|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Six-year outcomes in neovascular age-related macular degeneration with ranibizumab显示文摘● AIM: To evaluate the outcomes of ≥6y ranibizumab therapy in neovascular age-related macular degeneration(AMD).● METHODS: HELIX was a retrospective, observational effeciveness study using medical records of patients treated in three clinics in Belgium. Patients had neovascular AMD and were initially treated with intravitreal ranibizumab(0.5 mg) between November 1, 2007 and October 31, 2008, had ≥6y of data available, and were treated on an ongoing, as-needed basis. Outcomes included best-corrected visual acuity(BCVA) and central retinal thickness(CRT).● RESULTS: The sample consisted of 88 eyes from 69 patients. Mean age was 76.4±6.5y, most patients were female(62.3%). Most eyes(62.5%) were treatment-naive, 33 previously treated eyes had received predominantly other anti-vascular endothelial growth factor agents and verteporfin. Mean baseline BCVA was 57.4±12.7 ETDRS letters and CRT was 292±86 μm. On average, patients received 20.6±11.9 ranibizumab injections over the ≥6y. Intervals between injections were on average 12.7±16.1wk. Mean change in BCVA from baseline to last observation for the sample was less than one letter(-0.9±17.3 letters), with an average loss of-3.2±15.6 letters in previously treated eyes versus a gain of 0.6±18.4 letters in treatment-na?ve eyes. When considering a loss of <15 letters over 6y as stabilization of disease, 75.9% of all eyes showed a positive(improvement or stabilization) outcome. Mean change in CRT from baseline to last observation for the sample was-26.9±148.4 μm with the greatest reduction observed in treatment-naive eyes.● CONCLUSION: This retrospective study of 69 neovascular AMD patients treated for ≥6y with ranibizumab demonstrates long-term visual stabilization. In light of the natural evolution of the disease, these data confirm that ranibizumab is effective long-term under real-world conditions of heterogeneity of patients, clinicians, and centers. | Julie Jacob Heidi Brié Anita Leys Laurent Levecq Filip Mevgaerts Kris Denhaerynck Stefaan Vancayzeele Eline Van Craeyveld Ivo Abraham Karen MacDonald | 2017 | International Journal of Ophthalmology(English edition)2017，10，1： | 5 |
| 2 | Efficiency and the Bear: Short Sales and Markets Around the World显示文摘 | ARTURO BRIS WILLIAM N. GOETZMANN NING ZHU | 2007 | The Journal of Finance2007，，： | 2 |
| 3 | A data fusion-based framework to integrate multi-source VGI in an authoritative land use database显示文摘Updating an authoritative Land Use and Land Cover(LULC)database requires many resources.Volunteered geographic information(VGI)involves citizens in the collection of data about their spatial environment.There is a growing interest in using existing VGI to update authoritative databases.This paper presents a framework aimed at integrating multi-source VGI based on a data fusion technique,in order to update an authoritative land use database.Each VGI data source is considered to be an independent source of information,which is fused together using Dempster-Shafer Theory(DST).The framework is tested in the updating of the authoritative land use data produced by the French National Mapping Agency.Four data sets were collected from several in-situ and remote campaigns run between 2018 and 2020 by contributors with varying profiles.The data fusion approach achieved an overall accuracy of 85.6%for the 144 features having at least two contributions when the confidence threshold was set to 0.05.Despite the heterogeneity and limited amount of VGI used,the results are promising,with 99%of the LU polygons updated or enriched.These results show the potential of using multi-source VGI to update or enrich authoritative LU data and potentially LULC data more generally。 | Lanfa Liu Ana-Maria Olteanu-Raimond Laurence Jolivet Arnaud-le Bris Linda See | 2021 | International Journal of Digital Earth2021，14，4： | 2 |
