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229篇 您的检索式:作者名="Baba J"
    题名 作者 年代 出处 被引量
1AKT and ERK1/2 signaling in intrahepatic cholangiocarcinoma显示文摘Intrahepatic cholangiocarcinomas (ICC) are neoplasms that originate from cholangiocytes and can occur at any level of the biliary tree. Surgical resection is the current therapy of choice for this highly aggressive cancer. However, the 5-year survival still is poor, with high recurrence rates. Due to the intrahepatic growth a signifi cant proportion of patients present with advanced disease and are not candidates for curative surgery or transplantation. The existing palliative options are of limited benefit and there is a great necessity for novel therapeutic options. In this article we review the role of the phosphoinositide 3-kinase(PI3K)/ AKT and extracellular regulated kinase (ERK) signaling pathways in ICC and present new data on the prognostic value of these protein kinases. Finally, we discuss future upcoming therapeutic options based on targeting these signaling pathways.KJ Schmitz H Lang J Wohlschlaeger GC Sotiropoulos H Reis KW Schmid HA Baba 2007World Journal of Gastroenterology2007,13,48:8
2Catalytic Properties of Low-valent Lanthanide Species Introduced into Y-Zeolite 显示文摘Baba T Kim G J Ono Y 1992J Chem Soc Faraday Trans1992,88,6:2
3Analysis of finite 2-D photonic crystals of columns and light wave devices using the scattering matrix method显示文摘J Yonekura M Ikeda and T Baba 1999Journal of Light wave Technology1999,17,8:1
4Deletion allele of angiotensin-eonverting enzyme gene increases risk of essential hypertension in japanese men: the Suita study显示文摘Higaki J Baba S Katsuya T 2000Circulation2000,101,17:1
5Academic entrepre- neurship and exchange of scientific resources: Materi- al transfer in life and materials sciences in Japanese universities显示文摘Shibayama S Walsh J P Baba Y 2012American Sociological Review2012,,7:1
6Precautions for the structural analysis of the gelatinous layer in tension wood 显示文摘CLAIR B GRIL J BABA K 2005IAWA Journal2005,26,2:1
7Analysis of finite 2-D photonic crystals of columns and light wave devices using the scattering matrix method显示文摘 M Ikeda and T Baba 1999Journal of Light wave Technology1999,17,:1
8Strong and significant relationship between aggregation of major coronary risk factors and accleration of carotid atheroscle rosis in general population of a Japanese city:the Suita Study显示文摘Manami T Baba S Ogata J 0,,15:1
9Aldose reductase (AKR1B3) regulates the accumulation of advanced glycosylation end products (AGEs) and the expression of AGE receptor (RAGE)显示文摘Baba SP Hellmarm J Srivastava S 2011Chem Biol Interact2011,191,13:1
10Bisphenol A induces en- doplasmic reticulum stress-associated apoptosis in mouse non-parenchymal hepatocytes 显示文摘Asahi J Kamo H Baba R 2010Life Sci2010,87,:1
11Thermal stability of electrolytes with LixCoO2 cathode or lithiated carbon anode显示文摘Yamaki J Baba Y Katayama N 2003Journal of power sources2003,119,:1
12Strong and significant relationship between aggregation of major coronary risk factors and accleration of carotid atherosclerosis in general population of a Japanese city The Suita Study 显示文摘Mannami T Baba S Ogata J 2000Arch Intern Med2000,160,15:1
13Catalytic properties of low-valent lanthanide species introduced into Y-zeolite显示文摘T Baba J G Kim Y Ono 1992J Chem Soc Faraday Trans1992,88,6:1
14Inducible beat shock protein 70 in rat cardiac allograft and its immunohistochemical localization in cardiac myocytes 显示文摘Baba H A Schmid C Wilhelm M J 1997Transplantation1997,64,7:1
15Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro显示文摘 Pauwels R Balzarini J 1988Proe Natl Acad Sci1988,85,:1
16Epstein-Barr virus/humanvect or provides high-level,long-term expression of alphal-antitrypsin in mice显示文摘Stoll SM Sclimenti CR Baba E J 2001Mol Ther2001,4,2:1
17Heat shock protein 72 and apoptosis indicate cardiac decompensation during early multiple organ failure in sheep显示文摘Baba HA Wohlschlaeger J Stubbe HD 2004Intensive Care Med2004,30,7:1
18Structure and expression of the Ah receptor repressor gene显示文摘Baba T Mimura J Gradin K 2001Journal of Biological Chemistry2001,276,33:1
19Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodefficiency virus in vitro显示文摘Baba M Pauwels R Balzarini J 1988Proc Natl Acad Sci1988,85,16:1
20Studies on the constituents of Pu- erada lobata显示文摘Kinjo J E Furusawa J I Baba J 1987Chem Pharm Bull1987,35,:1
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