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| 1 | Hepatitis E virus: Epidemiology, diagnosis, clinical manifestations, and treatment显示文摘The hepatitis E virus(HEV)is the fifth known form of viral hepatitis and was first recognized as the cause of an epidemic of unexplained acute hepatitis in the early 1980s.Globally,it is one of the most frequent causes of acute viral hepatitis.The majority of HEV infections are asymptomatic and lead to the spontaneous clearance of the virus.Among the eight different genotypes identified to date,HEV genotype 1(HEV1),HEV2,HEV3,and HEV4 are the most frequent genotypes causing infections in humans.HEV1 and HEV2 are prevalent in developing regions and able to result in large-scale outbreaks originating from contaminated water supplies.They are also responsible for severe hepatitis in pregnant patients and infants.In contrast,HEV3 and HEV4 are zoonotic,and the transmission of these genotypes to humans occurs mainly through the fecal contamination of water and consumption of contaminated meat from infected animals.Their main reservoir is the pig,and they are mostly encountered in developed countries.The major risk groups for HEV infection and its ensuing adverse consequences are pregnant women,infants,older people,immunocompromised individuals,patients with underlying chronic liver diseases,and workers that come into close contact with HEV-infected animals.In the clinical perspective,HEV infections have diverse clinical manifestations including acute and self-limiting hepatitis,acute-on-chronic liver disease,chronic hepatitis,cirrhosis,and liver failure.Although HEV mainly results in acute selflimiting infection,chronic HEV infection may occur among immunocompromised patients(e.g.,solid-organ transplant recipients).Additionally,HEV-associated extrahepatic manifestations involving various organs have been reported in the last decade,although the causal link for many of them still needs to be proven.Ribavirin and interferon-alpha are the most widely used agents for the treatment of HEV infections with a certain level of success.However,ribavirin is contraindicated in pregnant patients,and interferon-alpha cannot be used in most transplant recipients.Therefore,there is an urgent need for novel antiviral compounds that are safe and effective particularly for patients having contraindications for ribavirin or interferon-alpha and infected by the ribavirinresistant HEV.In this review article,a literature search using PubMed and MEDLINE databases was performed,up to March 2020.Only the articles published in English were reviewed. | Abdullah Tarık Aslan Hatice Yasemin Balaban | 2020 | World Journal of Gastroenterology2020，26，37： | 15 |
| 2 | Liver immunology and herbal treatment显示文摘Beyond the metabolic functions, the liver recently has been defined as an organ of immune system(IS), which have central regulatory role for innate and adaptive immunity. The liver keeps a delicate balance between hepatic screening of pathogenic antigens and immune tolerance to self-antigens. Herbal treatments with immunological effects have potential to alter this hepatic immune balance towards either therapeutic side or diseases side by inducing liver injury via hepatotoxicity or initiation of autoimmune diseases. Most commonly known herbal treatments, which have therapeutic effect on liver and IS, have proven via in vitro, in vivo, and/or clinical studies were summarized in this review. | Yasemin H Balaban Ceylan Aka Ufuk Koca-Caliskan | 2017 | World Journal of Hepatology2017，9，17： | 3 |
| 3 | Redefining and Redesigning Hospital Discharge to Enhance Patient Care: A Randomized Controlled Study显示文摘 | Richard B. Balaban Joel S. Weissman Peter A. Samuel Stephanie Woolhandler | 2008 | Journal of General Internal Medicine2008，，8： | 2 |
