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	题名	作者	年代	出处	被引量
1	Gastrointestinal and liver disease in patients with schizophrenia:A narrative review显示文摘Schizophrenia is a severe mental illness which can have a devastating impact onan individual’s quality of life. Comorbidities are high amongst patients and lifeexpectancy is approximately 15 years less than the general population. Despite thewell-known increased mortality, little is known about the impact of gastrointestinaland liver disease on patients with schizophrenia. We aimed to reviewthe literature and to make recommendations regarding future care. Literaturesearches were performed on PubMed to identify studies related to gastrointestinaland liver disease in patients with schizophrenia. High rates of chronic liverdisease were reported, with Non-Alcoholic Fatty Liver Disease being of particularconcern;antipsychotics and metabolic syndrome were contributing factors. Ratesof acute liver failure were low but have been associated with antipsychotic useand paracetamol overdose. Coeliac disease has historically been linked to schizophrenia;however, recent research suggests that a causal link is yet to be proven.Evidence is emerging regarding the relationships between schizophrenia andpeptic ulcer disease, inflammatory bowel disease and irritable bowel syndrome;clinical vigilance regarding these conditions should be high. Patients with schizophreniapoorly engage with bowel cancer screening programmes, leading to latediagnosis and increased mortality. Clozapine induced constipation is a significantissue for many patients and requires close monitoring. There is a significantburden of gastrointestinal and liver disease amongst patients with schizophrenia.Better levels of support from all members of the medical team are essential toensure that appropriate, timely care is provided.	Rebecca K Grant William M Brindle Mhairi C Donnelly Pauline M McConville Thomas G Stroud Lorenzo Bandieri John N Plevris	2022	World Journal of Gastroenterology2022，28，38：	2
2	Application of chemometrics to 1H - NMR spectroscopic data to investigate a relationship between human serum met - abolic profiles and hypertension 显示文摘	Brindle JT Nicholson JK Schofield PM	2003	Analyst2003，128，1：	1
3	Surgical treatment of aortic hypoplasia in infants and children with biventricular hearts显示文摘	Van Arsdell GS Brindle M	1999	Ann Thorac Surg1999，68，6：	1
4	Mitochondrial citrate synthase is immobilized in vivo显示文摘	Haggie P M Brindle K M	1999	J Biol Chem1999，274，7：	1
5	Nitrification in a bubbleless oxygen mass transfer membrane bioreactor显示文摘	Brindle K Stephenson T	1996	Water Sci Technoi1996，34，9：	1
6	Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension显示文摘	BRINDLE J T NICHOLSON J K SCHOFIELD P M	2003	Analyst2003，128，1：	1
7	Use of wound dressings to enhance prevention of pressure ulcers caused by medical de- vices显示文摘	Black J Alves P Brindle CT	2015	International Wound Journal2015，12，3：	1
8	Analysis of the ability of three probes targetin g the outer acrosomal membrane or acrosomal contents to detect the acrosome reac tion in human spermatozoa显示文摘	Brindle J P	1993	Hum Reprod1993，8，10：	1
9	Estimation of the intracellular free ADP concentration by 19F NMR studies of fluorine-labeled yeast phosphoglycerate kinase in vivo显示文摘	Williams S P Fulton A M Brindle K M	1993	Biochemistry1993，32，18：	1
10	The susceptibili- ty of tumors to the antivascular drug combretastatin A4 phosphate correlates with vascular permeability 显示文摘	Beauregard DA Hill SA Chaplin D J Brindle KM	2001	Cancer Res2001，61，18：	1
11	The application of membrane biologicalreactors for the treatment of wastewater 显示文摘	Brindle K Stephenson T	1996	Biotechnology andBioengineering1996，49，6：	1
12	The application of membrane biological reactors for the treatment of wastewaters显示文摘	Brindle K Stephenson T	1996	Biotechnology and Bioengineering1996，49，6：	1
13	Progesterone and ovulation acroo stages of the transtition to menopause显示文摘	O'CONNOR KA FERRELL R BRINDLE E		0，，06：	1
14	Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics显示文摘	ANTTI H HOLMES E	2002	Nat Med2002，8，12：	1
15	19F NMR measurements of the rotational mobility of proteins in vivo 显示文摘	Williams S P Haggie P M Brindle K M	1997	BiophysJ1997，72，1：	1
16	Catalytic pyrolysis of tyres:influence of catalyst temperature显示文摘	Williams P T Brindle A J	2002	Fuel2002，81，：	1
17	Validity of methods for analyzing urinary steroid data to detect ovula- tion in athletes显示文摘	MCCONNELL H J O'CONNOR K A BRINDLE E	2002	Med Sci Sport Exe2002，34，：	1
18	Application of orthogonal signal correction to minimise the effects of physical and biological variation in high resolution 1H NMR spectra of biofluids显示文摘	Beckwith-Hall BM Brindle JT Barton RH	2002	Analyst2002，127，10：	1
19	Rapid andheart disease using1 H NMR-based metabonomics 显示文摘	BRINDLE J T ANTTI H HOLMES E	2002	J NatMed2002，8，12：	1
20	hnmune cell-induced synthesis of NO and reactive oxygen species in lymphoma cells causes Iheir death by apoptosis 显示文摘	Hu DE Brindle KM	2005	FEBS Lett2005，579，13：	1

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