sci2001,90,8:1
5Life span extension and neuronal cell protection by Drosophila nicotinamidase 显示文摘Balan V Miller G S Kaplun L 2008J Biol Chem2008,283,27:1
6Increased vasopressin transmis- sion from the paraventricular nucleus to the rostral medulla aug- ments cardiorespiratory outflow in chronic intermittent hypoxia-con- ditioned rats显示文摘Kc P Balan K V Tjoe S S 2010J Physiol2010,588,4:1
7The discovery of novel calcium sensing receptor negative allosteric modulators显示文摘Balan G Bauman J Bhattacharya S 2009Bioorg Med Chem Lett2009,19,12:1
8Cradle to grave assessment of existing lignocellulose pretreatment technologies 显示文摘DA C S L CHUNAWT S P S BALAN V 2009Curropin Biotechnol2009,20,3:1
9Risk analysis in global supply chain network environments显示文摘Balan S Vrat P Kumar P 2006European Journal of Operational Research2006,174,3:1
10in vitro-in vivo correlation (IVIVC) models for metfomin after administration of modified-release(MR) oral dosage forms to healthy human volunteers 显示文摘BALAN G TIMMINS P GREENE D S 2001J Pharm Sci2001,90,8:1
11' Cradle- to-grave'assessment of existing lignocellulose pretreatment technologies显示文摘da Costa Sousa L Chundawat S PS Balan V 2009Current Opinion in Bioteehnolagy2009,20,3:1
12Site-specific PEGylation of protein disulfide bonds using a three-carbon bridge 显示文摘Balan S Choi JW Godwin A 2007Bioconjugate Chemistry2007,18,1:1
13Radiation induced oral mucositis 显示文摘Ps S K Balan A Sankar A 2009Indian J Palliat Care2009,15,2:1
14Disulfide bridge based PEGylation of proteins 显示文摘Balan S Brocchini S Godwin A 2008Advanced Drug Delivery Reviews2008,60,1:1
15Mushroom spent straw: a potential substrate for an ethanol-based biorefinery显示文摘Balan V da Costa Sousa L Chundawat S 2008Journal of Industrial Microbiology & Biotechnology2008,35,5:1
16Asymptotic results with general- ized estimating equations for longitudinal data显示文摘Balan R M Kratina I S 2005The Annals of Statistics2005,33,2:1
17Box-Behnken design in the development of optimized complex medium for phenol degradation using Pseudomonas putida(NICM2174) 显示文摘Annadurai G Mathalai Balan S Murugesan T 1999Bioprocess Engineering1999,21,:1
18The natural genomic variability of poliovirus analyzed by a restriction fragment length polymorphism assay显示文摘Balanant J Guillot S Candrea A 1991Virology1991,184,:1
19Mesenchymal stromal ceils in the antimicrobial host response of hematopoietic stem cell recipients with graft-versus-host disease-friends or foes&quest显示文摘Balan A Lucchini G Schmidt S 2014Leukemia2014,28,10:1
20The natural genomic varia- bility of poliovirus analyzed by a restriction fragment length polymor- phism assay 显示文摘Balanant J Guillot S Candrea A 1994Virology1994,184,2:1
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