| 4 | Multi-center evaluation of oxidation-reduction potential by the MiOXSYS in males with abnormal semen显示文摘According to the World Health Organization(WHO),oxidative stress(OS)is a significant contributor to male infertility.SeminalOS can be measured by a number of assays,all of which are either costly or time sensitive and/or require large semen volume andcomplex instrumentation.One less expensive alternative is to quantify the oxidation-reduction potential(ORP)with the MiOXSYS.In this international multi-center study,we assessed whether ORP levels measured by the MiOXSYS could distinguish semensamples that fall within the 2010 WHO normal reference values from those that do not.Semen samples were collected from 2092patients in 9 countries;ORP was normalized to sperm concentration(mV/10^6 sperm/ml).Only those samples with a concentration>1×10^6 sperm ml1 were in eluded.The results showed that 199 samples fell within the WHO no rmal refere nee range while theremaining 1893 samples did not meet one or more of the criteria.ORP was negatively correlated with all semen parameters(P <0.01)except volume.The area under the curve for ORP was 0.765.The ORP cut-off value(1.34 mV/10^6 sperm/ml)was able todifferentiate specimens with abnormal semen parameters with 98.1%sensitivity,40.6%specificity,94.7%positive predictivevalue(PPV)and 66.6%negative predictive value(NPV).When used as an adjunct to traditional semen analysis,ORP levels mayhelp identify altered functional status of spermatozoa caused by OS in cases of idiopathic male infertility and in male partners ofcouples sufferi ng recurre nt pregna ncy loss,and thereby directi ng these men to relevant medical therapies and lifestyle modificati ons. | Ashok Agarwal Manesh Kumar Panner Selvam Mohamed Arafa Hiroshi Okada Sheryl Homa Aideen Killeen Basak Balaban Ramadan Saleh Abdullah Armagan Shubhadeep Roychoudhury Suresh Sikka | 2019 | Asian Journal of Andrology2019，21，6： | 2 |
| 5 | Strategies of heavy metal uptake by three plant species growing near a metal smelter显示文摘 | H Dahmani-Muller F van Oort B Gélie M Balabane | 2000 | Environmental Pollution2000，，2： | 2 |
| 6 | Staphylococcal enterotoxins显示文摘 | Balaban N Rasooly A | 2000 | Food Microbio2000，61，1： | 1 |
| 7 | Composition,color and mechanical characteristics of pretreated candied chestnuts显示文摘 | KOREL F BALABAN M O | 2006 | International Journal of Food Properties2006，9，3： | 1 |
| 8 | The effect of pronuclezr morphology on embryo quzlity parameters and blastocyst trznsfer outcome显示文摘 | \ Balaban B Unman B Isiklzr A | 2001 | Hum Eeprod2001，16，11： | 1 |
| 9 | Comparison of Minolta colorimeter and machine vision system in measuring colour of irradiated Atlantic salmon显示文摘 | Yagiz Yavuz Balaban Murat O Kristinsson Hordur G | | 0，，04： | 1 |
| 10 | Early rehabilitation outcome in patients with middle cerebral artery stroke显示文摘 | Balaban B Tok F Yavuz F | 2011 | Neuroscience letters2011，498，3： | 1 |
| 11 | A randomized controlled study of human day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation显示文摘 | Balaban B Urman B Ata B | 2008 | Hum Reprod2008，23，9： | 1 |
| 12 | The effect of running on serum and red cell ferritin: Alongitudinal comparison显示文摘 | Balaban EP Snell P Stray GJ | 1995 | Int Sports Med1995，16，5： | 1 |
| 13 | A chimeric peptide composed of a dermaseptin derivative and an RNAⅢ-inhibiting peptide prevents graft-associated infections by antibiotic-resistant staphylococci显示文摘 | Balaban N Gov Y Giacometti A | 2004 | Antimicrob Agents Chemother2004，48，7： | 1 |
| 14 | A randomized controlled study of human Day3 embryo cryopreservation by slow freezing or vitrification:vitrification is associated with higher survival,metabolism and blastocyst formation显示文摘 | Balaban B Urman B Ata B | 2008 | Hum Reprod2008，23，： | 1 |
| 15 | Inactivation of polyphenol oxidase in muscadine grape juice by dense phase-CO2 processing显示文摘 | POZO-INSFRAN D BALABAN M O TALCOTT S T | | 0，，07： | 1 |
| 16 | Evaluation of Color Parameters in a Machine Vision Analysis of Carbon Monoxide-Treated Fish-Part Ⅰ显示文摘 | Balaban Murat O Kristinsson Hordur G Otwell W.Steven | | 0，，02： | 1 |
| 17 | Severe cytoplasmic ab-normalities of the oocyte decrease cryosurvival and subse-quent embryonic development of cryopreserved embryos显示文摘 | Balaban B Ata B Isiklar A | | 0，，8： | 1 |
| 18 | Botulinum toxin a treatment in children with cerebral palsy:its effects on walking and energy expenditure 显示文摘 | BALABAN B TOK F TAN A K | 2012 | Am J Phys Med Rehabil2012，91，1： | 1 |
| 19 | Protein kinase C mediates basie fibroblast growth factor pm- lection of endothelial cells against radiation - induced apoptosis 显示文摘 | HAIMOVlTZ FRIEDMAN A BALABAN N MCI OUGHI IN M el al | 1994 | Cancer Res1994，54，10： | 1 |
| 20 | Sports anemia显示文摘 | Balaban EP | 1992 | Clin Sports Med1992，11，2： | 1 |
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