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29篇 您的检索式:作者名="Backendorf"
    题名 作者 年代 出处 被引量
1Skin cornification proteins provide global link between ROS detoxification and cell migration during wound heal-ing显示文摘Vermeij WP Backendorf C 0,,:1
2Apoptin: therapeutic potential of an early sensor of carcinogenic transformation显示文摘Backendorf C Visser AE de Boer AG 2008Annu Rev Pharmacol Toxicol2008,48,2:1
3Apoptin:therapeutic potential of an early sensor of carcinogenic transformation显示文摘Backendorf C Visser AE de Boer AG 0,,:1
4Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 0,,02:1
5Apoptin: thera- peutic potential of an early sensorof carcinogenic transformation 显示文摘Backendorf C Visser AE de Boer AG 2008Annu Rev Pharmaeol Toxieol2008,48,68:1
6Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes显示文摘Karim R Meyers C Backendorf C 0,,03:1
7Apoptin特写:新治疗展望(英文)显示文摘Apoptin诱导人转化细胞而不是正常细胞的凋亡,特异性地感知转化细胞的信号并被激活。这些特性使得Apoptin成为一种用于与细胞转化相关的肿瘤以及自身免疫性疾病(如风湿性关节炎)的前景型制剂。不同研究小组相继报道了细胞转化特异性过程和Apoptin凋亡诱导的相关性,如肿瘤特异激酶激活以及p53阴性转化细胞中细胞分裂后期启动复合物(APC)即起关键作用。体内外前临床基因治疗研究和蛋白转导试验充分显示Apoptin作为治疗制剂的有效性和安全性。化疗药物,如etoposide、paclitaxel或methotrexate(甲氨蝶呤)与Apoptin的联合治疗,协同增强了对肿瘤细胞的毒效应。对Apoptin感知的细胞转化信号通路的深入研究,将有助于在分子水平上进一步揭示癌发生或风湿性关节炎疾病的病理机制。Apoptin工艺与其它化疗制剂的结合,将为细胞转化相关疾病提供新颖的治疗策略。章应慧 Sharon J Olijslagers Claude Backendorf Mathieu HM Noteborn 2006医学分子生物学杂志2006,3,6:1
8Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes显示文摘Karim R Meyers C Backendorf C 0,,03:1
9Additive cytotoxic effect of Apoptin and chemotherapeutic agents paditaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Cain Pharmacol Toxicol2007,100,2:1
10Accurate non-invasive image-based cytotoxicity assays for cultured ceils 显示文摘Marques-Gallego P den Dulk H Backendorf C 2010BMC Biotechnol2010,10,:1
11Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells显示文摘Danen-Van Oorschot A A Fischer D F Grimbergen J M Klein B Zhuang S Falkenburg J H Backendorf C Quax P H Van der Eb A J Noteborn M H 1997Proc Natl Acad Sci USA1997,94,11:1
12Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Pharmacol Toxicol2007,100,2:1
13Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes显示文摘Karim R Meyers C Backendorf C 2011PLoS One2011,6,17:1
14ROS quenching potential of the epidermal cornifled cell envelope显示文摘Vermeij WP Alia A Backendorf C 2011J Invest Dermatol2011,131,7:1
15Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumor cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Phannaeol Toxieol2007,100,2:1
16Apoptin:therapeutic potential of an early sensor of carcinogenic transfor-mation显示文摘Backendorf C Visser AE de Boer AG 2008Annu Rev Pharmacol Toxicol2008,48,:1
17Human papiUomavirus deregulates the response of a cellular network comprising of chemo- tactic and proinflammatory genes 显示文摘Karim R Meyers C Backendorf C 2011PLoS One2011,6,17:1
18Promoter analysis in the human SPRR gene family显示文摘Fischer DF Backendorf C 2005Methods Mol Biol2005,289,:1
19Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Pharmacol Toxicol2007,100,2:1
20Additive cytotoxic effect of apeptin and chemotherapeutic agents paclitaxel and etopeside on human tumour cells 显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Pharmacol Toxicol2007,100,2:1
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