维普中文期刊产品整合服务
279篇 您的检索式:作者名="BOSCOLO"
    题名 作者 年代 出处 被引量
1模拟失重大鼠大脑中动脉与肠系膜小动脉生物力学行为的比较显示文摘为进一步阐明短期失重下血管的适应性改变及其重力性对抗措施的机理,本文对3d模拟失重组(SUS)、对抗措施组(STD,每日恢复正常站立体位1h模拟-Gx重力)及对照组(CON)大鼠大脑中动脉和肠系膜第三级小动脉的被动和主动生物力学特性进行了分析。所研究的生物力学参数包括:被动血管的表观刚度(β)、被动和主动血管的周向应力(σθ)-应变(εθ)关系及其增量弹性模量(Einc,p),和平滑肌收缩活动所致的激活增量弹性模量(Einc,a)。主动血管生物力学特性分析结果显示,肌源性紧张度的调节对失重下血管的适应具有重要意义:(1)SUS组肠系膜第三级小动脉的主动σθ-εθ曲线与其被动态曲线基本一致,表明通过肌紧张度调节使σθ恢复正常的功能基本丧失;但每日1h的-Gx重力暴露则可完全防止此功能减退;(2)SUS组大脑中动脉的主动σθ-εθ曲线较其被动曲线明显左移,不同压力下εθ始终相对稳定,σθ也趋于正常;且每日短时-Gx重力不能防止这种功能亢进。另一方面,对被动血管生物力学特性的分析则提示,不同血管的间质成分可能有不同重塑(remodeling)变化,如失重暴露时间进一步延长,将可能观察到有显著意义的重要变化。总之,本文血管生物力学特性分析对阐明失重环境下血管适应机理及其重力性对抗措施具有重要意义。程九华 BOSCOLO Marco 林乐健 白云刚 张向 马进 张立藩 2009生理学报2009,61,4:2
2Network Component Analysis: Reconstruction of Regulatory Signals in Biological Systems显示文摘Liao J C Boscolo R Yang Y L 2003Proceedings of the National Academy of Sciences2003,100,15:1
3Network component analysis: reconstruction of regulatory signals in biological systems显示文摘LIAO J C BOSCOLO R YANG Y L 2003Proceedings of the National''s Academy of Sciences ( PNAS)2003,100,15:1
4A generalized framework for network component analysis显示文摘BOSCOLO R SABATTI C LIAO J C 2005IEEE Transaction on Computational Biology and Bioinformatics2005,2,:1
5How do rat cortical cells cultured with aluminum die:necrosis or apoptosis?显示文摘Zhang QL Boscolo P Niu PY 2008Int J Immunopathol Pharmacol2008,21,1:1
6Muhipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice显示文摘Khan ZA Boscolo E Picard A 2008J Clin Invest2008,118,7:1
7Biological and clinical characterization of paclitaxel poliglumex (PPX,CT-2103),a macromolecular polymer-drug conjugate显示文摘Zhang QL Boscolo P Niu PY 2006Int J Nanomedicine2006,1,4:1
8Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice显示文摘Khan ZA Boscolo E Picard A 2008J Clin Invest2008,118,:1
9Kininergic system and arterial hypertension following chronic exposure to inorganic lead显示文摘 Boscolo P Poma A 1999Immunpharmacology1999,44,12:1
10Aluminum-induced oxidative stress in maize显示文摘BOSCOLO P R MENOSSI M JORGE R A 2003Phytochemistry2003,62,:1
11Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells显示文摘Greenberger S Boscolo E Adini I 2010N Engl J Med2010,362,:1
12How do rat cortical cells cultured with aluminum die:necrosis or apoptosis显示文摘ZHANG Q L BOSCOLO P NIU P Y 0,,1:1
13Boscolora, mi- oderate exercise training modulates cytokine profile and gleep in elderly people显示文摘Santos RV P' iana VA Boscolo RA 2012Cytokine2012,60,3:1
14Independent Component Analysis Based on Nonparametric Density Estimation显示文摘Riecardo Boscolo 2004IEEE Trans2004,15,1:1
15Complication rates of tension - free midurethral slings in the treatment of female Stress urinary incontinence: a systematic review and meta - analysis of randomized controlled trials comparing tension - free midurethral tapes to other surgical procedures and different devices 显示文摘NOVARA G GALFANO A BOSCOLO BERTO R A 2008Eur Urol2008,53,2:1
16Organotins (TBT and DBT) in water, sediments, and gastropods of the southern Venice lagoon (Italy)显示文摘BERTO D GIANI M BOSCOLO R 2007Marine Pollution Bulletin2007,55,:1
17VEGFR-1 mediates endothelial differentiation and formation of blood vessels in a murine model of infantile hemangioma显示文摘Boscolo E Mulliken JB Bischoff J 2011Am J Pathol2011,179,5:1
18Cortieosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells 显示文摘GREENBERGER S BOSCOLO E ADINI I 2010N Engl J Med2010,,:1
19Network component analysis:reconstruction of regulatory signals in biological systems 显示文摘Liao JC Boscolo R Yang YL 2003Proc Natl Acad Sci USA2003,100,15:1
20The N:Si:P molar ratio in the Strait of Gibraltar显示文摘Dafner E V Boscolo R Bryden H L 2003Geophys Res Lett2003,30,:1
返回顶部 每页显示:
共14页 首页 上一页 第1页 下一页 末页 /14 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费