| 4 | Micro-macro models for viscoelastic fluids: modelling, mathematics and numerics Dedicated to the NSFC-CNRS Chinese-French summer institute on fluid mechanics in 2010显示文摘 | LE BRIS Claude LELIVRE Tony | 2012 | Science China Mathematics2012，55，1： | 2 |
| 5 | 原发性血小板增多症巨核系祖细胞体外自主性生长及Tpo作用的探讨显示文摘目的 研究原发性血小板增多症 (ET)巨核系祖细胞的体外自主性生长以及Tpo对其生长的作用。方法 用ET患者骨髓纯化CD3 4+ 细胞以及不同浓度的骨髓和外周血单个核细胞进行体外培养 ,检测其对自发性CFU MK形成的影响 ;用RT PCR技术检测液体培养自发性生长细胞的Tpo的自主分泌和旁分泌 ;观察CD3 4+ 细胞培养中加入Tpo对CFU MK形成的影响。结果 体外培养纯化CD3 4+ 细胞无自发性CFU MK形成 ,单个核细胞稀释到一定浓度 (10 4 /ml或 10 3 /ml)时自发性集落消失 ;液体培养自发性生长细胞无TpomRNA的表达 ;CD3 4+ 细胞培养中加入Tpo后可形成CFU MK。结论 ET患者的体外自发性CFU MK形成并非巨核系祖细胞的自主性生长所致 ,与Tpo的自主分泌或旁分泌也无关。 | 李艳 Jean Brière 翟明 | 2001 | 中华血液学杂志2001，22，6： | 2 |
| 6 | Condensation of gly-oxal with triethylenetetraamine:Stereochemistry,cyclizationand deprotection 显示文摘 | Herve G Bernard H Le Bris N | 1999 | Tetrahedron Letters*1999，40，13： | 1 |
| 7 | Do Insider Trading Laws Work ?显示文摘 | Bris Arturo | 2005 | European Financial Management2005，11，3： | 1 |
| 8 | Dynamic power control in a fading down- link channel subiect to an energy eonstraint显示文摘 | Bris A Zachariadis K E | 2007 | Queuing System2007，55，1： | 1 |
| 9 | SNPs in forensic genetics:a review on SNP typing methodologies显示文摘 | Sobrino B Brión M Carracedo A | 2005 | Forensic Sci Int2005，154，： | 1 |
| 10 | Cyclohexanedione bisaminals as intermediates for cyclen,homocyclen,and cyclam synthesis显示文摘 | Prokhorov Anton Bris Nathalie Le Bernard Helene | 2006 | Synthetic Communica-tions2006，36，21： | 1 |
| 11 | Mineralogical gradients associated with alvinellids at deep-sea hydrothermal vents显示文摘 | Zbinden M Bris N L Compere P | 2003 | Deep-Sea Research 12003，50，2： | 1 |
| 12 | Isolated granulocytic sarcoma followed by acute myelogenous leukemia type FAB-M2 associated with inversion 16 and trisomies 9 and 22显示文摘 | Morel F Herry A Bris M L | 2002 | Leukemia2002，16，12： | 1 |
| 13 | Eosinophils in asthma and airway hyperresponsiveness显示文摘 | Bri^itlingCE Pavord ID | 2004 | Am J Respir Crit Care Med2004，169，1： | 1 |
| 14 | Efficiency and the bear: Short sales and markets around the world 显示文摘 | Bris A Goetzmann W N Zhu N | 2007 | The Journal of Finance2007，62，3： | 1 |
| 15 | Clonality analysis of hem-atopoiesis in essential thrombocythemia:advantages of studying T lymphocytes and platelets显示文摘 | el-Kassar N Hetet G Bri(e)re J | | 0，，： | 1 |
| 16 | A street deposit sampling method for metal and hydrocarbon contamination assessment 显示文摘 | Bris F J Garnaud S Apperry N | 1999 | Sci Total Environ1999，235，13： | 1 |
| 17 | A street deposit sampling method for metal and hydrocarbon contamination assessment 显示文摘 | Bris F J Garnaud S Apperry N | 1999 | Sci Total Environ1999，235，13： | 1 |
| 18 | A new chemical analy-zer for in situ measurement of nitrate and total sulfide over hydro- thermal vent biological communities 显示文摘 | Le Bris N Sarradin P M Birot D | 2000 | Marine Chemistry2000，72，： | 1 |
| 19 | Nonlinear Sehrtidinger evolution equations 显示文摘 | BRI~ZIS H GALLOUET T | 1980 | Nonlinear Analysis1980，4，4： | 1 |
| 20 | The costs of bankruptcy显示文摘 | Bris A Welch I Zhu N | | 0，，03： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员